Results 131 to 140 of about 149 (149)
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Stresses in Redundant Mechanisms
Journal of Applied Mechanics, 1970The methods of classical kinematics and of structures are combined to determine the internal loads acting on the members of a statically indeterminant mechanism. The effect of manufacturing tolerances on stresses is investigated. For example, end play in a crank bearing caused the bending stress in a connecting rod to increase by a factor of 13.7 for ...
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Cell differentiation by mechanical stress
The FASEB Journal, 2001Growth factors, hormones, and other regulatory molecules are traditionally required in tissue engineering studies to direct the differentiation of progenitor cells along specific lineages. We demonstrate that mechanical stimulation in vitro, without ligament-selective exogenous growth and differentiation factors, induces the differentiation of ...
Gregory H. Altman +8 more
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Pathogenetic Mechanisms of Stresses
1992For a rational use of stress tests and an appropriate interpretation of their results, it may be useful to adopt a pathogenetic classification, taking into account the diagnostic end point of the test. Tests inducing vasospasm (ergonovine infusion and hyperventilation) explore the functional component (Fig. 1). Tests trying to unmask coronary stenosis (
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Electromigration and mechanical stress
Microelectronic Engineering, 1999Abstract The state of the art in the understanding of electromigration failure and mechanical stress is reviewed. First, the important concepts are introduced the effects of thermal stress and the presence of a refractory underlay is shown. Following a simplified way of qualitatively assessing the effect of various geometries on electromigration is ...
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Stress Mechanisms and Metabolic Complications
Hormone and Metabolic Research, 2007Stress can be defined as a state of threatened homeostasis or disharmony. An intricate repertoire of physiologic and behavioral responses is mobilized under stressful situations forming the adaptive stress response that aims to reestablish the challenged body equilibrium. The hypothalamic-pituitary-adrenal axis and the central and peripheral components
Constantine Tsigos, Ioannis Kyrou
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Fluid Mechanical Stress and the Platelet
Thrombosis and Haemostasis, 1975SummaryPlatelet thrombi in suspensions stirred in an aggregometer or subjected to shear flow in a Couette viscometer or circular tube can only form as a result of collisions between the cells. In whole blood, the presence of the red cells results in pronounced lateral displacements of the paths of the platelets through the vessel, which in turn ...
Jean Marlow +2 more
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Effects of stress on muscarinic mechanisms
Neuroscience & Biobehavioral Reviews, 1988Hyperactivity of muscarinic mechanisms may be involved in the patho-physiology of depressive disorders and stress. The literature emphasizes the impact of stress on aminergic networks and muscarinic mechanisms are generally not accorded a significant role in the neurobiology of stress.
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Metabolic Mechanisms of Stress Hyperglycemia
Journal of Parenteral and Enteral Nutrition, 2006Stress hyperglycemia has gained the attention of virtually every physician who encounters critically ill patients, with the emergence of clinical data supporting tight glycemic control and intensive insulinization for optimal outcome. In order to effectively manage stress hyperglycemia, newer theories of critical illness and the interactions of the ...
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microRNAs and Mechanical Stress
2011Mechanical stress, one of the major abiotic stresses, significantly affects plant growth, survival, and reproduction. Recent studies showed that cytoplasmic calcium, reactive oxygen species, and phytohormones play important roles in mechanosensing and subsequent anatomical and morphological changes in plants exposed to mechanical stress. A large number
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Oxidative stress as a mechanism of teratogenesis
Birth Defects Research Part C: Embryo Today: Reviews, 2006Emerging evidence shows that redox-sensitive signal transduction pathways are critical for developmental processes, including proliferation, differentiation, and apoptosis. As a consequence, teratogens that induce oxidative stress (OS) may induce teratogenesis via the misregulation of these same pathways.
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