Results 61 to 70 of about 25,312 (210)

Quantitative 2D Nuclear Magnetic Resonance of Complex Mixtures: From General Analytical Homo/Heteronuclear Methods to Intrinsically Quantitative HSQC Approaches

Chemistry–Methods, Volume 6, Issue 7, July 2026.
Quantitative 2D nuclear magnetic resonance methods provide accurate individual analyte concentrations in complex mixtures. This review provides a unified description and comparison of such methods, together with an overview of applications and practical implementation tips. Quantitative 2D nuclear magnetic resonance (NMR) spectroscopy has emerged as an
Jérémy Marchand, Estelle Martineau, Jonathan Farjon, Patrick Giraudeau   +3 more
wiley   +1 more source

Enhancement of Avoidance Learning by Strychnine Sulfate

, 1965
Using a .1% solution of strychnine sulfate in normal saline, the shock avoidance lever pressing of 3 groups of Wistar rats was tested with the following pre-trial intraperitoneal injections: (1) 1 mg/kg of strychnine, (2) .5 mg/kg of strychnine and (3 ...
G. C. Theologus, R. G. Gibby, G. B. Kish
core   +1 more source

Light‐Driven [2 + 2] Cycloaddition Strategies for the Synthesis of Cyclobuta[b]indoles and Their Derivatives

ChemPhotoChem, Volume 10, Issue 6, June 2026.
This review surveys the literature on light‐driven dearomative [2+2] cycloadditions of indoles, highlighting their power to access complex cyclobuta[b]indole frameworks. Advances in photocatalysis, sensitizer design, and reaction engineering enable selective and sustainable assembly of strained three‐dimensional architectures, expanding opportunities ...
Maria Chiara Cabua, Davide Moi, Alberto Luridiana, Francesco Secci, Emanuele Cocco   +4 more
wiley   +1 more source

Functional analysis of a bitter gustatory receptor highly expressed in the larval maxillary galea of Helicoverpa armigera.

PLoS Genetics, 2022
Many plant secondary substances are feeding deterrents for insects and play a key role in the selection of host plants. The taste sensilla of phytophagous insects contain gustatory sensory neurons sensitive to deterrents but the molecular basis of ...
Yan Chen, Pei-Chao Wang, Shuai-Shuai Zhang, Jun Yang, Guo-Cheng Li, Ling-Qiao Huang, Chen-Zhu Wang   +6 more
doaj   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, Volume 3, Issue 2, Page 237-251, June 2026.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Strychnine and its mono- and dimeric analogues:a pharmaco-chemical perspective

, 2022
Covering: up to November 2021Since its isolation in 1818, strychnine has attracted the attention of a plethora of chemists and pharmacologists who have established its structure, developed total syntheses, and examined its complex pharmacology.
Jensen, Anders A, Zlotos, Darius P, Mandour, Yasmine M   +2 more
core   +1 more source

Important Poisonous Plants in Tibetan Ethnomedicine

Toxins, 2015
Tibetan ethnomedicine is famous worldwide, both for its high effectiveness and unique cultural background. Many poisonous plants have been widely used to treat disorders in the Tibetan medicinal system.
Lijuan Ma, Ronghui Gu, Li Tang, Ze-E Chen, Rong Di, Chunlin Long   +5 more
doaj   +1 more source

G Protein‐Coupled Receptor 17 (Gpr17) Enhances Leptin and Insulin Sensitivity in Lean and Obese Mouse Models

Obesity, Volume 34, Issue S1, Page 77-87, June 2026.
This study identifies G protein‐coupled receptor 17 (Gpr17) as a novel regulator of leptin and insulin sensitivity. Using complementary knockout models, we demonstrate that Gpr17 deletion enhances energy expenditure, restores leptin responsiveness, and improves insulin sensitivity, revealing Gpr17 as a potential therapeutic GPCR target for obesity and ...
Xun Sun, Connor Mahler, Natalie D. Stull, Ali Nasiri, Baohua Zhou, Varman Samuel, Gerald Shulman, Jonathan N. Flak, Hongxia Ren   +8 more
wiley   +1 more source

STRYCHNINE AND BRUCINE. PART I. THE ALKALINE DEGRADATION OF STRYCHNINE.

, 1939
Distillation of strychnine with potassium hydroxide gives among the products a base (picrate, m.p.
RAFAT HUSAIN SIDDIQUI
core   +1 more source

Blocking glycine receptors reduces neuroinflammation and restores neurotransmission in cerebellum through ADAM17-TNFR1-NF-κβ pathway

Journal of Neuroinflammation, 2020
Background Chronic hyperammonemia induces neuroinflammation in cerebellum, with glial activation and enhanced activation of the TNFR1-NF-kB-glutaminase-glutamate-GABA pathway. Hyperammonemia also increases glycinergic neurotransmission. These alterations
Yaiza M. Arenas, Andrea Cabrera-Pastor, Nora Juciute, Eloy Mora-Navarro, Vicente Felipo   +4 more
doaj   +1 more source