Dystonia: sparse synapses for D2 receptors in striatum of a DYT1 knock-out mouse model [PDF]
Dystonia pathophysiology has been partly linked to downregulation and dysfunction of dopamine D2 receptors in striatum. We aimed to investigate the possible morpho-structural correlates of D2 receptor downregulation in the striatum of a DYT1 Tor1a mouse ...
Biagioni, S. +8 more
core +1 more source
When good bugs go bad: Epidemiology and antimicrobial resistance profiles of Corynebacterium striatum, an emerging multidrug-resistant, opportunistic pathogen [PDF]
Infections with Corynebacterium striatum have been described in the literature over the last 2 decades, with the majority being bacteremia, central line infections, and occasionally, endocarditis.
Anderson, Neil +4 more
core +2 more sources
Human Dorsal Striatal Activity during Choice Discriminates Reinforcement Learning Behavior from the Gambler’s Fallacy [PDF]
Reinforcement learning theory has generated substantial interest in neurobiology, particularly because of the resemblance between phasic dopamine and reward prediction errors.
Jessup, Ryan K., O'Doherty, John P.
core +1 more source
Overlapping neural systems represent cognitive effort and reward anticipation [PDF]
Anticipating a potential benefit and how difficult it will be to obtain it are valuable skills in a constantly changing environment. In the human brain, the anticipation of reward is encoded by the Anterior Cingulate Cortex (ACC) and Striatum. Naturally,
Achten, Eric +5 more
core +11 more sources
Contextual novelty changes reward representations in the striatum [PDF]
Reward representation in ventral striatum is boosted by perceptual novelty, although the mechanism of this effect remains elusive. Animal studies indicate a functional loop (Lisman and Grace, 2005) that includes hippocampus, ventral striatum, and ...
Bunzeck, N. +4 more
core +1 more source
The neural basis of unwanted thoughts during resting state. [PDF]
Human beings are constantly engaged in thought. Sometimes thoughts occur repetitively and can become distressing. Up to now the neural bases of these intrusive or unwanted thoughts is largely unexplored.
De Raedt, Rudi +3 more
core +2 more sources
Striatal dopamine is involved in facilitation of motor action as well as various cognitive and emotional functions. Positron emission tomography (PET) is the primary imaging method used to investigate dopamine function in humans.
Filip Grill +14 more
doaj +1 more source
The Effects of Acute Stress Exposure on Neural Correlates of Pavlovian Conditioning with Monetary Gains and Losses [PDF]
Pavlovian conditioning involves the association of an inherently neutral stimulus with an appetitive or aversive outcome, such that the neutral stimulus itself acquires reinforcing properties.
Delgado, Mauricio R. +2 more
core +3 more sources
Decreased dopamine activity predicts relapse in methamphetamine abusers. [PDF]
Studies in methamphetamine (METH) abusers showed that the decreases in brain dopamine (DA) function might recover with protracted detoxification. However, the extent to which striatal DA function in METH predicts recovery has not been evaluated.
Alia-Klein, N +11 more
core +1 more source
NT-4/5 Exacerbates Free Radical-Induced Neuronal Necrosis in Vitro and in Vivo
Neurotrophins render neurons highly vulnerable to certain injuries. We examined the possibility that NT-4/5 would enhance free radical neurotoxicity in vivo as well as in vitro.
Seok J. Won +6 more
doaj +1 more source

