Results 51 to 60 of about 241,530 (273)

Light‐Responsive Enzyme‐Loaded Nanoparticles for Tunable Adhesion and Mechanical Wound Contraction

Advanced Functional Materials, EarlyView.
This study presents a photoactivatable enzyme‐loaded mesoporous nanoparticle system (MPDA_PaTy) that enables light‐triggered tunable tissue adhesion and facilitates mechanical wound contraction. Controlled enzymatic crosslinking at tissue or hydrogel interfaces allows on‐demand adhesion.
Junghyeon Ko, Hyeon‐Jin Kim, Jeong‐Uk Kim, Seh Ri Oh, Tae Hoon Kang, Junghwan Byun, Uk‐Jae Lee, Minglin Ma, Su‐Hwan Kim, Byung‐Gee Kim, Nathaniel S. Hwang   +10 more
wiley   +1 more source

PCA‐Based Database Mining Enables the Discovery of Bacterial Carbene Transferases for Stereodivergent Cyclopropanation

Angewandte Chemie, EarlyView.
Database mining using principal component analysis (PCA)‐based clustering enabled discovery of bacterial enzymes capable of catalyzing stereodivergent cyclopropanation of styrene. Statistical analyses of sequence data further revealed characteristic structural properties of these enzymes, highlighting the potential of the bioinformatics tools for ...
Shunsuke Kato, Koki Takeuchi, Kohei Umeda, Hisashi Kudo, Tomohisa Hasunuma, Takashi Hayashi   +5 more
wiley   +2 more sources

Consequences of the deletion of the major specialized metabolite biosynthetic pathways of Streptomyces coelicolor on the metabolome and lipidome of this strain

Microbial Biotechnology
Chassis strains, derived from Streptomyces coelicolor M145, deleted for one or more of its four main specialized metabolites biosynthetic pathways (CPK, CDA, RED and ACT), in various combinations, were constructed for the heterologous expression of ...
Clara Lejeune, Sonia Abreu, Florence Guérard, Ahmed Askora, Michelle David, Pierre Chaminade, Bertrand Gakière, Marie‐Joelle Virolle   +7 more
doaj   +1 more source

A Preliminary Assessment of Yellow Pigment from Streptomyces parvulus C5-5Y

Journal of Pure and Applied Microbiology, 2017
A yellow pigment producing potent strain Streptomyces parvulus C5-5Y (KJ624998) isolated from leather industry was used in this study. The pigmented metabolite exhibited good spectrum of antagonistic activity against common human clinical pathogens ...
A. Parimala Gnana Soundari, V. Manon Mani, V. Subhash Chandra Bose, J. Jabastin, V. Brindha Priyadarisini   +4 more
doaj   +1 more source

BAC cloning and heterologous expression of a giant biosynthetic gene cluster encoding antifungal neotetrafibricin in streptomyces rubrisoli

Frontiers in Bioengineering and Biotechnology, 2022
Polyene natural products including nystatin A1, amphotericin B, ECO-02301, and mediomycin belong to a large family of valuable antifungal polyketide compounds typically produced by soil actinomycetes. A previous study (Park et al., Front.
Heung-Soon Park, Ji-Hee Park, Hye-Jin Kim, Seung-Hoon Kang, Si-Sun Choi, Eung-Soo Kim   +5 more
doaj   +1 more source

Biosynthesis of thiocarboxylic acid-containing natural products. [PDF]

, 2018
Thiocarboxylic acid-containing natural products are rare and their biosynthesis and biological significance remain unknown. Thioplatensimycin (thioPTM) and thioplatencin (thioPTN), thiocarboxylic acid congeners of the antibacterial natural products ...
Deng, Youchao, Dong, Liao-Bin, Duan, Yanwen, He, Cyndi Qixin, Houk, KN, Huang, Yong, Kang, Dingding, Rudolf, Jeffrey D, Shen, Ben, Wang, Nan   +9 more
core   +1 more source

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

Advanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint, Tao Li, Kapil D. Patel, Will H. Zhang, Ben M. Carter, Graham J. Day, Adam W. Perriman   +6 more
wiley   +1 more source

Phylogenomic analysis of natural products biosynthetic gene clusters allows discovery of arseno-organic metabolites in model streptomycetes [PDF]

, 2016
We are indebted with Marnix Medema, Paul Straight and Sean Rovito, for useful discussions and critical reading of the manuscript, as well as with Alicia Chagolla and Yolanda Rodriguez of the MS Service of Unidad Irapuato, Cinvestav, and Araceli Fernandez
Barona-Gomez, Francisco, Cruz-Morales, Pablo, Feldmann, Jorg, Kopp, Johannes Florian, Martinez-Guerrero, Christian, Mojica, Nelly Selem, Ramos-Aboites, Hilda, Yáñez-Guerra, Luis Alfonso   +7 more
core   +1 more source

Microneedle‐Based Biofertilizer Delivery Improves Plant Growth Through Microbiome Engineering

Advanced Functional Materials, EarlyView.
This figure shows how microneedles are used to deliver biofertilizers to enhance plant growth through microbial migration, metabolic reprogramming, and changes in plant endogenous microbiome. Abstract This study presents a microneedle‐based system for the delivery of rhizospheric biofertilizers into plant tissues to enhance growth.
Zhicheng Le, Sevugan Mayalagu, Cheng‐Yen Chen, Raktim Bhattacharya, Abhishek Gupta, Jingyuan Li, Zhi Wei Norman Teo, Yufeng Shou, Arya Gopinath MP, Danni Zhong, Tedrick Thomas Salim Lew, Hao Yu, Naweed I. Naqvi, Sanjay Swarup, Andy Tay   +14 more
wiley   +1 more source

The Production of Streptomyces W-5B Extract for Antibiofilm against Methicillin-resistant Staphylococcus aureus

Journal of Pure and Applied Microbiology, 2022
The ability of Methicillin-resistant Staphylococcus aureus (MRSA) to form biofilms is one of the triggering factors for the emergence of MRSA resistance to antibiotics.
Ari Asnani, Azizah Purwanti, Windy Amalia Bakrudin, Dwi Utami Anjarwati   +3 more
doaj   +1 more source