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Editorial: Biology of Stress Granules in Plants
Eukaryotic cells have developed sophisticated mechanisms to survive under ever-changing environments which include compartmentalization of translationally arrested mRNA molecules and proteins into a type of membraneless cytoplasmic foci called stress granules (SGs).
Monika Chodasiewicz+3 more
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Stress‐induced mRNP granules: Form and function of processing bodies and stress granules [PDF]
In response to stress, cells must quickly reprogram gene expression to adapt and survive. This is achieved in part by altering levels of mRNAs and their translation into proteins. Recently, the formation of two stress‐induced messenger ribonucleoprotein (mRNP) assemblies named stress granules and processing bodies has been postulated to directly impact
Anna R. Guzikowski+2 more
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Activation of Gαq sequesters specific transcripts into Ago2 particles
The Gαq/phospholipase Cβ1 (PLCβ1) signaling system mediates calcium responses from hormones and neurotransmitters. While PLCβ1 functions on the plasma membrane, there is an atypical cytosolic population that binds Argonaute 2 (Ago2) and other proteins ...
Lela Jackson+3 more
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Role of the RNA-binding protein Nrd1 in stress granule formation and its implication in the stress response in fission yeast. [PDF]
We have previously identified the RNA recognition motif (RRM)-type RNA-binding protein Nrd1 as an important regulator of the posttranscriptional expression of myosin in fission yeast.
Ryosuke Satoh+10 more
doaj +1 more source
Structural features of jammed-granulate metamaterials [PDF]
Granular media near jamming exhibit fascinating properties, which can be harnessed to create jammed-granulate metamaterials: materials whose characteristics arise not only from the shape and material properties of the particles at the microscale, but also from the geometric features of the packing.
arxiv +1 more source
Shigella flexnerimodulates stress granule composition and inhibits stress granule aggregation [PDF]
Invasion and multiplication of the facultative, cytosolic, enteropathogen Shigella flexneri within the colonic epithelial lining leads to an acute inflammatory response, fever and diarrhea. During the inflammatory process, infected cells are subjected to numerous stresses including heat, oxidative stress and genotoxic stress.
Philippe J. Sansonetti+5 more
openaire +5 more sources
Detecting Stress Granules in Drosophila Neurons [PDF]
Stress granules (SGs) are cytoplasmic ribonucleoprotein condensates that dynamically and reversibly assemble in response to stress. They are thought to contribute to the adaptive stress response by storing translationally inactive mRNAs as well as signaling molecules.
de Graeve, Fabienne+6 more
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Cell growth and proliferation are fundamental processes in living organisms and are dynamically controlled by environmental cues. TOR complex 1 (TORC1) is a central protein kinase involved in the regulation of cell growth in response to a wide variety of cellular states and is the target of the immunosuppressant and anticancer drug rapamycin.
Tatsuya Maeda, Terunao Takahara
openaire +3 more sources
Stress granules are non-membrane bound RNA-protein granules essential for survival during acute cellular stress. TIA-1 is a key protein in the formation of stress granules that undergoes liquid-liquid phase separation by association with specific RNAs ...
Danella L. West+7 more
doaj +1 more source
Dilatancy, Jamming, and the Physics of Granulation [PDF]
Granulation is a process whereby a dense colloidal suspension is converted into pasty granules (surrounded by air) by application of shear. Central to the stability of the granules is the capillary force arising from the interfacial tension between solvent and air.
arxiv +1 more source