Results 81 to 90 of about 241,530 (273)

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

Advanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin, Wangqiong Chen, Danlu Yang, Qing Liu, Baolong Bai, Zirui Dai, Xirong Liu, Zirong Zhu, Jie Rang, Liqiu Xia   +9 more
wiley   +1 more source

تولید استرپتوتریسین D توسط Streptomyces sp. جدا شده از ریزوسفر گیاه دارویی Mentha longifolia [PDF]

زیست‌شناسی کاربردی
مقدمه: اکثر آنتی‎بیوتیک‎هایی که امروزه استفاده می‎شوند توسط اکتینومیست‎ها و به ویژه جنسStreptomyces سنتز می‎شوند و به دلیل پتانسیل بالای آن‎ها برای تولید ترکیبات ضدمیکروبی، این گروه از باکتری‎ها همچنان یک منبع بالقوه برای شناسایی ترکیبات جدید هستند.
فاطمه علی نژاد, غلام خداکرمیان   +1 more
doaj   +1 more source

A novel taxonomic marker that discriminates between morphologically complex actinomycetes [PDF]

Open Biology, 2013
In the era when large whole genome bacterial datasets are generated routinely, rapid and accurate molecular systematics is becoming increasingly important.
Geneviève Girard, Bjørn A. Traag, Vartul Sangal, Nadine Mascini, Paul A. Hoskisson, Michael Goodfellow, Gilles P. van Wezel   +6 more
doaj   +1 more source

Natural product diversity of actinobacteria in the Atacama Desert [PDF]

, 2018
Natural Product diversityPeer reviewedPublisher ...
Ebel, Rainer, Jaspars, Marcel, Rateb, Mostafa E.   +2 more
core   +3 more sources

Nutritional requirements for the production of dithiolopyrrolone antibiotics by Saccharothrix algeriensis NRRL B-24137 [PDF]

, 2006
The amino acid and humic acid requirements of Saccharothrix algeriensis NRRL B-24137 for growth and production of the dithiolopyrrolone antibiotics were studied in a semi-synthetic medium (SSM).
Bouras, Noureddine, Lebrihi, Ahmed, Mathieu, Florence, Sabaou, Nasserdine   +3 more
core   +2 more sources

Structural Revision of the C16 Sesquiterpene Hegelenether and the Mechanism of C6‐Methylation in Terpene Biosynthesis

Angewandte Chemie International Edition, EarlyView.
The structure of the non‐canonical C16 sesquiterpene named hegelenether was revised to the structure of marxdiol, and its absolute configuration was assigned. Isotopic labeling experiments revealed the stereochemical course of the methyltransferase involved in its biosynthesis.
Heng Li, Gregor Schnakenburg, Michael Groll, Jeroen S. Dickschat   +3 more
wiley   +1 more source

Evaluation of antimicrobial activity of new Streptomyces species isolated from marine sediments of eastern Gilan province, Iran

Fiyz̤, 2020
Background: Streptomyces have the ability to produce bioactive metabolites such as antibacterial compounds. This study aimed to isolate and evaluate the production of antibacterial compounds from marine sediments by Streptomyces of eastern Gilan ...
Mirsonbol SZ , Issazadeh Kh, Zarrabi S , Mirpour M   +3 more
doaj  

Lipida of Streptomyces sioyaensis

Agricultural and Biological Chemistry, 1967
Three ninhydrin-positive lipids of Streptomyces sioyaensis were found. These lipids were called substance A, B and C, tentatively. Study on the distribution of these lipids in Actinomycetales has shown that substance A was common in all of the strains tested, and that substance B was found in the limited strains. The substance C was characteristic only
A, Kimura, J, Kawanami, H, Otsuka
openaire   +4 more sources

A mass spectrometry-guided genome mining approach for natural product peptidogenomics. [PDF]

, 2011
Peptide natural products show broad biological properties and are commonly produced by orthogonal ribosomal and nonribosomal pathways in prokaryotes and eukaryotes.
Cimermancic, Peter, Dorrestein, Pieter C, Fenical, William, Fischbach, Michael A, Kersten, Roland D, Moore, Bradley S, Nam, Sang-Jip, Xu, Yuquan, Yang, Yu-Liang   +8 more
core  

Resuscitation-promoting factors possess a lysozyme-like domain [PDF]

, 2004
The novel bacterial cytokine family – resuscitation-promoting factors (Rpfs) – share a conserved domain of uncharacterized function. Predicting the structure of this domain suggests that Rpfs possess a lysozyme-like domain.
Cohen Gonsaud, M., Davies, A.P., Henderson, B., Keep, Nicholas H., Labesse, G., Ward, J.M.   +5 more
core   +1 more source