Results 41 to 50 of about 135,944 (267)

AGE-ASSOCIATED VARIABILITY OF CIRCULATING FREE DNA CHARACTERISTICS: GENOME-WIDE ANALYSIS

Journal of Bioinformatics and Genomics
The fragments of circulating free DNA (cfDNA) found in plasma are formed due to the genomic DNA degradation during cellular death. The present study is the first research of age-associated variability of cfDNA characteristics performed on the group of ...
Meshkov I.O., Remizova J.A., Makarova A.S., Primova A.A., Petrova V.A., Bukhanova A.A., Kumar N.A., Ivashechkin A.A., Makhotenko A.V., Snigir E.A., Makarov V.V., Yudin V.S., Keskinov A.A., Yudin S.M.   +13 more
doaj   +1 more source

Model of scenario development in defense planning: Integration of scenario and decision: Making methods [PDF]

Војно дело, 2017
It is almost impossible to predict the future environment today, so instead of using prediction different methods of scenario development are used. Scenario as a hypothetical situation for future environment enables exploration of different possibilities
Mitić Vlada M., Dimić Srđan H., Kankaraš Milan S.   +2 more
doaj   +1 more source

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim, Minji Kim, Nani Jung, Sung Eun Kim, Ji Yoon Kim, Mi Ae Chu, Jung Eun Kwon, Yeo Hyang Kim, So Mi Lee, Ki‐Su Park, Jeong Eun Lee, Ye Jee Shim   +11 more
wiley   +1 more source

Developing and feasibility testing of Hamdard Force: an intervention to build the capacity of a community mental health workforce in Pakistan

BMC Public Health
Background As part of a Mental Health and Psychosocial Support (MHPSS) initiative, this study presents the process of developing an intervention to build the capacity of a community mental health workforce in Pakistan - Hamdard Force (HF).
Asma Humayun, Arooj Najmussaqib, Noor ul Ain Muneeb   +2 more
doaj   +1 more source

Diagnostics of lung cancer by fragmentated blood circulating cell-free DNA based on machine learning methods

Frontiers in Medicine
IntroductionMinimally invasive diagnostics based on liquid biopsy makes it possible early detection of lung cancer (LC). The blood plasma circulating cell-free DNA (cfDNA) fragments reflect the genome and chromatin status and are considered as integral ...
Ivan O. Meshkov, Alexander P. Koturgin, Pavel V. Ershov, Liubov A. Safonova, Julia A. Remizova, Valentina V. Maksyutina, Ekaterina D. Maralova, Vasilisa A. Astafieva, Alexey A. Ivashechkin, Boris D. Ignatiev, Antonida V. Makhotenko, Ekaterina A. Snigir, Valentin V. Makarov, Vladimir S. Yudin, Anton A. Keskinov, Sergey M. Yudin, Anna S. Makarova, Veronika I. Skvortsova   +17 more
doaj   +1 more source

Current concepts of the role of viruses as an etiological factor in sepsis [PDF]

Клиническая микробиология и антимикробная химиотерапия
Sepsis is a life-threatening condition resulting from a dysregulated immune response to infection and characterized by multiple organ dysfunction. Historically, the contribution of viruses to sepsis pathogenesis has been underestimated, largely due to ...
Grigoryan D.A., Gorbacheva A.A., Matsvay A.D.   +2 more
doaj   +1 more source

Strategic Takt Planning [PDF]

Annual Conference of the International Group for Lean Construction
Reports on the use of takt tend to focus on applications aimed at so-called operational takt planning. Instead, this paper focuses on strategic takt planning. Strategic- and operational takt planning must go hand in hand. Specifically, strategic takt planning is required upfront in project delivery as it informs prospective contractors what is expected
Tommelein, ID, Emdanat, S
openaire   +1 more source

Therapeutic Apheresis in Nigeria: Awareness, Knowledge Gaps, and Readiness for Service Expansion Among Healthcare Professionals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is a specialized extracorporeal blood purification modality used in the management of complex hematologic, neurologic, and autoimmune diseases. Despite established global guidelines, its utilization in Nigeria remains largely undocumented.
Chimezie G. Okwuonu, Evelyn Idam, Benjamin Anyanwu, Zinnah Aloziem, Mkpoikanabasi Obot‐Obot, Blossom Amamchukwu, Patience Elimian, Henry Mbakwe, Chiamaka Anyanwu, Praises Maduagwuna, Olatunji Akinrodoye, Rasheed A. Balogun   +11 more
wiley   +1 more source

Hormonal and metabolic status of centenarians diagnosed with sarcopenia: Prospective, Observational Study

Российский журнал гериатрической медицины
RELEVANCE: Sarcopenia is one of the leading geriatric syndromes that increases the risk of disability, falls and injuries. This syndrome is of particular importance for centenarians aged 90 years and older, for whom a detailed analysis of the course of ...
L. V. Matchekhina, O. N. Tkacheva, E. M. Shelley, A. A. Mamchur, V. V. Erema, M. V. Bruttan, M. V. Ivanov, D. A. Kashtanova, A. M. Rumyantseva, V. S. Yudin, V. V. Makarov, A. A. Keskinov, S. A. Kraevoy, S. M. Yudin, I. D. Strazhesko   +14 more
doaj   +1 more source

Current Trends in Diagnostics of Viral Infections of Unknown Etiology

Viruses, 2020
Viruses are evolving at an alarming rate, spreading and inconspicuously adapting to cutting-edge therapies. Therefore, the search for rapid, informative and reliable diagnostic methods is becoming urgent as ever.
Daniel Kiselev, Alina Matsvay, Ivan Abramov, Vladimir Dedkov, German Shipulin, Kamil Khafizov   +5 more
doaj   +1 more source