Results 151 to 160 of about 7,660,214 (363)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The mechanical behaviour of polyethylene pipe systems [PDF]
, 1982 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The design of polyethylene (PE) pipelines for applications in the gas, water and chemical process industries has been based on data mainly obtained from ...
Barker, Michael, Barker, M.B.
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Thermally Induced Rock Stress Increment And Rock Reinforcement Response [PDF]
, 2016 The thermal heating caused by the deposition of spent nuclear fuel containers increases the in situ rock stress during disposal time. The thermal stress increase was modelled using thermo-mechanical modelling.
Hakala, Matti +5 more
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Reply: The stresses of cardiovascular mechanics [PDF]
The Journal of Thoracic and Cardiovascular Surgery, 2020 Keshava, Rajagopal +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Molecular Mechanism of Mechanical Stress-Induced Cardiac Hypertrophy
Japanese Heart Journal, 2000 Mechanical stress is a major cause of cardiac hypertrophy. Although the mechanisms by which mechanical load induces cardiomyocyte hypertrophy have long been a subject of great interest for cardiologists, the lack of a good in vitro system has hampered the understanding of the biochemical mechanisms.
openaire +3 more sources
Modelling and predicting fatigue crack growth behaviour in weld induced residual stress fields [PDF]
, 2011 In the last few decades, new design concepts and manufacture processes have been developed in order to reduce the maintenance and manufacturing costs, and structural weight of aircraft components. The integral metallic structure with welding processes
Servetti, Guido
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