Results 11 to 20 of about 129,858 (349)
Establishment of a stress granule reporter system for evaluating in vitro colon toxicity [PDF]
Animal Cells and SystemsExposure to toxic molecules from food or oral medications induces toxicity in colon cells that cause various human diseases; however, in vitro monitoring systems for colon cell toxicity are not well established.
Namjoon Cho +3 more
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Frontiers in Cell and Developmental Biology, 2021 Metabolic regulation is a necessary component of all stress response pathways, because all different mechanisms of stress-adaptation place high-energy demands on the cell.
Triana Amen +2 more
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Cellular Stress Induces Nucleocytoplasmic Transport Deficits Independent of Stress Granules
Biomedicines, 2022 Stress granules are non-membrane bound granules temporarily forming in the cytoplasm in response to stress. Proteins of the nucleocytoplasmic transport machinery were found in these stress granules and it was suggested that stress granules contribute to ...
Joni Vanneste +5 more
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A Hybrid-Body Containing Constituents of Both P-Bodies and Stress Granules Forms in Response to Hypoosmotic Stress in Saccharomyces cerevisiae. [PDF]
PLoS ONE, 2016 The cytoplasm of the eukaryotic cell is a highly compartmentalized space that contains a variety of ribonucleoprotein (RNP) granules in addition to its complement of membrane-bound organelles.
Khyati H Shah +3 more
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mRNPs meet stress granules [PDF]
FEBS Letters, 2017 Stress granules are cytoplasmic structures that form in response to a variety of cellular stresses. They contain mRNAs and many proteins including numerous types of RNA‐binding proteins, and have been studied in connection to major cellular events such as protein synthesis as well as disease. Despite the well‐known fact that stress granules encapsulate
Jonathan Sheinberger, Yaron Shav‐Tal
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Stress granules and neurodegeneration [PDF]
Nature Reviews Neuroscience, 2019 Recent advances suggest that the response of RNA metabolism to stress has an important role in the pathophysiology of neurodegenerative diseases, particularly amyotrophic lateral sclerosis, frontotemporal dementias and Alzheimer disease. RNA-binding proteins (RBPs) control the utilization of mRNA during stress, in part through the formation of ...
Benjamin Wolozin, Pavel Ivanov
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Differential effect of SARS-CoV-2 infection on stress granule formation in Vero and Calu-3 cells
Frontiers in Microbiology, 2022 Stress granule formation is induced by numerous environmental stressors, including sodium arsenite treatment and viral infection. Accordingly, stress granules can inhibit viral propagation and function as part of the antiviral host response to numerous ...
Dongbum Kim +11 more
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Stress Granule Assembly in Pulmonary Arterial Hypertension. [PDF]
CellsKosmas K +7 more
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Cell Cycle, 2012 Cell growth and proliferation are fundamental processes in living organisms and are dynamically controlled by environmental cues. TOR complex 1 (TORC1) is a central protein kinase involved in the regulation of cell growth in response to a wide variety of cellular states and is the target of the immunosuppressant and anticancer drug rapamycin.
Takahara, Terunao, Maeda, Tatsuya
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Lysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae. [PDF]
PLoS Genetics, 2017 Eukaryotic cells form stress granules under a variety of stresses, however the signaling pathways regulating their formation remain largely unknown. We have determined that the Saccharomyces cerevisiae lysine acetyltransferase complex NuA4 is required ...
Meaghen Rollins +7 more
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