Results 111 to 120 of about 129,849 (338)

Vestibular Dysfunction in Parkinson's Disease: A Systematic Review of Signs and Symptoms

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Despite the growing interest in the link between Parkinson's disease (PD) neuropathology and vestibular system, there is still a lack of consensus about the presence of vestibular dysfunctions in PD. Objective This review aims to identify vestibular signs and symptoms reported in PD patients and to summarize and critically appraise ...
Francisco Rosado‐Martins, Beatriz Santos, Cláudia M. Costa, Tiago Eça, Raquel Bouça‐Machado, Joaquim J. Ferreira   +5 more
wiley   +1 more source

Epigenetic insights into neuropsychiatric and cognitive symptoms in Parkinson’s disease: A DNA co-methylation network analysis

npj Parkinson's Disease
Parkinson’s disease is a highly heterogeneous disorder, encompassing a complex spectrum of clinical presentation including motor, sleep, cognitive and neuropsychiatric symptoms.
Joshua Harvey, Adam R. Smith, Luke S. Weymouth, Rebecca G. Smith, Isabel Castanho, Leon Hubbard, Byron Creese, Catherine Bresner, Nigel Williams, Ehsan Pishva, Katie Lunnon   +10 more
doaj   +1 more source

OXIDATIVE STRESS-DEPENDENT ALTERED IMMUNE RESPONSES AND CELL DEATH IN SUBSTANTIA NIGRA AFTER OZONE EXPOSURE IN RAT

Frontiers in Aging Neuroscience, 2015
Parkinson’s disease has been associated with the selective loss of neurons in the substantia nigra pars compacta. Increasing evidence suggests that oxidative stress plays a major role. The resulting increase in reactive oxygen species triggers a sequence
Selva eRivas - Arancibia, Luis Fernando Hernandez - Zimbron, Ana Erika Rodriguez - Martinez, Perla eDeyanira-Maldonado, Gabino eBorgonio - Perez, Maria eSepulveda - Parada   +5 more
doaj   +1 more source

The substantia nigra in Parkinsonism. [PDF]

Journal of Clinical Pathology, 1969
S. Roy, L Wolman
openaire   +3 more sources

The action of muscimol on neurones of the substantia nigra of the rat [PDF]

, 1978
H.-R. Olpe, Werner P. Koella
openalex   +1 more source

Prognostic Value of Parkinson's Disease Subtypes in the LABS‐PD Cohort: Functional Ability, Quality of Life and Mortality

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Research on Parkinson's disease (PD) heterogeneity may inform clinical prognosis. There is currently no fully validated PD subtype classification system. Objectives We aimed at assessing the prognostic relevance of a data‐driven PD subtype classification system.
Deepa Dash, Shirley Eberly, David Oakes, David Grimes, Anthony E. Lang, Caroline Tanner, Tiago A. Mestre, Connie Marras   +7 more
wiley   +1 more source

Unilateral substantia nigra lesions and schedule-induced polydipsia [PDF]

, 1986
Guy Mittleman, Elliot S. Valenstein
openalex   +1 more source

Auditory oddball responses in the human subthalamic nucleus and substantia nigra pars reticulata

Neurobiology of Disease
The auditory oddball is a mainstay in research on attention, novelty, and sensory prediction. How this task engages subcortical structures like the subthalamic nucleus and substantia nigra pars reticulata is unclear.
Dallas Leavitt, Frhan I. Alanazi, Tameem M. Al-Ozzi, Melanie Cohn, Mojgan Hodaie, Suneil K. Kalia, Andres M. Lozano, Luka Milosevic, William D. Hutchison   +8 more
doaj   +1 more source

On the potassium conductance increase activated by GABAB and dopamine D2 receptors in rat substantia nigra neurones. [PDF]

, 1988
M.G. Lacey, Nicola Biagio Mercuri, R A North   +2 more
openalex   +1 more source

Impaired Glymphatic Clearance, Measured Using Diffusion Tensor Image Analysis Along the Perivascular Space (DTI‐ALPS), is Linked to Poor Cognitive Outcomes in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Impaired glymphatic clearance may contribute to pathological accumulations in Parkinson's (PD), but how it interacts with other processes causing dementia remains unclear. Diffusion tensor image analysis along the perivascular space (DTI‐ALPS) has been proposed as an indirect proxy for glymphatic clearance. Objectives To clarify DTI‐
Angeliki Zarkali, George Thomas, Ross Paterson, Naomi Hannaway, Ivelina Dobreva, Amanda J. Heslegrave, Elena Veleva, Henrik Zetterberg, Rimona S. Weil   +8 more
wiley   +1 more source