Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
A Plea for the Scientific Study of Insanity.Being the substance of addresses delivered before the Royal Academy of Medicine of Ireland, and the Medical Institution of Liverpool. By J. Batty Tuke, M. D., F. R. C. P. Edin., Medical Superintendent of the Naughton Hall Institution for the Cure and Care of the Insane. Edinburgh and London: Young J. Pentland, 1891. [Reprint from theBritish Medical Journal.] [PDF]
J. M. M.
openalex +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé+7 more
wiley +1 more source
Attitudes Towards Substance Use: A Potential Mechanism in the Relationship Between Conduct Disorder and Substance Use in Detained Youth [PDF]
poster abstractBackground: There is a well-established relationship between conduct disorder and substance use, particularly in detained youth. Attitudes toward substance use predict alcohol and marijuana use; however, little research has investigated
Aalsma, Matthew+3 more
core
Role of Substance P Neuropeptide in Inflammation, Wound Healing, and Tissue Homeostasis
S. Suvas
semanticscholar +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Effects of Ginseng Peptides on Laxative in Mice
Objective: To study the moisturizing and laxative effects of ginseng peptides (GPs) on the constipation model of ICR mice, and provide theoretical basis for the further development and utilization of GPs and clinical adjuvant treatment of constipation ...
Qiannan WANG+7 more
doaj +1 more source
Rapid Destruction of the PFS Form of Phytochrome by a Substance in Extracts of Pisum Tissue [PDF]
Masaki Furuya, William S. Hillman
openalex +1 more source
Neuropeptide substance P and the immune response
A. Mashaghi+5 more
semanticscholar +1 more source