Results 31 to 40 of about 278,206 (253)
Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair: 40 Years in Perspective
The ability of new neurons to promote repair of brain circuitry depends on their capacity to re-establish afferent and efferent connections with the host.
Anders Björklund, Malin Parmar
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Why we interact : on the functional role of the striatum in the subjective experience of social interaction [PDF]
Acknowledgments We thank Neil Macrae and Axel Cleeremans for comments on earlier versions of this manuscript. Furthermore, we are grateful to Dorothé Krug and Barbara Elghahwagi for their assistance in data acquisition.
Bente, Gary +6 more
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The dorsal striatum is regarded as a substrate for action selection and motor habits, but much of it is connected to sensory, not motor, cortex. In this issue of Neuron, Reig and Silberberg (2014) use intracellular recording to reveal connections between sensory cortex and striatum.
openaire +2 more sources
Frontostriatal Maturation Predicts Cognitive Control Failure to Appetitive Cues in Adolescents [PDF]
Adolescent risk-taking is a public health issue that increases the odds of poor lifetime outcomes. One factor thought to influence adolescents' propensity for risk-taking is an enhanced sensitivity to appetitive cues, relative to an immature capacity to ...
B. J. Casey +7 more
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Basal ganglia role in learning rewarded actions and executing previously learned choices: Healthy and diseased states [PDF]
The basal ganglia (BG) is a collection of nuclei located deep beneath the cerebral cortex that is involved in learning and selection of rewarded actions. Here, we analyzed BG mechanisms that enable these functions.
Atwood, Brady +2 more
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The ultimate goal of the treatment of schizophrenia is recovery, a notion related to improvement of cognitive and social functioning. Cognitive remediation therapies (CRT), one of the most effective cognition enhancing methods, have been shown to ...
Kazuyoshi Takeda +7 more
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In addition to neuronal migration, brain development, and adult plasticity, the extracellular matrix protein Reelin has been extensively implicated in human psychiatric disorders such as schizophrenia, bipolar disorder, and autism spectrum disorder ...
Mònica Pardo +28 more
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Dopamine-D1 and δ-opioid receptors co-exist in rat striatal neurons [PDF]
Cocaine’s enhancement of dopaminergic neurotransmission in the mesolimbic pathway plays a critical role in the initial reinforcing properties of this drug. However, other neurotransmitter systems are also integral to the addiction process.
Ambrose-Lanci, L. M. +3 more
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Shank3 is an excitatory postsynaptic scaffolding protein implicated in multiple brain disorders, including autism spectrum disorders (ASD) and Phelan-McDermid syndrome (PMS). Although previous neurobiological studies on Shank3 and Shank3-mutant mice have
Taesun Yoo +9 more
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Dopamine-modulated dynamic cell assemblies generated by the GABAergic striatal microcircuit [PDF]
The striatum, the principal input structure of the basal ganglia, is crucial to both motor control and learning. It receives convergent input from all over the neocortex, hippocampal formation, amygdala and thalamus, and is the primary recipient of ...
Alexander +92 more
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