Results 41 to 50 of about 21,551,551 (367)

Substance P regulates puberty onset and fertility in the female mouse [PDF]

open access: yes, 2015
Puberty is a tightly regulated process that leads to reproductive capacity. Kiss1 neurons are crucial in this process by stimulating GnRH, yet how Kiss1 neurons are regulated remains unknown. Substance P (SP), an important neuropeptide in pain perception,
Carroll, R.S.   +7 more
core   +1 more source

Skin reaction to capsaicin in patients with Systemic Lupus Erythematosus compared to that in healthy controls

open access: yesCaspian Journal of Internal Medicine, 2021
Background: The interaction between nervous and immune systems has been under investigation. Transient receptor potential vanilloid type 1(TRPV1) is a ligand gated calcium channel expressed by sensory neurons which mediates neurogenic inflammatory ...
Maryam Sahebari   +5 more
doaj  

Activation of Microglia by Histamine and Substance P

open access: yesCellular Physiology and Biochemistry, 2014
Background: Activated microglia perform many of the immune effector functions typically associated with macrophages. However, the regulators involved in microglial activation are not well defined.
Jinato Zhu, Chen Qu, Xiang Lu, Shu Zhang
semanticscholar   +1 more source

Effects of endodontic treatment on salivary levels of CGRP and substance P: a pilot study [PDF]

open access: yesRestorative Dentistry & Endodontics, 2020
ObjectivesThe aim of this study was to evaluate the effects of endodontic treatment on levels of substance P (SP) and calcitonin gene-related peptide (CGRP) in the saliva of patients with symptomatic apical periodontitis.Materials and MethodsTwelve ...
Hakan Arslan   +2 more
doaj   +1 more source

Impulsivity in Sexual Trauma Survivors and their Use of Alcohol and Substances [PDF]

open access: yes, 2020
Impulsivity in Sexual Trauma Survivors and their Use of Alcohol and Substances Kayla McLean, Dept. of Psychology, with Dr. Jasmin Vassileva, Depts. of Psychology and Psychiatry The current study investigates the associations of neurocognitive ‘choice ...
McLean, Kayla
core   +1 more source

Substance P-expressing excitatory interneurons in the mouse superficial dorsal horn provide a propriospinal input to the lateral spinal nucleus [PDF]

open access: yes, 2018
The superficial dorsal horn (laminae I and II) of the spinal cord contains numerous excitatory and inhibitory interneurons, and recent studies have shown that each of these groups can be divided into several neurochemically distinct populations. Although
Bell, Andrew M.   +4 more
core   +1 more source

A comparison of substance use stigma and health stigma in a population of veterans with co-occurring mental health and substance use disorders [PDF]

open access: yes, 2016
OBJECTIVE: This pilot study examined whether substance use or mental illness was more stigmatizing among individuals with co-occurring mental health and substance abuse problems.
Byrne, Thomas H.   +5 more
core   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale   +6 more
wiley   +1 more source

Synthesis of new tetra- and pentacyclic, methylenedioxy- and ethylenedioxy-substituted derivatives of the dibenzo[c,f][1,2]thiazepine ring system

open access: yesBeilstein Journal of Organic Chemistry
New tetra- and pentacyclic derivatives of the dibenzo[c,f][1,2]thiazepine ring system have been synthesized. The target compounds contain methylenedioxy or ethylenedioxy substituents linked to the benzene ring.
Gábor Berecz   +5 more
doaj   +1 more source

Substance P: An Inflammatory Peptide

open access: yesEuropean Journal of Inflammation, 2008
Substance P (SP) is involved in neurogenic inflammation and in the pathogenesis of several inflammatory diseases, demonstrating that there is a narrow interrelationship between the nervous system and immunity.
G.S. Katsanos   +6 more
doaj   +1 more source

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