Results 31 to 40 of about 249,873 (317)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Strategic Planning

Nursing Management (Springhouse), 1993
Strategic planning identifies a department's environmental factors while establishing its purpose, mission, philosophy and goals and developing a long-range plan and objectives. This hospital's practical approach mirrors the nursing process related to assessment, diagnosis and planning, implementation and evaluation.
openaire   +5 more sources

GWAS shows links between EDARADD and LRFN5 and performance in professional athletes

BMC Sports Science, Medicine and Rehabilitation
Background Research into genetic markers associated with sports performance and aerobic capacity has been gaining momentum. However, despite the discovery of numerous molecular and genetic markers, there is still a gap in understanding the variations in ...
M. V. Terekhov, R. V. Deev, A. I. Kadykova, I. H. Dzhumaniiazova, A. A. Mamchur, E. A. Zelenova, L. R. Matkava, M. V. Ivanov, D. A. Kashtanova, S. I. Mitrofanov, L. A. Golubnikova, A. I. Nekrasova, I. G. Kalashnikova, A. A. Ivashechkin, V. V. Maksyutina, O. V. Varlamova, V. S. Yudin, A. A. Keskinov, A. V. Zholinsky, S. A. Kraevoy, S. M. Yudin, V. I. Skvortsova   +21 more
doaj   +1 more source

Remodeling of the chromatin landscape in peripheral blood cells in patients with severe Delta COVID-19

Frontiers in Immunology
COVID-19 is characterized by systemic pro-inflammatory shifts with the development of serious alterations in the functioning of the immune system. Investigations of the gene expression changes accompanying the infection state provide insight into the ...
Vasiliy E. Akimov, Dmitriy I. Tychinin, Olga A. Antonova, Abusaid M. Shaymardanov, Maria D. Voronina, Kseniia A. Deinichenko, Oleg D. Fateev, Vladimir S. Yudin, Sergey M. Yudin, Vladimir E. Mukhin, Svetlana V. Romanova, Aleksandra I. Nekrasova, Anastasia S. Zhdanova, Anastasia V. Tsypkina, Ivan S. Vladimirov, Antonida V. Makhotenko, Anton A. Keskinov, Sergey A. Kraevoy, Ekaterina A. Snigir, Dmitry V. Svetlichnyy, Veronika I. Skvortsova   +20 more
doaj   +1 more source

Current Trends in Diagnostics of Viral Infections of Unknown Etiology

Viruses, 2020
Viruses are evolving at an alarming rate, spreading and inconspicuously adapting to cutting-edge therapies. Therefore, the search for rapid, informative and reliable diagnostic methods is becoming urgent as ever.
Daniel Kiselev, Alina Matsvay, Ivan Abramov, Vladimir Dedkov, German Shipulin, Kamil Khafizov   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Developing and feasibility testing of Hamdard Force: an intervention to build the capacity of a community mental health workforce in Pakistan

BMC Public Health
Background As part of a Mental Health and Psychosocial Support (MHPSS) initiative, this study presents the process of developing an intervention to build the capacity of a community mental health workforce in Pakistan - Hamdard Force (HF).
Asma Humayun, Arooj Najmussaqib, Noor ul Ain Muneeb   +2 more
doaj   +1 more source

Diagnostics of lung cancer by fragmentated blood circulating cell-free DNA based on machine learning methods

Frontiers in Medicine
IntroductionMinimally invasive diagnostics based on liquid biopsy makes it possible early detection of lung cancer (LC). The blood plasma circulating cell-free DNA (cfDNA) fragments reflect the genome and chromatin status and are considered as integral ...
Ivan O. Meshkov, Alexander P. Koturgin, Pavel V. Ershov, Liubov A. Safonova, Julia A. Remizova, Valentina V. Maksyutina, Ekaterina D. Maralova, Vasilisa A. Astafieva, Alexey A. Ivashechkin, Boris D. Ignatiev, Antonida V. Makhotenko, Ekaterina A. Snigir, Valentin V. Makarov, Vladimir S. Yudin, Anton A. Keskinov, Sergey M. Yudin, Anna S. Makarova, Veronika I. Skvortsova   +17 more
doaj   +1 more source

Determination of defence capability requirements [PDF]

Војно дело, 2016
A capability-based planning approach provides defence system with adequate response in facing uncertainty, economic constraints and risks. Determination of required defence capabilities is the most important and complex phase in capability-based planning
Stojković Dejan S., Kankaraš Milan S., Mitić Vlada M.   +2 more
doaj   +1 more source

Climate Change Adaption between Governance and Government—Collaborative Arrangements in the City of Munich

Land, 2022
Growing cities face severe land use conflicts. Urban expansion and the densification of existing built areas are increasing the pressure on green spaces, which are key for climate change adaptation.
Simone Linke, Sabrina Erlwein, Martina van Lierop, Elizaveta Fakirova, Stephan Pauleit, Werner Lang   +5 more
doaj   +1 more source