Results 81 to 90 of about 4,657,064 (329)
Shigella flexnerimodulates stress granule composition and inhibits stress granule aggregation [PDF]
Cellular Microbiology, 2016 Invasion and multiplication of the facultative, cytosolic, enteropathogen Shigella flexneri within the colonic epithelial lining leads to an acute inflammatory response, fever and diarrhea. During the inflammatory process, infected cells are subjected to numerous stresses including heat, oxidative stress and genotoxic stress.
Vonaesch Pascale +4 more
openaire +3 more sources
Fasnall Induces Atypically Transient Stress Granules Independently of FASN Inhibition
iScience, 2020 Summary: Stress Granule formation has been linked to the resistance of some cancer cells to chemotherapeutic intervention. A number of studies have proposed that certain anti-tumor compounds promote cancer cell survival by inducing Stress Granule ...
Triana Amen, Daniel Kaganovich
doaj +1 more source
DDX6 modulates P-body and stress granule assembly, composition, and docking
Journal of Cell BiologyRipin et al. demonstrate that the DEAD-box helicase DDX6, a known P-body component, can also limit the formation and composition of stress granules, while also identifying P-body components that modulate the docking between P-bodies and stress granules.
Nina Ripin +3 more
semanticscholar +1 more source
Life Science Alliance, 2021 This study shows that ubiquitin conjugates associate with various types of stress granules and that an active ubiquitin system is required for the efficient clearance of some types of stress granules.
Nazife Tolay, A. Buchberger
semanticscholar +1 more source
Viral modulation of stress granules
Virus Research, 2012 Following viral infection, the host responds by mounting a robust anti-viral response with the aim of creating an unfavorable environment for viral replication. As a countermeasure, viruses have elaborated mechanisms to subvert the host response in order to maintain viral protein synthesis and production.
Valiente-Echeverría, Fernando +2 more
openaire +2 more sources
Plant stress granules and mRNA processing bodies are distinct from heat stress granules [PDF]
The Plant Journal, 2008 SummarySimilar to the situation in mammalian cells and yeast, messenger ribonucleo protein (mRNP) homeostasis in plant cells depends on rapid transitions between three functional states, i.e. translated mRNPs in polysomes, stored mRNPs and mRNPs under degradation.
Christian, Weber +2 more
openaire +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Translation Landscape of Stress Granules
Science AdvancesAbstract Stress granules, cytoplasmic assemblies of RNA-binding proteins and mRNAs formed during cellular stress, are implicated in translational control. However, their exact functions remain elusive. Here, we employed cryogenic correlative light and electron microscopy to visualize stress granules in their native environment and reconstructed
Yichun Wu +7 more
openaire +3 more sources
The Journal of Cell Biology, 2004 Nuclear stress granules are subnuclear compartments that form in response to heat shock and other stress stimuli. Although many components of nuclear stress granules have been identified, including HSF1 and pre-mRNA processing factors, their function remains a mystery. A paper in this issue describes the stress-induced transcriptional activation of one
Anton Sandqvist, Lea Sistonen
openaire +1 more source
Image-based screening for stress granule regulators
, 2021 The supplied macro provides the opportunity to analyse large-scale image datasets, derived from image-based screening approaches. It can be used as a base for the segmentation of individual cells, referred as regions of interest (ROIs), and the detection
Stoecklin, Georg, Eiermann, Nina
core +1 more source