Results 181 to 190 of about 132,532 (337)

Vesicular glutamate transporter VGLUT2 expression emerges in substantia nigra dopamine neurons in mouse models of parkinsonism in the absence of neurodegeneration

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Subsets of midbrain dopamine (DA) neurons express the vesicular glutamate transporter VGLUT2 and can release the excitatory neurotransmitter glutamate. VGLUT2+ DA neurons of the substantia nigra pars compacta (SNc) were shown to be more resistant to neurodegeneration in animal models of Parkinson's disease (PD ...
Sivakumar Srinivasan   +2 more
wiley   +1 more source

Deep-learning segmentation of the substantia nigra from multiparametric MRI: Application to Parkinson's disease. [PDF]

open access: yesImaging Neurosci (Camb)
Lillebostad PAG   +11 more
europepmc   +1 more source

Mapping Alzheimer's disease heterogeneity with molecular imaging biomarkers

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
This review outlines positron emission tomography (PET) biomarkers used in Alzheimer's disease (AD) research and clinical settings, targeting both specific (amyloid, tau) and non‐specific (neurodegeneration, synaptic density, neuroinflammation) processes.
Elif Harput   +6 more
wiley   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study. [PDF]

open access: yesAdv Biol (Weinh)
Eggers B   +10 more
europepmc   +1 more source

Effects of cell therapy on seizures in animal models of epilepsy: Systematic review and meta‐analysis

open access: yesEpilepsia, EarlyView.
Abstract This study was undertaken to systematically evaluate the efficacy of cell therapy in reducing seizures in animal models of chronic epilepsy. Three databases, Ovid MEDLINE, Ovid Embase, and Web of Science, were searched using predetermined eligibility criteria.
Afaf S. Altalhi   +6 more
wiley   +1 more source

Clinical and Genetic Characteristics of Parkinson's Disease Patients with Substantia Nigra Hyperechogenicity. [PDF]

open access: yesInt J Mol Sci
Milanowski Ł   +5 more
europepmc   +1 more source

Restoring failed inhibition in the substantia nigra pars reticulata suppresses absence seizures in rats

open access: yesEpilepsia, EarlyView.
Abstract Objective For over four decades, the substantia nigra pars reticulata (SNr) has been recognized as a critical structure in the modulation of seizure activity. Pharmacological and optogenetic inhibition of the SNr produces robust seizure suppression in a range of seizure models.
Devin Palmer, Patrick A. Forcelli
wiley   +1 more source

THE SUBSTANTIA NIGRA SOEMERINGI [PDF]

open access: yesThe Journal OF Nervous and Mental Disease, 1909
Julius Bauer, M. J. KARPAS
openaire   +1 more source

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