Results 261 to 270 of about 2,039,151 (340)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Substance P in the medial amygdala regulates aggressive behaviors in male mice. [PDF]

Neuropsychopharmacology
He ZX, Yue MH, Liu KJ, Wang Y, Qiao JY, Lv XY, Xi K, Zhang YX, Fan JN, Yu HL, He XX, Zhu XJ.   +11 more
europepmc   +1 more source

Regulation by Thyroid Hormone of the Concentration of Substance P in the Rat Anterior Pituitary*

, 1984
Neil Aronin, Kathryn O. Morency, Susan E. Leeman, Lewis E. Braverman, Rafael Coslovsky   +4 more
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Substance P- and Insulin-like Growth Factor 1-derived Tetrapeptides for Neurotrophic Keratopathy Related to Leprosy: A Clinical Trial. [PDF]

Ophthalmol Sci
Kondo S, Okano Y, Iraha S, Tokunaga S.
europepmc   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

The Neuropeptide Substance P is Elevated in Sickle Cell Disease and is a Marker of Severity of Vaso-occlusive Crisis. [PDF]

Niger Med J
Olawuyi OA, Salawu L, Adeyemo MA, Bolarinwa RA, Mabayoje VO, Akerele OI.   +5 more
europepmc   +1 more source

Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli.

, 1983
Rebecca Matsas, I S Fulcher, A J Kenny, Anthony J. Turner   +3 more
openalex   +1 more source

Substance P radioimmunoassay

Japanese Journal of Pharmacology, 1977
Masanori Otsuka, Noboru Yanaihara
openaire   +2 more sources