Results 31 to 40 of about 665,456 (302)
Digging out evidences on escherichia coli stringent response from scientific literature [PDF]
, 2009 Carneiro, S. +5 more
core +2 more sources
Tolerance and Persistence to Drugs: A Main Challenge in the Fight Against Mycobacterium tuberculosis
Frontiers in Microbiology, 2020 The treatment of tuberculosis is extremely long. One of the reasons why Mycobacterium tuberculosis elimination from the organism takes so long is that in particular environmental conditions it can become tolerant to drugs and/or develop persisters able ...
Francesca Boldrin +4 more
doaj +1 more source
Clinical rel mutations in Staphylococcus aureus prime pathogen expansion under nutrient stress
mSphere, 2023 Persistent infection by Staphylococcus aureus has been linked to the bacterial stringent response (SR), a conserved stress response pathway regulated by the Rel protein.
Edwin Chen +6 more
doaj +1 more source
Bacterial lifestyle shapes stringent response activation [PDF]
Trends in Microbiology, 2013 Bacteria inhabit enormously diverse niches and have a correspondingly large array of regulatory mechanisms to adapt to often inhospitable and variable environments. The stringent response (SR) allows bacteria to quickly reprogram transcription in response to changes in nutrient availability. Although the proteins controlling this response are conserved
Cara C, Boutte, Sean, Crosson
openaire +2 more sources
Bakterien unter Stress - die stringent response [PDF]
BIOspektrum, 2020 AbstractThe ability of microorganisms to cope with a large variety of environmental conditions is one of their most outstanding features. This review gives an overview over the metabolism and targets of ppGpp and pppGpp, the second messengers mediating resource allocation and adaptation to unfavourable conditions by triggering the ‘stringent response’.
Wieland Steinchen, Gert Bange
openaire +1 more source
Synthetic (p)ppGpp analogue is an inhibitor of stringent response in mycobacteria [PDF]
, 2017 Bacteria elicit an adaptive response against hostile conditions such as starvation and other kinds of stresses. Their ability to survive such conditions depends, in part, on stringent response pathways.
Bhardwaj, Neerupma +6 more
core +2 more sources
Microbiology Spectrum, 2023 In natural environments, nutrients are usually scarce, causing microorganisms to grow slowly while staying metabolically active. These natural conditions can be simulated using retentostat cultivations.
Angela Rocio Ortiz Camargo +6 more
doaj +1 more source
Mutation of rpoB Shifts the Nutrient Threshold Triggering Myxococcus Multicellular Development
Frontiers in Microbiology, 2022 The ability to perceive and respond to environmental change is essential to all organisms. In response to nutrient depletion, cells of the soil-dwelling δ-proteobacterium Myxococcus xanthus undergo collective morphogenesis into multicellular fruiting ...
Sabrina A. Eisner +2 more
doaj +1 more source
The stringent response and Mycobacterium tuberculosis pathogenesis [PDF]
Pathogens and Disease, 2018 AbstractDuring infection, the host restrains Mycobacterium tuberculosis (Mtb) from proliferating by imposing an arsenal of stresses. Despite this onslaught of attacks, Mtb is able to persist for the lifetime of the host, indicating that this pathogen has substantial molecular mechanisms to resist host-inflicted damage.
Jerome, Prusa +2 more
openaire +2 more sources
Orphan Toxin OrtT (YdcX) of Escherichia coli Reduces Growth during the Stringent Response
Toxins, 2015 Toxin/antitoxin (TA) systems are nearly universal in prokaryotes; toxins are paired with antitoxins which inactivate them until the toxins are utilized. Here we explore whether toxins may function alone; i.e., whether a toxin which lacks a corresponding ...
Sabina Islam +2 more
doaj +1 more source