Glycerol Utilization Gene Cluster in Streptomyces clavuligerus [PDF]
Applied and Environmental Microbiology, 2009 ABSTRACT The Streptomyces clavuligerus ATCC 27064 glycerol cluster gylR-glpF1K1D1 is induced by glycerol but is not affected by glucose. S. clavuligerus growth and clavulanic acid production are stimulated by glycerol, but this does not occur in a
Sonia, Baños +3 more
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Producción de compuestos bioactivos por Streptomyces clavuligerus: análisis transcriptómico diferencial entre Streptomyces clavuligerus ATCC 27064 y mutantes alterados en la producción de antibióticos [PDF]
, 2014 224 p.Streptomyces clavuligerus es un actinomiceto productor de una amplia variedad de metabolitos secundarios, como el ácido clavulánico, un inhibidor de β-lactamasas de gran interés industrial, el antibiótico β-lactámico cefamicina C y la holomicina ...
Álvarez Álvarez, Rubén
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Investigating streptomyces clavuligerus linear replicons for improved clavulanic acid production [PDF]
, 2023 Increasing antimicrobial resistance against ß-lactam antibiotics through bacterially produced ß-lactamases has prompted research into effective enzyme inhibitors, such as clavulanic acid.
Mohit, Elmira
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Screening of Natural β-lactamase Inhibitors (BLIPs) from Two Newly Isolated Egyptian Streptomyces strains [PDF]
Research Journal of Applied Biotechnology, 2023 β-lactam antibiotics are the most extensively used antibiotics to treat a variety of infections due to their safety, high selectivity, and efficacy.
Borhan Eltabey +3 more
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Genome dynamics of Streptomyces clavuligerus
Access Microbiology, 2019 Streptomyces clavuligerus is the producer of clavulanic acid; aβ-lactamaseinhibitor that is used in combination with the antibiotic amoxicillin. Genome sequencing has established that S. clavuligerus contains a linear chromosome and four linear plasmids: pSCL1, pSCL2, pSCL3 and pSCL4.
Lis Algora, Paul Herron
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Dithiolopyrrolone Natural Products : Isolation, Synthesis and Biosynthesis [PDF]
, 2013 Peer ...
Sheng Huang +7 more
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Antibiotics, 2022 Naringenin and its glycosylated derivative naringin are flavonoids that are synthesized by the phenylpropanoid pathway in plants. We found that naringenin is also formed by the actinobacterium Streptomyces clavuligerus, a well-known microorganism used to
Juan F. Martín, Paloma Liras
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MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models [PDF]
, 2012 Comparative metabolic modelling is emerging as a novel field, supported by the development of reliable and standardized approaches for constructing genome-scale metabolic models in high throughput.
Kierzek, A.M. +42 more
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Cell density influences antibiotic biosynthesis in Streptomyces clavuligerus [PDF]
Microbiology, 1996 Production of cephamycin C and clavulanic acid by Streptomyces clavuligerus took place during the exponential phase of growth in a defined medium. Both antibiotic biosynthetic pathways were activated shortly after spore germination, but the timing and kinetics of activation were affected by inoculum density.
L, Sánchez, A F, Braña
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Antimicrobial Agents and Chemotherapy, 1980 Penicillin-binding proteins of three Streptomyces strains, S. cacaoi, S. olivaceus, and S. clavuligerus, were examined by gel electrophoresis and fluorography. In a beta-lactamase producer, S. cacaoi, at least five membrane-bound penicillin-binding proteins were detected, but in two beta-lactam producers, S. olivaceus and S.
H, Ogawara, S, Horikawa
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