Results 101 to 110 of about 71,981 (295)

High-Resolution Proteomics Unravel a Native Functional Complex of Cav1.3, SK3, and Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels in Midbrain Dopaminergic Neurons

Cells
Pacemaking activity in substantia nigra dopaminergic neurons is generated by the coordinated activity of a variety of distinct somatodendritic voltage- and calcium-gated ion channels. We investigated whether these functional interactions could arise from
Maya Belghazi, Cécile Iborra, Ophélie Toutendji, Manon Lasserre, Dominique Debanne, Jean-Marc Goaillard, Béatrice Marquèze-Pouey   +6 more
doaj   +1 more source

Efficacy and Safety of Foslevodopa/Foscarbidopa Monotherapy in Patients with Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background As Parkinson's disease (PD) progresses, managing symptoms becomes increasingly difficult. Foslevodopa/foscarbidopa (LDp/CDp), a 24‐hour/day continuous subcutaneous infusion of levodopa/carbidopa (LD/CD) prodrugs, improves motor complications.
Jason Aldred, Manon Bouchard, Juan Carlos Martínez‐Castrillo, Michael J. Soileau, Amy M. Spiegel, Lars Bergmann, Resmi Gupta, Megha B. Shah, Pavnit Kukreja, David G. Standaert, Stuart H. Isaacson, Tove Henriksen   +11 more
wiley   +1 more source

Soemmerring and the Substantia Nigra [PDF]

Medical History, 1968
J. B. Carman, D. W. Taylor, R. L. M Faull   +2 more
openaire   +2 more sources

HISTOLOGICAL STUDIES ON THE INTRANUCLEAR INCLUSIONS OF THE MELANIN-PIGMENTED NERVE CELLS IN THE SUBSTANTIA NIGRA AND THE NUCLEUS LOCI CAERULEI

, 1970
Shigemi Anraku, CHISHIN MIURA, Hironori Mori, Toshiaki Fukutomi   +3 more
openalex   +2 more sources

The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method. [PDF]

, 1991
Bente Pakkenberg, Arne Møller, H.J.G. Gundersen, Agnete Mouritzen Dam, H. Pakkenberg   +4 more
openalex   +1 more source

Pathophysiological Role of Primary Motor Cortex in Essential Tremor

Movement Disorders, EarlyView.
Abstract Background Essential tremor (ET) is one of the most prevalent movement disorders. However, the complete understanding of ET pathophysiology remains elusive. Objective To explore the pathophysiological role of primary motor cortex (M1) in ET, specifically exploring its neurophysiological changes and their correlation with voluntary motor ...
Daniele Birreci, Luca Angelini, Giulia Paparella, Davide Costa, Antonio Cannavacciuolo, Massimiliano Passaretti, Martina De Riggi, Simone Aloisio, Donato Colella, Andrea Guerra, Matteo Bologna   +10 more
wiley   +1 more source

INHIBITION OF THALAMIC AND HYPOTHALAMIC SOMATOSENSORY EVOKED POTENTIALS BY STIMULATION OF SUBSTANTIA NIGRA AND ITS MODIFICATION BY MORPHINE AND METHOTRIMEPRAZINE (LEVOMEPROMAZINE)

, 1976
Hiroshi Kuromi, Masamichi Satoh, Hiroshi Takagi   +2 more
openalex   +1 more source

Ciliary neurotrophic factor prevents degeneration of adult rat substantia nigra dopaminergic neurons in vivo. [PDF]

, 1993
Theo Hagg, Silvio Varon
openalex   +1 more source

Paired Deep Brain Stimuli Elicit Short‐Term Facilitation in Globus Pallidus Interna and Subthalamic Nucleus

Movement Disorders, EarlyView.
Abstract Background Deep brain stimulation (DBS) elicits oscillatory local field potentials in patients with Parkinson's disease (PD) and other movement disorders. Greater knowledge about the fast dynamics of these neural responses could shed light on circuit pathophysiology and inform novel approaches to neuromodulation therapies.
Sarah Brinkerhoff, Arie Nakhmani, Alex Varghese, Cameron Gordon, Christopher L. Gonzalez, J. Nicole Bentley, Marshall T. Holland, Harrison C. Walker   +7 more
wiley   +1 more source

Electron Microscopic Observation of Terminal Degeneration in the Neostriatum after Destruction of the Substantia Nigra in the Rat

, 1977
Kikuko Imamoto, Nobuo Shimizu
openalex   +2 more sources