Results 21 to 30 of about 325,395 (379)
Dopamine D2Rs coordinate cue-evoked changes in striatal acetylcholine levels
In the striatum, acetylcholine (ACh) neuron activity is modulated co-incident with dopamine (DA) release in response to unpredicted rewards and reward-predicting cues and both neuromodulators are thought to regulate each other.
Kelly M Martyniuk+5 more
doaj +1 more source
Human Dorsal Striatal Activity during Choice Discriminates Reinforcement Learning Behavior from the Gambler’s Fallacy [PDF]
Reinforcement learning theory has generated substantial interest in neurobiology, particularly because of the resemblance between phasic dopamine and reward prediction errors.
Jessup, Ryan K., O'Doherty, John P.
core +1 more source
Dissociable Roles of Ventral and Dorsal Striatum in Instrumental Conditioning
Instrumental conditioning studies how animals and humans choose actions appropriate to the affective structure of an environment. According to recent reinforcement learning models, two distinct components are involved: a “critic,” which learns to predict
J. O’Doherty+5 more
semanticscholar +1 more source
Implication of ermCX gene of Corynebacterium striatum in macrolide resistance in Beijing, China
To study the resistance mechanism of Corynebacterium striatum clinical isolates to macrolide antibiotic, 57 strains of C. striatum clinical isolates were detected by susceptibility testing, PCR amplification and DNA sequencing.
Wei Li, Zheng Zhang
doaj +1 more source
Structural synaptic reorganizations needed to permanently embed novel memories in the brain involve complex plasticity-enhancing and plasticity-inhibiting systems.
Emma Arvidsson+4 more
doaj +1 more source
Contextual novelty changes reward representations in the striatum [PDF]
Reward representation in ventral striatum is boosted by perceptual novelty, although the mechanism of this effect remains elusive. Animal studies indicate a functional loop (Lisman and Grace, 2005) that includes hippocampus, ventral striatum, and ...
Bunzeck, N.+4 more
core +1 more source
The dorsal striatum is regarded as a substrate for action selection and motor habits, but much of it is connected to sensory, not motor, cortex. In this issue of Neuron, Reig and Silberberg (2014) use intracellular recording to reveal connections between sensory cortex and striatum.
openaire +3 more sources
Overlapping Prediction Errors in Dorsal Striatum During Instrumental Learning With Juice and Money Reward in the Human Brain [PDF]
Prediction error signals have been reported in human imaging studies in target areas of dopamine neurons such as ventral and dorsal striatum during learning with many different types of reinforcers. However, a key question that has yet to be addressed is
O'Doherty, John P., Valentin, Vivian V.
core +2 more sources
Dopamine neurons projecting to the posterior striatum reinforce avoidance of threatening stimuli
Midbrain dopamine neurons are well known for their role in reward-based reinforcement learning. We found that the activity of dopamine axons in the posterior tail of the striatum (TS) scaled with the novelty and intensity of external stimuli, but did not
William Menegas+4 more
semanticscholar +1 more source
The neural basis of unwanted thoughts during resting state. [PDF]
Human beings are constantly engaged in thought. Sometimes thoughts occur repetitively and can become distressing. Up to now the neural bases of these intrusive or unwanted thoughts is largely unexplored.
De Raedt, Rudi+3 more
core +2 more sources