Results 171 to 180 of about 133,054 (344)

Unilateral Magnetic Resonance‐Guided Focused Ultrasound (MRgFUS) Pallidothalamic Tractotomy in Parkinson's Disease: Promising Results But Uncertain Target

Movement Disorders, EarlyView.
Mickael Aubignat
wiley   +1 more source

Temperature Dependence of Paramagnetic Species in the Human Brain Tissue: An X‐Band EPR Study

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Paramagnetic ions are distributed throughout the human brain. The increased accumulation of these metals, such as iron and copper, can induce cellular death and the development of neurological diseases. Electron Paramagnetic Resonance (EPR) is a spectroscopic technique capable of detecting these ions in a given biological sample ...
André Avanzine, José Henrique Monteiro de Azevedo, Martina Huber, Fábio Seiji Otsuka, Maria Concepción García Otaduy, Roberta Diehl Rodriguez, Carlos Ernesto Garrido Salmon   +6 more
wiley   +1 more source

Coupling CZE, Liquid‐Phase Ion Mobility, to MS/MS for Quantitative Top‐Down Proteomics: Revealing Significant Proteoform Differences Between Healthy and Alzheimer's Disease Brains

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and pathological protein aggregation. Comprehensive quantitative proteomics of brain tissues from AD patients is critical for pursuing a better understanding of the molecular mechanisms that drive AD progression.
Mehrdad Falamarzi Askarani, Fei Fang, Scott E. Counts, Liangliang Sun   +3 more
wiley   +1 more source

Helicobacter pylori infection and α-synuclein pathology drive parallel neurodegenerative pathways in the substantia nigra. [PDF]

J Neuroinflammation
Soto-Avellaneda A, Prigent A, Meyerdirk L, Schautz N, Pospisilik JA, Brundin L, Henderson MX.   +6 more
europepmc   +1 more source

Comparison of 6‐hydroxydopamine lesions of the substantia nigra and the medial forebrain bundle on a lateralised choice reaction time task in mice

, 2012
Andreas Heuer, Gaynor A. Smith, Stephen B. Dunnett   +2 more
openalex   +2 more sources

Probing Early α‐Synuclein Oligomers: Insights Into Aggregation Pathways of NACore and preNAC Segments Probed by Trapped Ion‐Mobility Mass Spectrometry and Fluorescence Spectroscopy

PROTEOMICS, EarlyView.
ABSTRACT Misfolding and aggregation of α‐Synuclein (α‐Syn) play a central role in Parkinson's disease (PD), with oligomeric intermediates implicated as key toxic species. Here, we investigate the aggregation of two α‐Syn segments, the NACore (68GAVVTGVTAVA78, WT‐PD1) and the preNAC region (47GVVHGVATVA56, WT‐PD2), using high‐resolution trapped ion ...
Agathe Depraz Depland, Stephanie Mikromanolis, Iuliia Stroganova, Anouk M. Rijs   +3 more
wiley   +1 more source

Deep-learning segmentation of the substantia nigra from multiparametric MRI: Application to Parkinson's disease. [PDF]

Imaging Neurosci (Camb)
Lillebostad PAG, Njølstad TH, Hogstad S, Riemer F, Kverneng SU, Stige KE, Biermann M, Jog M, Buch S, Haacke EM, Tzoulis C, Lundervold A.   +11 more
europepmc   +1 more source

Dopamine Modulates Striato-Frontal Functioning during Temporal Processing [PDF]

, 2011
Jahanshahi, Marjan, Jones, Catherine RG
core   +3 more sources

Multi‐Channel Neural Interface for Neural Recording and Neuromodulation

Small Methods, EarlyView.
This review highlights recent advances in multi‐channel neural interface technologies, covering both high‐resolution electrophysiological recording systems and multifunctional platforms with integrated capabilities. It also discusses innovations in structure and materials for reduced invasiveness, state‐of‐the‐art data analysis, including machine ...
Eunmin Kim, Won Gi Chung, Enji Kim, Myoungjae Oh, Joonho Paek, Taekyeong Lee, Dayeon Kim, Seung Hyun An, Sumin Kim, Jang‐Ung Park   +9 more
wiley   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study. [PDF]

Adv Biol (Weinh)
Eggers B, Hausherr M, Lim M, Schork K, Karacora B, Grugel R, Eisenacher M, Aldea IG, Riederer P, Gerlach M, Marcus K.   +10 more
europepmc   +1 more source