Localization to, and effects of Pbp1, Pbp4, Lsm12, Dhh1, and Pab1 on stress granules in Saccharomyces cerevisiae. [PDF]
PLoS ONE, 2010 The regulation of translation and mRNA degradation in eukaryotic cells involves the formation of cytoplasmic mRNP granules referred to as P-bodies and stress granules.
Kylie D Swisher, Roy Parker
doaj +1 more source
ZAP's stress granule localization is correlated with its antiviral activity and induced by virus replication. [PDF]
, 2019 Cellular antiviral programs encode molecules capable of targeting multiple steps in the virus lifecycle. Zinc-finger antiviral protein (ZAP) is a central and general regulator of antiviral activity that targets pathogen mRNA stability and translation ...
Jurado, Andrea +6 more
core +2 more sources
Stress‐induced mRNP granules: Form and function of processing bodies and stress granules [PDF]
WIREs RNA, 2019 In response to stress, cells must quickly reprogram gene expression to adapt and survive. This is achieved in part by altering levels of mRNAs and their translation into proteins. Recently, the formation of two stress‐induced messenger ribonucleoprotein (mRNP) assemblies named stress granules and processing bodies has been postulated to directly impact
Anna R. Guzikowski +2 more
openaire +4 more sources
Modulation of adult-born neurons in the inflamed hippocampus. [PDF]
, 2013 Throughout life new neurons are continuously added to the hippocampal circuitry involved with spatial learning and memory. These new cells originate from neural precursors in the subgranular zone of the dentate gyrus, migrate into the granule cell layer,
Belarbi, Karim, Rosi, Susanna
core +2 more sources
Plant stress granules and mRNA processing bodies are distinct from heat stress granules [PDF]
The Plant Journal, 2008 SummarySimilar to the situation in mammalian cells and yeast, messenger ribonucleo protein (mRNP) homeostasis in plant cells depends on rapid transitions between three functional states, i.e. translated mRNPs in polysomes, stored mRNPs and mRNPs under degradation.
Christian, Weber +2 more
openaire +2 more sources
Cell Reports, 2017 Most cellular stresses induce protein translation inhibition and stress granule formation. Here, using Drosophila S2 cells, we investigate the role of G3BP/Rasputin in this process.
Angelica Aguilera-Gomez +9 more
doaj +1 more source
Background-deflection Brillouin microscopy reveals altered biomechanics of intracellular stress granules by ALS protein FUS [PDF]
, 2018 Altered cellular biomechanics have been implicated as key photogenic triggers in age-related diseases. An aberrant liquid-to-solid phase transition, observed in in vitro reconstituted droplets of FUS protein, has been recently proposed as a possible ...
Antonacci, Giuseppe +3 more
core +3 more sources
Granule structure influences on force chain development in the slag medium
地质科技通报, 2022 The slag dumps formed by mining activities are irregular granular media. Their particle size gradations are complex and granule structures are unstable.The stress between particles is transferred through the dependently unstable force chain.
Minfeng Lu +5 more
doaj +1 more source
Expression of human G3BP1 in E. coli [PDF]
E3S Web of Conferences, 2021 G3BP1 (Ras-GTPase-activating protein SH3 domain-binding protein) is responsible for normal RNA stress granule (SG) assembly and overexpressed in many cancer cells. Deletion of G3BP1 decreases the number and size of SGs.
Yang Ziwei
doaj +1 more source
Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. [PDF]
, 2018 The normally soluble TAR DNA-binding protein 43 (TDP-43) is found aggregated both in reversible stress granules and in irreversible pathogenic amyloid. In TDP-43, the low-complexity domain (LCD) is believed to be involved in both types of aggregation. To
A Jain +93 more
core +1 more source