Results 1 to 10 of about 341,990 (344)
Dopamine neurons projecting to the posterior striatum reinforce avoidance of threatening stimuli
Nature Neuroscience, 2018 Midbrain dopamine neurons are well known for their role in reward-based reinforcement learning. We found that the activity of dopamine axons in the posterior tail of the striatum (TS) scaled with the novelty and intensity of external stimuli, but did not
William Menegas +2 more
exaly +2 more sources
Dopamine neurons projecting to the posterior striatum form an anatomically distinct subclass
eLife, 2015 Combining rabies-virus tracing, optical clearing (CLARITY), and whole-brain light-sheet imaging, we mapped the monosynaptic inputs to midbrain dopamine neurons projecting to different targets (different parts of the striatum, cortex, amygdala, etc) in ...
William Menegas +7 more
doaj +2 more sources
On the role of the striatum in response inhibition. [PDF]
PLoS ONE, 2010 BACKGROUND: Stopping a manual response requires suppression of the primary motor cortex (M1) and has been linked to activation of the striatum. Here, we test three hypotheses regarding the role of the striatum in stopping: striatum activation during ...
Bram B Zandbelt, Matthijs Vink
doaj +1 more source
Archives of Microbiology, 2021 Corynebacterium striatum is part of microbiota of skin and nasal mucosa of humans and has been increasingly reported as the etiologic agent of community-acquired and nosocomial diseases. Antimicrobial multidrug-resistant (MDR) C.
Giorgio Silva-Santana +8 more
semanticscholar +1 more source
Pharmaceutics, 2021 The pharmacological modulation of autophagy is considered a promising neuroprotective strategy. While it has been postulated that lithium regulates this cellular process, the age-related effects have not been fully elucidated.
Angelica Jardim Costa +6 more
doaj +1 more source
Striatal ZBTB16 Is Associated With Cognitive Deficits in Alzheimer Disease Mice [PDF]
International Neurourology Journal, 2022 Purpose In Alzheimer disease (AD), brain regions such as the cortex and the hippocampus show abundant amyloid load which correlates with cognitive function decline.
Sangjoon Lee +4 more
doaj +1 more source
Effects of prolactin on movement disorders and APOE, GFAP, and PRL receptor gene expression following intracerebral hemorrhage in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Intracerebral hemorrhage (ICH) occurs mostly in the striatum. In ICH, blood prolactin level increases 3-fold. The effects of intracerebroventricular injection (ICV) of prolactin on motor disorders will be investigated. Materials and Methods:
Shiba Yousefvand +6 more
doaj +1 more source
Schizophrenia, Dopamine and the Striatum: From Biology to Symptoms
Trends in Neurosciences, 2019 The mesolimbic hypothesis has been a central dogma of schizophrenia for decades, positing that aberrant functioning of midbrain dopamine projections to limbic regions causes psychotic symptoms.
R. McCutcheon, A. Abi-Dargham, O. Howes
semanticscholar +1 more source
Dissociable Roles of Ventral and Dorsal Striatum in Instrumental Conditioning
Science, 2004 Instrumental conditioning studies how animals and humans choose actions appropriate to the affective structure of an environment. According to recent reinforcement learning models, two distinct components are involved: a “critic,” which learns to predict
J. O’Doherty +5 more
semanticscholar +1 more source
Implication of ermCX gene of Corynebacterium striatum in macrolide resistance in Beijing, China
Bangladesh Journal of Pharmacology, 2013 To study the resistance mechanism of Corynebacterium striatum clinical isolates to macrolide antibiotic, 57 strains of C. striatum clinical isolates were detected by susceptibility testing, PCR amplification and DNA sequencing.
Wei Li, Zheng Zhang
doaj +1 more source