Results 171 to 180 of about 71,981 (295)

Contribution of α‐synuclein cytopathologies to distinct seeding of misfolded α‐synuclein

Brain Pathology, EarlyView.
This study investigated whether brain regions with distinct predominance of α‐synuclein (αSyn) cytopathologies show different αSyn seeding patterns in multiple system atrophy (MSA) and Lewy body disease (LBD), using an interdisciplinary approach. High seeding activity is observed in regions with oligodendrocytic‐predominant αSyn pathology in MSA.
Ain Kim, Ivan Martinez‐Valbuena, Krisztina Danics, Shelley L. Forrest, Gabor G. Kovacs   +4 more
wiley   +1 more source

Release and Uptake Rates of 5‐Hydroxytryptamine in the Dorsal Raphe and Substantia Nigra Reticulata of the Rat Brain

, 1998
Melissa A. Bunin, Cassandra Prioleau, Richard B. Mailman, R. Mark Wightman   +3 more
openalex   +1 more source

Interactions of Oligodendrocyte Precursor Cells and Dopaminergic Neurons in the Mouse Substantia Nigra. [PDF]

J Neurochem
Fitzgerald JC, Sun Y, Reinecke F, Bauer E, Garaschuk O, Kahle PJ, Pfeiffer F.   +6 more
europepmc   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

Controversies about iron in parkinsonian and control substantia nigra

, 1997
J. Gała̧zka‐Friedman, Andrzej Friedman   +1 more
openalex   +2 more sources

Activation of Group I Metabotropic Glutamate Receptors Produces a Direct Excitation and Disinhibition of GABAergic Projection Neurons in the Substantia Nigra Pars Reticulata [PDF]

, 2001
Michael J. Marino, Marion Wittmann, Stefania Risso Bradley, George W. Hubert, Yoland Smith, P. Jeffrey Conn   +5 more
openalex   +1 more source

Cannabidiol dose dependently reduces alcohol intake in mice via a non‐5‐HT1A receptor mechanism: Exploration of other potential receptor targets

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Binge drinking is a risky pattern of alcohol intake and a major predictor of alcohol use disorder (AUD). Current AUD medications have limited efficacy and poor patient compliance, calling for more effective therapeutics.
Connie J. Badolato, Erin A. Lynch, Jonathon C. Arnold, Iain S. McGregor, Michael T. Bowen   +4 more
wiley   +1 more source

Modulation of cardiac activity by tachykinins in the rat substantia nigra [PDF]

, 2001
Andrée Lessard, Réjean Couture
openalex   +1 more source

Experimental Parkinsonism induced by tetanus toxin injected into basal ganglia

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Local inhibitory circuits and long‐range inhibitory projections within the interconnected basal ganglia nuclei are critical for control of voluntary movement and pathophysiology of different extrapyramidal movement disorders.
Patrik Meglić, Petra Šoštarić, Davor Virag, Ana Knezović, Nikola Habek, Ornella Rossetto, Ivica Matak   +6 more
wiley   +1 more source

Differential audiogenic seizure sensitization by selective unilateral substantia nigra lesions in resistant Wistar rats

, 1995
Maria Carolina Doretto, Norberto García-Cairasco   +1 more
openalex   +1 more source