Results 171 to 180 of about 76,030 (307)

Intraarterial microbubble delivery enhances focused ultrasound induced blood brain barrier opening in the murine substantia nigra. [PDF]

Sci Rep
Li H, Lee YH, Zen X, Huang MW, Liu CW, Ho EP, Ou-Yang CH, Lin HI, Chen CA, Chang YY, Liu HL, Lin CH.   +11 more
europepmc   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

Japanese Encephalitis: Characteristic Imaging in Substantia Nigra, Thalamus, and Basal Ganglia. [PDF]

Intern Med
Sekiguchi K, Sawada J, Anan Y, Fujimoto S.   +3 more
europepmc   +1 more source

Evidence for Dopamine Abnormalities in the Substantia Nigra in Cocaine Addiction Revealed by Neuromelanin-Sensitive MRI

, 2020
Clifford Cassidy, Kenneth M. Carpenter, Anna B. Konova, Victoria Cheung, Alexander Grassetti, Luigi Zecca, Anissa Abi‐Dargham, Diana Martinez, Guillermo Horga   +8 more
openalex   +2 more sources

Axon Initial Segment: Structure, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 4, April 2026.
The axon initial segment (AIS) is a specialized axonal domain critical for maintaining neuronal polarity, action potential initiation, and network stability. This review summarizes the necessary elements for maintaining AIS structure and plasticity, discussing crucial biological functions of AIS in neuronal signaling and the neural circuit homeostasis,
Dong‐Yan Song, Lin Yuan, Weiguo Yang, Wen Li, Jia‐Yi Li   +4 more
wiley   +1 more source

Glial cell-specific proteomic data from the substantia nigra of a rat 6-OHDA and fluorocitrate model of astrocyte death and microglial activation. [PDF]

Data Brief
Kadłuczka J, Chubukova T, Mielczarek P, Maziak A, Roman A, Napieralska E, Kuter KZ.   +6 more
europepmc   +1 more source

Quantitative Susceptibility Mapping in Skull Base Chordoma: In Silico Analysis and In Vivo Application Towards Indirect Hypoxia Assessment

Magnetic Resonance in Medicine, Volume 95, Issue 4, Page 2092-2105, April 2026.
ABSTRACT Purpose To evaluate quantitative susceptibility mapping (QSM) beyond the brain through realistic simulations and to explore preliminary evidence that may be indicative of hypoxia in skull base chordomas (SBC). Methods Each step of the QSM pipeline was optimized within an in silico framework consisting of (i) phase unwrapping, (ii) background ...
P. Fenech, L. Morelli, G. Parrella, S. Imparato, A. Iannalfi, S. Lillo, E. Orlandi, G. Baroni, C. Paganelli   +8 more
wiley   +1 more source

The spatial landscape of glial pathology and T cell response in Parkinson's disease substantia nigra. [PDF]

Nat Commun
Ma M, Paryani F, Jakubiak K, Xia S, Antoku S, Kannan A, Lee J, Madden N, Senthil Kumar S, Li J, Chen D, Hargus G, Mahajan A, Flowers X, Harms AS, Sulzer D, Goldman JE, Sims PA, Al-Dalahmah O.   +18 more
europepmc   +1 more source

Adenosinergic Protection of Dopaminergic and GABAergic Neurons against Mitochondrial Inhibition through Receptors Located in the Substantia Nigra and Striatum, Respectively [PDF]

, 2003
Peter D. Alfinito, Sheng-Ping Wang, Lawrence Manzino, Sonia Rijhsinghani, Gail D. Zeevalk, Patricia K. Sonsalla   +5 more
openalex   +1 more source

Toxic mechanisms of amyloid oligomers and therapeutic strategies

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Amyloid oligomers are increasingly recognized as the major toxic contributors across protein‐misfolding disorders. In this review, we cover mechanistic evidence showing how these transient and structurally heterogeneous oligomers disrupt cellular homeostasis by: (i) permeabilizing lipid membranes and forming ion‐conducting pores; (ii ...
Magdalena I. Ivanova, Carmelo La Rosa, Ayyalusamy Ramamoorthy   +2 more
wiley   +1 more source