Results 271 to 280 of about 22,248,138 (428)

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

GPR35 agonists inhibit TRPA1-mediated colonic nociception through suppression of substance P release. [PDF]

Pain
Gupta RA, Higham JP, Pearce A, Urriola-Muñoz P, Barker KH, Paine L, Ghooraroo J, Raine T, Hockley JRF, Rahman T, St John Smith E, Brown AJH, Ladds G, Suzuki R, Bulmer DC.   +14 more
europepmc   +1 more source

The influence of larval food substances on the egg maturation of Culex pipiens molestus and hybrids of C. p. molestus and C. p. pallens

, 1976
Ritsuko SATO, Kiyoshi Kamimura
openalex   +2 more sources

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Time course of the motoneuron-depolarizing action of substance P

, 1978
Mitsuhiko Yanagisawa, Toshihiko Suzue, Elizabeth Theriault, Shiro Konishi, Masanori Otsuka   +4 more
openalex   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Neuronal substance P-driven MRGPRX2-dependent mast cell degranulation products differentially promote vascular permeability. [PDF]

Front Immunol
Nagamine M, Kaitani A, Izawa K, Ando T, Yoshikawa A, Nakamura M, Maehara A, Yamamoto R, Okamoto Y, Wang H, Yamada H, Maeda K, Nakano N, Shimizu T, Ogawa H, Okumura K, Kitaura J.   +16 more
europepmc   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Exploring the relationship between plasma substance P and glottal incompetence in the elderly. [PDF]

Heliyon
Tsunoda K, Ishii T, Kuroda H, Nakatani H, Tateda M, Masuda S, Takiguchi T, Tanaka F, Misawa H, Senarita M, Takazawa M, Itoh K, Baer T.   +12 more
europepmc   +1 more source

A Light and Electron Microscopic Immunohistochemical Study of Vasoactive Intestinal Polypeptide— And Substance P-Containing Nerve Fibers along the Cerebral Blood Vessels: Comparison with Aminergic and Cholinergic Nerve Fibers

, 1984
Toru Itakura, Takashi Okuno, Kazuo Nakakita, Ichiro Kamei, Yutaka Naka, Kunio Nakai, Harumichi Imai, Norihiko Komai, Hiroshi Kimura, Toshihiro Maeda   +9 more
openalex   +1 more source