Results 101 to 110 of about 7,584 (205)

A longitudinal study of radiodensity and radiographic appearance of the proximal sesamoid bones in Thoroughbred racehorses

Equine Veterinary Journal, Volume 58, Issue 4, Page 946-958, July 2026.
Abstract Background There are limited data on long‐term follow‐up of radiographic changes of the proximal sesamoid bones (PSBs) in Thoroughbred racehorses. The effect of training and racing on radiodensity of the PSBs in live Thoroughbreds has not been described.
Koppány Boros, Sue Dyson, Danica Pollard, Annamária Nagy   +3 more
wiley   +1 more source

Subchondral injection of human umbilical cord mesenchymal stem cells ameliorates knee osteoarthritis by inhibiting osteoblast apoptosis and TGF-beta activity

Stem Cell Research & Therapy
Background Osteoarthritis (OA) is a common degenerative disease caused by multiple pathological mechanisms wherein subchondral bone malfunction plays a substantial role.
Congzi Wu, HuiHui Xu, Zhen Wu, Haipeng Huang, Qinwen Ge, Jianbo Xu, Jiali Chen, Pinger Wang, Wenhua Yuan, Hongting Jin, Peijian Tong   +10 more
doaj   +1 more source

Joint unloading implant modifies subchondral bone trabecular structure in medial knee osteoarthritis: 2-year outcomes of a pilot study using fractal signature analysis

, 2015
Larry E Miller,1,2 Miki Sode,3 Thomas Fuerst,3 Jon E Block2 1Miller Scientific Consulting, Inc., Asheville, NC, USA; 2The Jon Block Group, San Francisco, CA, USA; 3Bioclinica, Newark, CA, USA Background: Knee osteoarthritis (OA) is largely attributable
Miller LE, Fuerst T, Block JE, Sode M
core  

Distal interphalangeal joint capsule enthesopathy of the middle phalanx and articular cartilage loss

Equine Veterinary Journal, Volume 58, Issue 4, Page 1041-1048, July 2026.
Abstract Background Significant distal interphalangeal joint (DIPJ) pathology, particularly affecting soft tissue and articular cartilage, is often not identifiable on radiographs but can be accompanied by joint capsule enthesopathy on the middle phalanx (P2), which can be readily identified.
Monika A. Samol, Myra F. Barrett, David D. Frisbie   +2 more
wiley   +1 more source

Serum Leptin Exacerbates Osteoarthritis by Promoting Subchondral Bone H‐Type Vessel Angiogenesis via Activation of the PI3K/AKT Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease closely associated with obesity. Adipokines secreted by adipose tissue play critical roles in disease progression. This study focuses on the adipokine leptin and investigates its relationship with knee osteoarthritis.
Ruifu Li, Zhao Xi, Shitong Luo, Jun Qin, Tao Liu, Jian Zhang   +5 more
wiley   +1 more source

Evaluation qualitative macroscopique et microscopique du grasset chez un modèle expérimental d'arthrose canine 90 jours après section du ligament croisé crânial [PDF]

, 2013
La transection du ligament croisé crânial (CCLT) est une méthode couramment admise d'induction expérimentale d'arthrose (OA) au niveau du grasset chez le chien.
Maître, Pierre, Arnault, Fabien, Roger, Thierry, Verset, Michaël, Boulocher, Caroline, Fau, Didier, Viguier, Eric   +6 more
core  

Differential effects of alendronate on chondrocytes, cartilage matrix and subchondral bone structure in surgically induced osteoarthritis in mice

Scientific Reports
Bisphosphonates (BP) are considered a treatment option for osteoarthritis (OA) due to reduction of OA-induced microtrauma in the bone marrow, stabilization of subchondral bone (SB) layer and pain reduction.
Marianne Ehrnsperger, Shahed Taheri, Patrick Pann, Arndt F. Schilling, Susanne Grässel   +4 more
doaj   +1 more source

A New Stage and Classification of Osteonecrosis of the Femoral Head Based on MRI With Pathophysiological Interpretation

Orthopaedic Surgery, Volume 18, Issue 7, Page 1448-1458, July 2026.
An MRI‐based classification system integrating fibrosis extent (F1–F3) and inflammatory bone marrow edema activity (E0–E3) was developed for osteonecrosis of the femoral head (ONFH). Increasing fibrosis and edema severity were associated with higher collapse risk, worse pain, and poorer hip function.
Mengran Shen, Hongxu Li, Haoyang Liu, Qihan Ma, Bailiang Wang, Liming Cheng, Jinhui Ma   +6 more
wiley   +1 more source

Identical subchondral bone microarchitecture pattern with increased bone resorption in rheumatoid arthritis as compared to osteoarthritis

, 2014
SummaryObjectivesTo analyze the differences in microarchitecture and bone remodeling of subchondral bone in femoral heads from patients with rheumatoid arthritis (RA) and osteoarthritis (OA).DesignsPeri-articular bone samples, including subchondral ...
Cheng, T.S., Zheng, M.H., Landao-Bassonga, E., Zhang, C., Zheng, Q., Li, G., Pavlos, N.J., Ma, Y., Qin, A.   +8 more
core   +1 more source

Protective effects of tumor necrosis factor-α blockade by adalimumab on articular cartilage and subchondral bone in a rat model of osteoarthritis

Brazilian Journal of Medical and Biological Research, 2015
We aimed to investigate the effects of an anti-tumor necrosis factor-α antibody (ATNF) on cartilage and subchondral bone in a rat model of osteoarthritis.
C.H. Ma, Q. Lv, Y.X. Yu, Y. Zhang, D. Kong, K.R. Niu, C.Q. Yi   +6 more
doaj   +1 more source