Results 21 to 30 of about 72,065 (313)
Lysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae. [PDF]
PLoS Genetics, 2017 Eukaryotic cells form stress granules under a variety of stresses, however the signaling pathways regulating their formation remain largely unknown. We have determined that the Saccharomyces cerevisiae lysine acetyltransferase complex NuA4 is required ...
Meaghen Rollins +7 more
doaj +1 more source
Shear-induced mixing of granular materials featuring broad granule size distributions [PDF]
104, 2021, 044910, 2022 Granular flows during a shear-induced mixing process are studied using Discrete Element Methods. The aim is to understand the underlying elementary mechanisms of transition from unmixed to mixed phases for a granular material featuring a broad distribution of particles, which we investigate systematically by varying the strain rate and system size ...
arxiv +1 more source
Principles and Properties of Stress Granules [PDF]
Trends in Cell Biology, 2016 Stress granules are assemblies of untranslating messenger ribonucleoproteins (mRNPs) that form from mRNAs stalled in translation initiation. Stress granules form through interactions between mRNA-binding proteins that link together populations of mRNPs. Interactions promoting stress granule formation include conventional protein-protein interactions as
David S.W. Protter, Roy Parker
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SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation. [PDF]
PLoS Genetics, 2015 The SAM domain and HD domain containing protein 1 (SAMHD1) inhibits retroviruses, DNA viruses and long interspersed element 1 (LINE-1). Given that in dividing cells, SAMHD1 loses its antiviral function yet still potently restricts LINE-1, we propose that,
Siqi Hu +10 more
doaj +1 more source
Multiscale modelling of de novo anaerobic granulation [PDF]
, 2021 A multiscale mathematical model is presented to describe the de novo granulation and the evolution of multispecies granular biofilms within a continuous reactor. The granule is modelled as a spherical free boundary domain with radial symmetry. The equation which governs the free boundary is derived from global mass balance considerations and takes into
arxiv +1 more source
mRNPs meet stress granules [PDF]
FEBS Letters, 2017 Stress granules are cytoplasmic structures that form in response to a variety of cellular stresses. They contain mRNAs and many proteins including numerous types of RNA‐binding proteins, and have been studied in connection to major cellular events such as protein synthesis as well as disease. Despite the well‐known fact that stress granules encapsulate
Jonathan Sheinberger, Yaron Shav‐Tal
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Editorial: Biology of Stress Granules in Plants
Frontiers in Plant Science, 2022 Eukaryotic cells have developed sophisticated mechanisms to survive under ever-changing environments which include compartmentalization of translationally arrested mRNA molecules and proteins into a type of membraneless cytoplasmic foci called stress granules (SGs).
Monika Chodasiewicz +3 more
openaire +5 more sources
Expression of human G3BP1 in E. coli [PDF]
E3S Web of Conferences, 2021 G3BP1 (Ras-GTPase-activating protein SH3 domain-binding protein) is responsible for normal RNA stress granule (SG) assembly and overexpressed in many cancer cells. Deletion of G3BP1 decreases the number and size of SGs.
Yang Ziwei
doaj +1 more source
Stress‐induced mRNP granules: Form and function of processing bodies and stress granules [PDF]
WIREs RNA, 2019 In response to stress, cells must quickly reprogram gene expression to adapt and survive. This is achieved in part by altering levels of mRNAs and their translation into proteins. Recently, the formation of two stress‐induced messenger ribonucleoprotein (mRNP) assemblies named stress granules and processing bodies has been postulated to directly impact
Anna R. Guzikowski +2 more
openaire +4 more sources
Structural features of jammed-granulate metamaterials [PDF]
, 2023 Granular media near jamming exhibit fascinating properties, which can be harnessed to create jammed-granulate metamaterials: materials whose characteristics arise not only from the shape and material properties of the particles at the microscale, but also from the geometric features of the packing.
arxiv +1 more source