Results 101 to 110 of about 66,927 (286)

Active regulation of the epidermal calcium profile [PDF]

, 2012
A distinct calcium profile is strongly implicated in regulating the multi-layered structure of the epidermis. However, the mechanisms that govern the regulation of this calcium profile are currently unclear.
Adams, Matthew, Mallet, Dann, Pettet, Graeme   +2 more
core   +2 more sources

Rumen Mycobiome Thiamine Metabolism Contributes to Subacute Rumen Acidosis Tolerance in Goats Through Enhancing Epithelial Cell Proliferation via IGFBP2/IGF1 Axis Activation

Exploration, EarlyView.
Schematic illustration of the mechanism underlying the differences between SARA‐susceptible and SARA‐tolerant dairy goats fed a high‐concentrate diet. SARA‐susceptible goats (HCS) exhibit low rumen pH and metabolic decline, characterized by epithelial inflammation.
Jingyi Xu, Xiaodong Chen, Yi Ma, Jianrong Ren, Guanghao Xu, Peilin Zhang, Wenhao Jia, Quanqiu Deng, Yuquan Xiao, Junhu Yao, Shengru Wu   +10 more
wiley   +1 more source

Mechanism investigation of ethosomes transdermal permeation

International Journal of Pharmaceutics: X, 2019
Ethosomes are widely used to promote transdermal permeation of both lipophilic and hydrophilic drugs, but the mechanism of interaction between the ethosomes and the skin remains unclear.
Xiao-Qian Niu, Dan-Ping Zhang, Qiong Bian, Xing-Fu Feng, Hao Li, Yue-Feng Rao, Yong-Mei Shen, Fu-Neng Geng, An-Ran Yuan, Xiao-Ying Ying, Jian-Qing Gao   +10 more
doaj   +1 more source

Occupational Exposure to Factory‐Derived Particulate Matter 2.5 Induces Cutaneous Toxicity in Workers and HaCaT Keratinocytes Through Oxidative Stress and Inflammation

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study aimed to evaluate the toxicological effects of occupational exposure to factory‐derived particulate matter (PM2.5) on human skin, emphasizing its role as a potential target organ of environmental toxicants. An epidemiological survey comparing factory and nonfactory workers was conducted by assessing their skin elasticity and color ...
Miku Tanaka, Masayuki Takaishi, Iroha Okuda, Toshiki Fujimoto, Mayumi Tsuji, Yuri Okano, Yasuhiro Ishihara, Maori Kono   +7 more
wiley   +1 more source

Ceramides metabolism and impaired epidermal barrier in cutaneous diseases and skin aging: focus on the role of the enzyme PNPLA1 in the synthesis of ω-O-acylceramides and its pathophysiological involvement in some forms of congenital ichthyoses☆

Oilseeds and fats, crops and lipids, 2019
The outermost layer of the skin, the stratum corneum, is essential for the protective barrier functions of the skin. It results from the stacking of corneocytes, the dead flattened cells resulting from epidermal terminal differentiation of underlying ...
Jonca Nathalie
doaj   +1 more source

Intradermal infections by chigger mites (Hannemania spp.) in the Andean frog Telmatobius atacamensis (Anura, Telmatobiidae) [PDF]

, 2015
Here, we report the infection of adults of the Andean frog Telmatobius atacamensis (Anura, Telmatobiidae) by leeuwenhoekiid mites of the genus Hannemania and describe the histological characteristics of the normal and infected skin and the mite's larval ...
Goldberg, Francisco Javier, Quinzio, Silvia Inés   +1 more
core  

6-Hydroxy-4-sphingenine in human epidermal ceramides.

Journal of Lipid Research, 1994
The solvent-extractable lipids of human epidermal stratum corneum consist predominantly of ceramides. In addition two non-extractable ceramides are chemically bound to the stratum corneum protein. One of the bound ceramides, constituting 50% of the bound
K J Robson, M E Stewart, S Michelsen, N D Lazo, D T Downing   +4 more
doaj   +1 more source

The Fibrous Proteins Of Stratum Corneum

Journal of Investigative Dermatology, 1976
The proteins of cow snout stratum corneum can be extracted in part with Tris buffer, pH 9.0, containing 6 M urea. Sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis shows that about half the extracted material migrates as prekeratin when the extract is treated with both SDS and mercaptoethanol; only trace amounts of the proteins migrating ...
Baden, H.P., Lee, L.D., Kubilus, J.
openaire   +2 more sources

Early Acitretin Therapy in a Patient With Harlequin Ichthyosis

JEADV Clinical Practice, EarlyView.
ABSTRACT Harlequin ichthyosis (HI) is a rare, severe congenital disorder of keratinization caused by pathogenic variants in the ABCA12 gene resulting in thick, hyperkeratotic plates, deep fissures, and characteristic facial and limb abnormalities.
Orasa Sukmark, Parith Wongkittichote, Sanchawan Wittayakornrerk   +2 more
wiley   +1 more source

Fractional CO2 Laser Combined With Topical Corticosteroids for Vulvar Lichen Simplex Chronicus: An Observational Study From an 8‐Year Single‐Center Experience

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Vulvar lichen simplex chronicus (VLSC) is a chronic inflammatory dermatosis that remains difficult to manage long term. Fractional CO2 laser (FxCO2) combined with topical corticosteroids (TCs) has emerged as a potential therapeutic strategy; however, high‐quality long‐term evidence remains limited.
Dongmei Wei, Jian Meng, Yanjun Zhu, Qiao Li, Yajing Wang, Yueyue Chen, Xiaoyu Niu   +6 more
wiley   +1 more source