GM1 Ganglioside Modifies α-Synuclein Toxicity and is Neuroprotective in a Rat α-Synuclein Model of Parkinson\u27s Disease. [PDF]
, 2019 While GM1 may interact with α-synuclein in vitro to inhibit aggregation, the ability of GM1 to protect against α-synuclein toxicity in vivo has not been investigated.
Aras, Radha +5 more
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Resolution of abnormal fractional anisotropy of substantia nigra in organophosphate intoxication. C. Swinnen et al., Acta Neurologica Belgica (2011) 111:378 [PDF]
, 2012 Jan De Bleecker
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Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances
Mass Spectrometry Reviews, EarlyView.Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley +1 more source
Frontiers in Aging Neuroscience, 2015 Parkinson’s disease has been associated with the selective loss of neurons in the substantia nigra pars compacta. Increasing evidence suggests that oxidative stress plays a major role. The resulting increase in reactive oxygen species triggers a sequence
Selva eRivas - Arancibia +5 more
doaj +1 more source
Implementation of deep neural networks to count dopamine neurons in substantia nigra [PDF]
, 2018 Anna‐Maija Penttinen +8 more
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Efficacy and Safety of Foslevodopa/Foscarbidopa Monotherapy in Patients with Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.Abstract Background As Parkinson's disease (PD) progresses, managing symptoms becomes increasingly difficult. Foslevodopa/foscarbidopa (LDp/CDp), a 24‐hour/day continuous subcutaneous infusion of levodopa/carbidopa (LD/CD) prodrugs, improves motor complications.
Jason Aldred +11 more
wiley +1 more source
npj Parkinson's DiseaseParkinson’s disease is a highly heterogeneous disorder, encompassing a complex spectrum of clinical presentation including motor, sleep, cognitive and neuropsychiatric symptoms.
Joshua Harvey +10 more
doaj +1 more source
Spontaneous and Evoked Activity of Substantia Nigra Pars Reticulata Neurons during High-Frequency Stimulation of the Subthalamic Nucleus [PDF]
, 2003 Nicolas Maurice +3 more
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Vestibular Dysfunction in Parkinson's Disease: A Systematic Review of Signs and Symptoms
Movement Disorders Clinical Practice, EarlyView.Abstract Background Despite the growing interest in the link between Parkinson's disease (PD) neuropathology and vestibular system, there is still a lack of consensus about the presence of vestibular dysfunctions in PD. Objective This review aims to identify vestibular signs and symptoms reported in PD patients and to summarize and critically appraise ...
Francisco Rosado‐Martins +5 more
wiley +1 more source
How to run a brain bank. A report from the Austro-German brain bank [PDF]
, 1993 The sophisticated analysis of and growing information on the human brain requires that acquisition, dissection, storage and distribution of rare material are managed in a professional way.
Gsell, W. +9 more
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