Results 41 to 50 of about 4,058,220 (323)
Multiple functions of stress granules in viral infection at a glance
Frontiers in Microbiology, 2023 Stress granules (SGs) are distinct RNA granules induced by various stresses, which are evolutionarily conserved across species. In general, SGs act as a conservative and essential self-protection mechanism during stress responses.
Yuelin Guan +7 more
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Biology Open, 2016 Stress granules are cytoplasmic foci that directly respond to the protein synthesis status of the cell. Various environmental insults, such as oxidative stress or extreme heat, block protein synthesis; consequently, mRNA will stall in translation, and ...
Cecilia Zampedri +6 more
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The Journal of Cell Biology, 2004 Nuclear stress granules are subnuclear compartments that form in response to heat shock and other stress stimuli. Although many components of nuclear stress granules have been identified, including HSF1 and pre-mRNA processing factors, their function remains a mystery. A paper in this issue describes the stress-induced transcriptional activation of one
Anton Sandqvist, Lea Sistonen
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Role of the RNA-binding protein Nrd1 in stress granule formation and its implication in the stress response in fission yeast. [PDF]
PLoS ONE, 2012 We have previously identified the RNA recognition motif (RRM)-type RNA-binding protein Nrd1 as an important regulator of the posttranscriptional expression of myosin in fission yeast.
Ryosuke Satoh +10 more
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Stress granules are shock absorbers that prevent excessive innate immune responses to dsRNA
bioRxiv, 2022 Proper defense against microbial infection depends on the controlled activation of the immune system. This is particularly important for the RIG-I-like receptors (RLRs), which recognize viral dsRNA and initiate antiviral innate immune responses with the ...
Max Paget +11 more
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Stress granules regulate stress-induced paraspeckle assembly [PDF]
Journal of Cell Biology, 2019 Eukaryotic cells contain a variety of RNA-protein macrocomplexes termed RNP granules. Different types of granules share multiple protein components; however, the crosstalk between spatially separated granules remains unaddressed. Paraspeckles and stress granules (SGs) are prototypical RNP granules localized exclusively in the nucleus and cytoplasm ...
Haiyan An +2 more
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Activation of Gαq sequesters specific transcripts into Ago2 particles
Scientific Reports, 2022 The Gαq/phospholipase Cβ1 (PLCβ1) signaling system mediates calcium responses from hormones and neurotransmitters. While PLCβ1 functions on the plasma membrane, there is an atypical cytosolic population that binds Argonaute 2 (Ago2) and other proteins ...
Lela Jackson +3 more
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Biochemistry and Biophysics Reports, 2021 Pesticides entering our body, either directly or indirectly, are known to increase the risk of developing neurodegenerative disorders. The pesticide-induced animal models of Parkinson's disease and Alzheimer's disease recapitulates many of the ...
Pratibha Bhadauriya +2 more
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Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?
Cell Death and Disease, 2021 Stress granules (SGs) are membraneless cell compartments formed in response to different stress stimuli, wherein translation factors, mRNAs, RNA-binding proteins (RBPs) and other proteins coalesce together.
Adriana Marcelo +4 more
semanticscholar +1 more source
, 2020 The capacity of cells to organize complex biochemical reactions in intracellular space is a fundamental organizational principle of life. Key to this organization is the compartmentalization of the cytoplasm into distinct organelles, which is frequently achieved through intracellular membranes.
Min-Seok, Song, Elda, Grabocka
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