Results 131 to 140 of about 7,660,214 (363)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Glucocorticoid Alleviates Mechanical Stress-Induced Airway Inflammation and Remodeling in COPD via Transient Receptor Potential Canonical 1 Channel

open access: yesInternational Journal of COPD, 2023
Xiaojuan Wu,1 Baolin Jia,2 Xiaobin Luo,1 Jing Wang,3 Minchao Li3 1Department of Respiratory and Critical Care Medicine, Suining Central Hospital, Suining, Sichuan, 629000, People’ s Republic of China; 2Department of Oral and Maxillofacial Surgery ...
Wu X, Jia B, Luo X, Wang J, Li M
doaj  

In-situ residual stress reduction, martensitic decomposition and mechanical properties enhancement through high temperature powder bed pre-heating of Selective Laser Melted Ti6Al4V

open access: yes, 2017
During the Selective Laser Melting (SLM) process large temperature gradients can form, generating a mismatch in elastic deformation that can lead to high levels of residual stress within the additively manufactured metallic structure.
H. Ali, Le Ma, H. Ghadbeigi, K. Mumtaz
semanticscholar   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Mechanical properties of tree roots for soil reinforcement models [PDF]

open access: yes, 2001
Evidence from forestry has shown that part of the forest floor bearing capacity is delivered by tree roots. The beneficial effect however varies and diminishes with increasing number of vehicle passes. Roots potential for reinforcing the soil is known to
Cofie, P.
core  

Mechanical properties and stress analysis of natural fiber reinforced polymer composite spur gear [PDF]

open access: yes
This research study investigates the mechanical properties of polymer composites reinforced with natural fibers, specifically Palmyra palm leaf stalk fiber (PPLSF) and Palmyra palm primary leaf stalk fiber (PPFLSF).
Jayaraj, M.   +9 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Supramolecular assembly and mechanical properties of dermis [PDF]

open access: yes, 2007
The present work is a part of a wider research project which aims at the in vitro tissues and biohybrid generation. The process of generating biological tissues requires benchmarks in order to define the optimal set of design and performance parameters ...
Ventre, Maurizio
core  

Thermo-mechanical stress of bonded wires used in high power modules with alternating and direct current modes [PDF]

open access: yes, 2012
Today, power electronic reliability is a main subject of interest for many companies and laboratories. The main process leading to the IGBT failure is the cycling thermal stress.
Medjahed, Hassen   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy