Results 141 to 150 of about 238,609 (328)

The pleiotropic transcriptional regulator NlpR contributes to the modulation of nitrogen metabolism, lipogenesis and triacylglycerol accumulation in oleaginous rhodococci [PDF]

, 2017
The regulatory mechanisms involved in lipogenesis and triacylglycerol (TAG) accumulation are largely unknown in oleaginous rhodococci. In this study a regulatory protein (here called NlpR: Nitrogen lipid Regulator), which contributes to the modulation of
Alvarez, Hector Manuel, Gago, Gabriela Marisa, Gramajo, Hugo Cesar, Hernández, Martín Alejandro, Lara, María Julia   +4 more
core   +1 more source

CRISPR-Cas9 strategy for activation of silent Streptomyces biosynthetic gene clusters

Nature Chemical Biology, 2017
Here we report an efficient CRISPR-Cas9 knock-in strategy to activate silent biosynthetic gene clusters (BGCs) in streptomycetes. We applied this one-step strategy to activate multiple BGCs of different classes in five Streptomyces species and triggered ...
Mingzi M. Zhang, F. T. Wong, Yajie Wang, S. Luo, Y. H. Lim, Elena Heng, W. Yeo, R. Cobb, Behnam Enghiad, E. Ang, Huimin Zhao   +10 more
semanticscholar   +1 more source

Diagnosis and Management of Isolated Laryngeal Sarcoidosis: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective This study reviews the existing literature on patients diagnosed with sarcoidosis isolated to the larynx to improve our understanding of the diagnosis and management of this rare condition. Data Sources Embase, PubMed, Web of Science.
Raj Malhotra, Joseph Celidonio, Nicholas Hamilton, Alexandra Filipkowski, Kenneth Yan, Rachel Kaye   +5 more
wiley   +1 more source

Characterization of six bioactive compounds from two soil-derived Streptomyces strains, F9 and F4 from Iran

Research in Pharmaceutical Sciences
Background and purpose: Actinobacteria are highly valuable in the pharmaceutical industry due to their unlimited capacity to produce natural products. In line with the screening of actinomycetes to discover new antibacterial agents, this study isolated ...
Sara Ghashghaei, Helge B. Bode, Zahra Etemadifar, Yan-Ni Shi, Peter Grün, Mohammad Reza Mofid   +5 more
doaj   +1 more source

Taxonomic Characterization and Antagonistic Efficacy of Streptomyces cavourensis SKCMM1 Isolated from Sediment of Pichavaram Mangrove Forest

Journal of Pure and Applied Microbiology, 2018
Genus Streptomyces under phylum actinobacteria has been recognized as a prolific source for production of bioactive secondary metabolites. Actinobacterial strain designated as SKCMM1 isolated from Pichavaram Mangrove forest sediment was identified as ...
Manikandan Madheslu, Ashok Kumar Marimuthu, Vaishnavi Jagannathan, Duraimurugan Kasiviswanathan, Baby Shakila Parimelazhagan, Narendhran Sadasivam   +5 more
doaj   +1 more source

Resuscitation-promoting factors possess a lysozyme-like domain [PDF]

, 2004
The novel bacterial cytokine family – resuscitation-promoting factors (Rpfs) – share a conserved domain of uncharacterized function. Predicting the structure of this domain suggests that Rpfs possess a lysozyme-like domain.
Cohen Gonsaud, M., Davies, A.P., Henderson, B., Keep, Nicholas H., Labesse, G., Ward, J.M.   +5 more
core   +1 more source

Computational Study on Potentially Active Antibacterial Compounds in Secondary Metabolites of Extremophilic Microorganisms

ChemistryOpen, EarlyView.
This study employed density functional theory (DFT) and conceptual DFT (CDFT) to calculate the structures and properties of potential antibacterial compounds derived from 16‐membered lactone ring‐containing secondary metabolites of extremophiles, as well as midecamycin.
Dilong Li, Yanni Wang, Yinhuan Huang, Hui Zhou, Xiaoyun Xia, Wei Huang, Chaojie Wang   +6 more
wiley   +1 more source

Comprehensive protection of tomato photosystem under cold stress by Streptomyces sp. TOR3209

Horticultural Science
The plant growth-promoting rhizobacterium Streptomyces sp. TOR3209 induces plant tolerance in a wide range of stress conditions. However, the protection of photosystem under cold stress has not been fully understood.
Jia Ma, Jieli Peng, Nan Jia, Xu Wang, Yuxi He, Entao Wang, Dong Hu, Zhanwu Wang   +7 more
doaj   +1 more source

Nonomuraea monospora sp. nov., an actinomycete isolated from cave soil in Thailand, and emended description of the genus Nonomuraea [PDF]

, 2012
A novel actinomycete, designated strain PT708T, was isolated from cave soil collected in Pha Tup Cave Forest Park, Nan province, Thailand. It produced compounds with antimicrobial and anticancer activities.
Lumyong, S., Nakaew, N., Sungthong, R., Yokota, A.   +3 more
core   +1 more source

Taxonomy and Broad-Spectrum Antifungal Activity of Streptomyces sp. SCA3-4 Isolated From Rhizosphere Soil of Opuntia stricta

Frontiers in Microbiology, 2019
Actinobacteria are important producers of bioactive compounds. Extreme ecosystems cause evolution of novel secondary metabolic pathways of Actinobacteria and increase the possible discovery of new biological functions of bioactive compounds.
Dengfeng Qi, L. Zou, Dengbo Zhou, Yufeng Chen, Zhufen Gao, R. Feng, Miaoyi Zhang, Kangchu Li, Jianghui Xie, Wei Wang   +9 more
semanticscholar   +1 more source