Results 41 to 50 of about 2,448,479 (335)

A new mechanical structural damage feature index based on HHT [PDF]

, 2018
A new damage feature index is presented for the structural health monitoring based on Hilbert-Huang transform (HHT). The energy marginal spectrum of the dynamic signal is used to construct damage characteristic parameter, which can reflect the signal ...
Hua, Lin, Wang, Fusheng, Yue, Zhufeng
core   +3 more sources

Cataloging Plant Genome Structural Variations [PDF]

Current Issues in Molecular Biology, 2017
Structural variation (SV) is a type of genetic variation identified through the comparison of genome structures which often have direct and significant associations with phenotypic variations. Building on the next generation sequencing (NGS) technologies, research on plant structural variations are gaining momentum and have revolutionized our view on ...
Zhang, Xingtan, Chen, Xuequn, Liang, Pingping, Tang, Haibao   +3 more
openaire   +3 more sources

Multi-Contrast MRI Reconstruction with Structure-Guided Total Variation

, 2015
Magnetic resonance imaging (MRI) is a versatile imaging technique that allows different contrasts depending on the acquisition parameters. Many clinical imaging studies acquire MRI data for more than one of these contrasts---such as for instance T1 and ...
Betcke, Marta M., Ehrhardt, Matthias J.
core   +1 more source

Second harmonic generation polarization microscopy as a tool for protein structure analysis

Biophysics and Physicobiology, 2019
Cryo-electron microscopy and X-ray crystallography have been the major tools of protein structure analysis for decades and will certainly continue to be essential in the future.
Junichi Kaneshiro, Yasushi Okada, Tomohiro Shima, Mika Tsujii, Katsumi Imada, Taro Ichimura, Tomonobu M. Watanabe   +6 more
doaj   +1 more source

Discovery and genotyping of structural variation from long-read haploid genome sequence data [PDF]

, 2016
In an effort to more fully understand the full spectrum of human genetic variation, we generated deep single-molecule, real-time (SMRT) sequencing data from two haploid human genomes.
Boitano, Matthew, Chaisson, Mark J.P., Chin, Chen-Shin, Eichler, Evan E, Gordon, David, Graves-Lindsay, Tina A, Hoekzema, Kendra, Huddleston, John, Korlach, Jonas, Kronenberg, Zev N, Munson, Katherine M, Peluso, Paul, Steinberg, Karyn Meltz, Vives, Laura, Warren, Wes, Wilson, Richard K   +15 more
core   +2 more sources

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Optical Genome Mapping Reveals the Landscape of Structural Variations and Their Clinical Significance in HBOC-Related Breast Cancer

Frontiers in Bioscience-Landmark
Background: Structural variations (SVs) are common genetic alterations in the human genome. However, the profile and clinical relevance of SVs in patients with hereditary breast and ovarian cancer (HBOC) syndrome (germline BRCA1/2 mutations) remains to ...
Yanan Cheng, Li Dong, Dechao Bu, Lei Han, Yi Zhao, Juntian Liu, Xiaojing Guo, Hanli Xu, Jinpu Yu   +8 more
doaj   +1 more source

MATCHCLIP: Locate precise breakpoints for copy number variation using CIGAR string by matching soft clipped reads

Frontiers in Genetics, 2013
Copy number variations (CNVs) are associated with many complex diseases. Next generation sequencing data enable one to identify precise CNV breakpoints to better under the underlying molecular mechanisms and to design more efficient assays.
Yinghua eWu, Lifeng eTian, Mario ePirastu, Dwight eStambolian, Hongzhe eLi   +4 more
doaj   +1 more source

Prediction of structural variation

Current Opinion in Structural Biology
Proteins are dynamic molecules that transition between conformational states to perform their functions, and characterizing the protein ensemble is important for understanding biology and therapeutic applications. While recent breakthroughs in machine learning have enabled the prediction of high-quality static models of individual proteins, generating ...
Yogesh Kalakoti, Airy Sanjeev, Björn Wallner   +2 more
openaire   +3 more sources

Modulational Instability and Variational Structure [PDF]

Studies in Applied Mathematics, 2014
We study the modulational instability of periodic traveling waves for a class of Hamiltonian systems in one spatial dimension. We examine how the Jordan block structure of the associated linearized operator bifurcates for small values of the Floquet exponent to derive a criterion governing instability to long wavelengths perturbations in terms of the ...
Bronski, J. C., Hur, V. M.
openaire   +2 more sources