Results 11 to 20 of about 7,584 (205)

Subchondral Bone Plate Changes More Rapidly than Trabecular Bone in Osteoarthritis [PDF]

International Journal of Molecular Sciences, 2016
Osteoarthritis (OA) is the most common joint disorder, characterised by focal loss of cartilage and increased subchondral bone remodelling at early OA stages of the disease. We have investigated the temporal and the spatial relationship between bone remodelling in subchondral bone plate (Sbp) and trabecular bone (Tb) in Dunkin Hartley (DH, develop OA ...
Zamli, Zaitunnatakhin, Robson Brown, Katharine A, Sharif, Mohammed   +2 more
openaire   +5 more sources

An integral biochemical analysis of the main constituents of articular cartilage, subchondral and trabecular bone [PDF]

Osteoarthritis and Cartilage, 2004
In articular joints, the forces generated by locomotion are absorbed by the whole of cartilage, subchondral bone and underlying trabecular bone. The objective of this study is to test the hypothesis that regional differences in joint loading are related to clear and interrelated differences in the composition of the extracellular matrix (ECM) of all ...
Harst, M.R. van der, Brama, P.A.J., Lest, C.H.A. van de, Kiers, G.H., Groot, J. de, Weeren, P.R. van   +5 more
openaire   +5 more sources

Chitosan in viscosupplementation: in vivo effect on rabbit subchondral bone

BMC Musculoskeletal Disorders, 2017
Background To investigate the effect of intra-articular injection of Chitosan (Cs) added to hyaluronic acid (HA) on subchondral bone during osteoarthritis (OA), microarchitectural parameters and mineral density were measured in a rabbit model of early OA.
R. Rieger, C. Boulocher, S. Kaderli, T. Hoc   +3 more
doaj   +2 more sources

Hemodynamic stress shapes subchondral bone in osteoarthritis: An emerging hypothesis

Journal of Orthopaedic Translation, 2022
Osteoarthritis (OA) is no longer regarded as a simple wear-and-tear problem of articular cartilage. Instead, OA is a whole joint disorder involving both cartilaginous and non-cartilaginous tissues such as subchondral bone and synovium.
Ruiyan Ni, X.Edward Guo, ChunHoi Yan, Chunyi Wen   +3 more
doaj   +2 more sources

Ontogenetic Patterning of Human Subchondral Bone Microarchitecture in the Proximal Tibia

Biology, 2022
High-resolution computed tomography images were acquired for 31 proximal human tibiae, age 8 to 37.5 years, from Norris Farms #36 cemetery site (A.D. 1300).
Jesse R. Goliath, James H. Gosman, Sam D. Stout, Timothy M. Ryan   +3 more
doaj   +2 more sources

Hip osteoarthritis: A novel network analysis of subchondral trabecular bone structures. [PDF]

PNAS Nexus, 2022
ABSTRACT Hip osteoarthritis (HOA) is a degenerative joint disease that leads to the progressive destruction of subchondral bone and cartilage at the hip joint. Development of effective treatments for HOA remains an open problem, primarily due to the lack of knowledge of its pathogenesis and a typically late-stage ...
Dorraki M, Muratovic D, Fouladzadeh A, Verjans JW, Allison A, Findlay DM, Abbott D.   +6 more
europepmc   +4 more sources

Changes in subchondral bone morphology with osteoarthritis in the ankle. [PDF]

PLoS ONE
Significant alterations to subchondral trabecular bone microarchitecture are observed in late-stage osteoarthritis (OA). However, detailed investigation of these changes to bone in the ankle are under-reported.
Lekha Koria, Mark Farndon, Elena Jones, Marlène Mengoni, Claire Brockett   +4 more
doaj   +2 more sources

Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?

Joint Diseases and Related Surgery, 2018
This study aims to investigate the role of subchondral trabecular bone thickness in the mechanism of knee osteoarthritis and the correlation of osteoarthritis and osteoporosis pathogenesis.The study included 62 patients (9 males, 53 females; mean age 66.7 years; range, 50 to 84 years) with osteoarthritis.
Mehmet Ali, Tokgöz, Osman Şahap, Atik, Güldal, Esendağlı, Betül, Öğüt, Hasan Hüseyin, Bozkurt   +4 more
openaire   +4 more sources

Tibial subchondral trabecular bone micromechanical and microarchitectural properties are affected by alignment and osteoarthritis stage. [PDF]

Sci Rep, 2020
AbstractAt advanced knee osteoarthritis (OA) stages subchondral trabecular bone (STB) is altered. Lower limb alignment plays a role in OA progression and modify the macroscopic loading of the medial and lateral condyles of the tibial plateau. How the properties of the STB relate to alignment and OA stage is not well defined.
Renault JB, Carmona M, Tzioupis C, Ollivier M, Argenson JN, Parratte S, Chabrand P.   +6 more
europepmc   +6 more sources

Brillouin micro-spectroscopy of subchondral, trabecular bone and articular cartilage of the human femoral head. [PDF]

Biomed Opt Express, 2019
Brillouin micro-spectroscopy is applied for investigating the mechanical properties of bone and cartilage tissues of a human femoral head. Distinctive mechanical properties of the cartilage surface, subchondral and trabecular bone are reported, with marked heterogeneities at both micrometric and millimetric length scales. A ubiquitous soft component is
Cardinali MA, Dallari D, Govoni M, Stagni C, Marmi F, Tschon M, Brogini S, Fioretto D, Morresi A.   +8 more
europepmc   +3 more sources