Results 21 to 30 of about 39,303 (298)

Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]

, 2017
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila, Eskandani, Morteza, Farhoudi, Mehdi, Mohammadian, Reza, Rafi, Mohammad, Zamanlu, Masumeh   +5 more
core   +2 more sources

Assessing the effectiveness of primary angioplasty compared with thrombolysis and its relationship to time delay: a Bayesian evidence synthesis [PDF]

, 2007
Background: Meta-analyses of trials have shown greater benefits from angioplasty than thrombolysis after an acute myocardial infarction, but the time delay in initiating angioplasty needs to be considered.
Abrams, Keith R., Asseburg, Christian, de Belder, Mark, Fenwick, Elisabeth, Palmer, Stephen, Sculpher, Mark, Vergel, Yolanda Bravo   +6 more
core   +4 more sources

Is primary angioplasty cost effective in the UK? Results of a comprehensive decision analysis [PDF]

, 2007
Objective: To assess the cost effectiveness of primary angioplasty, compared with medical management with thrombolytic drugs, to achieve reperfusion after acute myocardial infarction ( AMI) from the perspective of the UK NHS.
Abrams, Keith, Asseburg, Christian, de Belder, Mark, Fenwick, Elisabeth, Palmer, Stephen, Sculpher, Mark, Vergel, Yolanda Bravo   +6 more
core   +2 more sources

Cost effectiveness of thrombolytic therapy with tissue plasminogen activator as compared with streptokinase for acute myocardial infarction. [PDF]

New England Journal of Medicine, 1995
BACKGROUND. Patients with acute myocardial infarction who were treated with accelerated tissue plasminogen activator (t-PA) (given over a period of 1 1/2 hours rather than the conventional 3 hours, and with two thirds of the dose given in the first 30 ...
Ark, H. A., Latky, Obert, C. M., Aliff, D. C., Avid, Aylor, Erry, L. L., Ee, Aul, A. W., Rmstrong, Abriel, Arbash, arvey, Hite, Aarten, S. L., Imoons, harlotte, N. L., Elson, Ancy, Lapp, C, Hanning, D. J., Night, Rank, H. E., Arrell, Ohn, Imes, Ric, T. J., Opol   +38 more
semanticscholar   +3 more sources

The Comparison between the Outcomes of Streptokinase and Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction

The International Journal of Frontier Sciences, 2017
Background: To compare between the outcomes of streptokinase and primary PCI in acute myocardial infarction. The inappropriate treatment, misdiagnosis, contraindications of procedures can result in complications of procedures and increased mortality of ...
Zarnab Tariq, Majid Kaleem
doaj   +1 more source

Evaluation of clinical efficacy of streptokinase by comparison with the thrombolytic agent on animal model [PDF]

Brazilian Journal of Biology
Cardiovascular disorders, including acute myocardial infarction (AMI), often lead to blood clot formation, impacting blood circulation. Streptokinase, a cost-effective and widely available thrombolytic agent, is crucial in treating thrombosis. This study
S. Yousaf, M. Arshad, F. A. Harraz, R. Masood, M. A. Zia, M. Jalalah, M. Faisal   +6 more
doaj   +1 more source

Cloning and expression of truncated and intact streptokinase molecules in E.coli and evaluation of their biological activities [PDF]

مجله بیوتکنولوژی کشاورزی, 2010
Streptokinase is the most utilized drug for thrombolytic therapy. However, due to its nonhuman origin and nonspecific activity in the absence of fibrin, its application may encounter side effects such as allergic reactions and hemorrhage respectively. It
Reza Arabi, farzin Roohvand, Daryoosh Noroozian, MohMMdreza AghSADEGHI, Arash Memarnajadian, Hossin khan ahmad, Mehdi Sadat, Fatemah Motavalli   +7 more
doaj   +1 more source

Mechanical Stability and Fibrinolytic Resistance of Clots Containing Fibrin, DNA, and Histones [PDF]

, 2013
Neutrophil extracellular traps are networks of DNA and associated proteins produced by nucleosome release from activated neutrophils in response to infection stimuli and have recently been identified as key mediators between innate immunity, inflammation,
Ammollo, Aziz, Borissoff, Brill, Brinkmann, Clark, Esmon, Esmon, Fuchs, Fuchs, Gladysheva, Gleber, Guthold, Komissarov, Komorowicz, Longstaff, Longstaff, Massberg, Nikolova, Rocha, Ruf, Ryan, Rábai, Rácz, Saha, Sands, Scrutton, Semeraro, Silva, Smeeth, Walker, Weisel, Weisel, Wohner, Xu, Yang, Yeromonahos   +36 more
core   +1 more source

Bivalirudin started during emergency transport for primary PCI. [PDF]

, 2013
BACKGROUND: Bivalirudin, as compared with heparin and glycoprotein IIb/IIIa inhibitors, has been shown to reduce rates of bleeding and death in patients undergoing primary percutaneous coronary intervention (PCI).
Berg, J. van den, Bernstein, D., Clayton, T., Clemmensen, P., Coste, P., Deliargyris, E.N., Eggink, G.J., et al., Goldstein, P., Grunsven, P. van, Hamm, C.W., Hamon, M., Hof, A. van't, Huber, K., Lapostolle, F., Nef, H., Nibbe, L., Orto, M. Campo dell', Pocock, S., Prats, J., Schuette, D., Soulat, L., Steg, P.G., Steinmetz, J., Verheugt, F.W.A., Zeymer, U.   +25 more
core   +1 more source

Multifunctional Modification of Biologically Active Substances

Vestnik Volgogradskogo Gosudarstvennogo Universiteta. Seriâ 11. Estestvennye Nauki, 2014
The article studies the interracting of oxidized cyclic cyclodextrin dextrans (CD) with the protein - bacterial streptokinase. The oxidation was carried out with potassium periodate; free aldehyde groups were formed in CD molecule during this process ...
Moskvicheva Yana Borisovna, Petrovskiy Stanislav Viktorovich, Ginak Anatoliy Iosifovich   +2 more
doaj   +1 more source