Results 41 to 50 of about 70,206 (162)

Biomolecular phase separation in stress granule assembly and virus infection

open access: yesActa Biochimica et Biophysica Sinica, 2023
Liquid-liquid phase separation (LLPS) has emerged as a crucial mechanism for cellular compartmentalization. One prominent example of this is the stress granule.
Liu Yi   +3 more
doaj   +1 more source

Plant stress granules and mRNA processing bodies are distinct from heat stress granules [PDF]

open access: yesThe Plant Journal, 2008
SummarySimilar to the situation in mammalian cells and yeast, messenger ribonucleo protein (mRNP) homeostasis in plant cells depends on rapid transitions between three functional states, i.e. translated mRNPs in polysomes, stored mRNPs and mRNPs under degradation.
Christian, Weber   +2 more
openaire   +2 more sources

Stress granules dynamics: benefits in cancer

open access: yesBMB Reports, 2022
Stress granules (SGs) are stress-induced subcellular compartments, which carry out a particular function to cope with stress. These granules protect cells from stress-related damage and cell death through dynamic sequestration of numerous ribonucleoproteins (RNPs) and signaling proteins, thereby promoting cell survival under both physiological and ...
Jeong In Lee, Sim Namkoong
openaire   +2 more sources

Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins

open access: yeseLife, 2020
RNA granules are protein/RNA condensates. How specific mRNAs are recruited to cytoplasmic RNA granules is not known. Here, we characterize the transcriptome and assembly of P granules, RNA granules in the C. elegans germ plasm.
Chih-Yung S Lee   +5 more
doaj   +1 more source

Stress Granules in the Post-transcriptional Regulation of Immune Cells

open access: yesFrontiers in Cell and Developmental Biology, 2021
Immune cell activation triggers transcriptional and translational programs eliciting cellular processes, such as differentiation or proliferation, essential for an efficient immune response.
Nicolas Curdy   +18 more
doaj   +1 more source

Regulation of Cellular Ribonucleoprotein Granules: From Assembly to Degradation via Post-translational Modification

open access: yesCells, 2022
Cells possess membraneless ribonucleoprotein (RNP) granules, including stress granules, processing bodies, Cajal bodies, or paraspeckles, that play physiological or pathological roles.
Pureum Jeon   +3 more
doaj   +1 more source

Viral modulation of stress granules

open access: yesVirus Research, 2012
Following viral infection, the host responds by mounting a robust anti-viral response with the aim of creating an unfavorable environment for viral replication. As a countermeasure, viruses have elaborated mechanisms to subvert the host response in order to maintain viral protein synthesis and production.
Valiente-Echeverría, Fernando   +2 more
openaire   +2 more sources

Stress granules, P-bodies and cancer [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2015
Cancer cells are exposed to adverse conditions in the tumor microenvironment, and utilize post-transcriptional control mechanisms to re-program gene expression in ways that enhance cell survival. Stress granules and processing bodies are RNA-containing granules that contribute to this process by modulating cellular signaling pathways, metabolic ...
Paul, Anderson   +2 more
openaire   +2 more sources

Detecting Stress Granules in Drosophila Neurons [PDF]

open access: yes, 2022
Stress granules (SGs) are cytoplasmic ribonucleoprotein condensates that dynamically and reversibly assemble in response to stress. They are thought to contribute to the adaptive stress response by storing translationally inactive mRNAs as well as signaling molecules.
de Graeve, Fabienne   +6 more
openaire   +3 more sources

Ribonucleoprotein Granules: Between Stress and Transposable Elements

open access: yesBiomolecules, 2023
Transposable elements (TEs) are DNA sequences that can transpose and replicate within the genome, leading to genetic changes that affect various aspects of host biology.
Sungjin Moon, Sim Namkoong
doaj   +1 more source

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