Results 141 to 150 of about 7,660,214 (363)

Dielectric strength weakening of hexagonal boron nitride nanosheets under mechanical stress

Nature Communications
Hexagonal boron nitride (hBN) nanosheets have become the most promising candidates as gate dielectric and insulating substrates for two-dimensional (2D) material-based electronic and optoelectronic devices.
Bingjie Wang, Chuanli Yu, Yifan Jiang, Chong Tian, Jiamin Tian, Shuo Li, Zheng Fang, Menglan Li, Weilong Wu, Zhaohe Dai, Takashi Taniguchi, Kenji Watanabe, Qing Chen, Xianlong Wei   +13 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Mechanical Behaviour of Materials: Stress analysis and Mohr's circle [PDF]

, 2010
This set of animations explains how to use the Mohr's circle in stress analysis.
DoITPoMS, University of Cambridge, Dr K M Knowles, Department of Materials Science and Metallurgy, University of Cambridge, Andrew Bennett, University of Cambridge, Joanne Sharp, University of Cambridge   +3 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Intracellular Mechanical Stress‐Mediated Autophagy Cell Death via Nanospikes for Cancer Treatment

Advanced Science
Mechanical signals are fundamental regulators of cell fate, yet how cells respond to mechanical stress at the subcellular level remains unclear. Inspired by natural spiky structures that concentrate mechanical stress at the nanoscale, a series of tunable
Yingze Li, Zihan Guo, Jiawei Fan, Ruimei Zhou, Jiayan Li, Zhixiang Hu, Weicheng Gu, Mengge Zheng, Chang Xu, Yichao Tang, Chang Chen, Yu Cheng   +11 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Stress-dilatancy Relation for Mohr-Coulomb Soils Following a Non-Associated Flow Rule [PDF]

, 2010
Rowe\u27s stress–dilatancy relation for frictional (cohesionless) materials has been a cornerstone of soil mechanics. The original derivation of this relationship was based on incorrect energy minimisation considerations, but the relationship was proven ...
Salgado, Rodrigo, Zhang, J
core   +1 more source

Modelling and Prediction in Failure Processes by Mechanical Stresses in Corrosive Environment

The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2007
The complex interaction effect of mechanical stress- mechanical systems and aggressive environment, leads, at dramatic decreasing of their durability and reliability.
Liviu PALAGHIAN, Mioara THOMPSON, Svetlana BĂICEAN, Sorin BUCŞĂ   +3 more
doaj  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source