Results 21 to 30 of about 325,395 (379)

Dopamine D2Rs coordinate cue-evoked changes in striatal acetylcholine levels

open access: yeseLife, 2022
In the striatum, acetylcholine (ACh) neuron activity is modulated co-incident with dopamine (DA) release in response to unpredicted rewards and reward-predicting cues and both neuromodulators are thought to regulate each other.
Kelly M Martyniuk   +5 more
doaj   +1 more source

Human Dorsal Striatal Activity during Choice Discriminates Reinforcement Learning Behavior from the Gambler’s Fallacy [PDF]

open access: yes, 2011
Reinforcement learning theory has generated substantial interest in neurobiology, particularly because of the resemblance between phasic dopamine and reward prediction errors.
Jessup, Ryan K., O'Doherty, John P.
core   +1 more source

Dissociable Roles of Ventral and Dorsal Striatum in Instrumental Conditioning

open access: yesScience, 2004
Instrumental conditioning studies how animals and humans choose actions appropriate to the affective structure of an environment. According to recent reinforcement learning models, two distinct components are involved: a “critic,” which learns to predict
J. O’Doherty   +5 more
semanticscholar   +1 more source

Implication of ermCX gene of Corynebacterium striatum in macrolide resistance in Beijing, China

open access: yesBangladesh Journal of Pharmacology, 2013
To study the resistance mechanism of Corynebacterium striatum clinical isolates to macrolide antibiotic, 57 strains of C. striatum clinical isolates were detected by susceptibility testing, PCR amplification and DNA sequencing.
Wei Li, Zheng Zhang
doaj   +1 more source

Forebrain NgR1 Overexpression Impairs DA Release Suggesting Synergy of Local and Global Synaptic Plasticity Mechanisms

open access: yesFrontiers in Synaptic Neuroscience, 2020
Structural synaptic reorganizations needed to permanently embed novel memories in the brain involve complex plasticity-enhancing and plasticity-inhibiting systems.
Emma Arvidsson   +4 more
doaj   +1 more source

Contextual novelty changes reward representations in the striatum [PDF]

open access: yes, 2010
Reward representation in ventral striatum is boosted by perceptual novelty, although the mechanism of this effect remains elusive. Animal studies indicate a functional loop (Lisman and Grace, 2005) that includes hippocampus, ventral striatum, and ...
Bunzeck, N.   +4 more
core   +1 more source

The Sensory Striatum [PDF]

open access: yesNeuron, 2014
The dorsal striatum is regarded as a substrate for action selection and motor habits, but much of it is connected to sensory, not motor, cortex. In this issue of Neuron, Reig and Silberberg (2014) use intracellular recording to reveal connections between sensory cortex and striatum.
openaire   +3 more sources

Overlapping Prediction Errors in Dorsal Striatum During Instrumental Learning With Juice and Money Reward in the Human Brain [PDF]

open access: yes, 2009
Prediction error signals have been reported in human imaging studies in target areas of dopamine neurons such as ventral and dorsal striatum during learning with many different types of reinforcers. However, a key question that has yet to be addressed is
O'Doherty, John P., Valentin, Vivian V.
core   +2 more sources

Dopamine neurons projecting to the posterior striatum reinforce avoidance of threatening stimuli

open access: yesNature Neuroscience, 2018
Midbrain dopamine neurons are well known for their role in reward-based reinforcement learning. We found that the activity of dopamine axons in the posterior tail of the striatum (TS) scaled with the novelty and intensity of external stimuli, but did not
William Menegas   +4 more
semanticscholar   +1 more source

The neural basis of unwanted thoughts during resting state. [PDF]

open access: yes, 2013
Human beings are constantly engaged in thought. Sometimes thoughts occur repetitively and can become distressing. Up to now the neural bases of these intrusive or unwanted thoughts is largely unexplored.
De Raedt, Rudi   +3 more
core   +2 more sources

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