Results 61 to 70 of about 128,882 (297)
Detecting Stress Granules in Drosophila Neurons [PDF]
, 2022 Stress granules (SGs) are cytoplasmic ribonucleoprotein condensates that dynamically and reversibly assemble in response to stress. They are thought to contribute to the adaptive stress response by storing translationally inactive mRNAs as well as signaling molecules.
de Graeve, Fabienne +6 more
openaire +3 more sources
Ecotoxicology and Environmental SafetyUnder various cellular stress conditions, including exposure to toxic chemicals, RNA-binding proteins (RBPs), including Ras GTPase-activating protein-binding protein 1 (G3BP1), aggregate and form stress granule complexes, which serve as hallmarks of ...
Sangsoo Lee +6 more
doaj +1 more source
Stress granules: Guardians of cellular health and triggers of disease
Neural Regeneration ResearchStress granules are membraneless organelles that serve as a protective cellular response to external stressors by sequestering non-translating messenger RNAs (mRNAs) and regulating protein synthesis.
Meghal Desai +4 more
doaj +1 more source
Principles and Properties of Stress Granules [PDF]
Trends in Cell Biology, 2016 Stress granules are assemblies of untranslating messenger ribonucleoproteins (mRNPs) that form from mRNAs stalled in translation initiation. Stress granules form through interactions between mRNA-binding proteins that link together populations of mRNPs. Interactions promoting stress granule formation include conventional protein-protein interactions as
David S W, Protter, Roy, Parker
openaire +2 more sources
Actin and microtubules position stress granules
PRX Life, 2023 AbstractMembraneless organelles, composed of protein and nucleic acids, alter the biochemical and physical landscape of the cell. While specific membraneless organelles are found in stereotypical locations, little is known about the physical mechanisms that guide their positioning.
Thomas J. Böddeker +4 more
openaire +1 more source
Distinct stages in stress granule assembly and disassembly
eLife, 2016 Stress granules are non-membrane bound RNA-protein (RNP) assemblies that form when translation initiation is limited and contain a biphasic structure with stable core structures surrounded by a less concentrated shell.
Joshua R Wheeler +4 more
doaj +1 more source
Dilatancy, Jamming, and the Physics of Granulation [PDF]
, 2004 Granulation is a process whereby a dense colloidal suspension is converted into pasty granules (surrounded by air) by application of shear. Central to the stability of the granules is the capillary force arising from the interfacial tension between ...
Bibette J +19 more
core +2 more sources
Fasnall Induces Atypically Transient Stress Granules Independently of FASN Inhibition
iScience, 2020 Summary: Stress Granule formation has been linked to the resistance of some cancer cells to chemotherapeutic intervention. A number of studies have proposed that certain anti-tumor compounds promote cancer cell survival by inducing Stress Granule ...
Triana Amen, Daniel Kaganovich
doaj +1 more source
Effect of gestational diabetes on neuronal cells in rat cerebellum in early postnatal life [PDF]
, 2014 Previous study has shown the adverse effects of gestational diabetes on hippocampal neuronal density in animal model. This study was conducted to determine the effect of gestational diabetes on rat cerebellum in early postnatal life. In this experimental
Ghafari, S. +3 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source