Results 191 to 200 of about 132,532 (337)

Transcriptional regulation of human NMNAT2: insights from 3D genome sequencing and bioinformatics

The FEBS Journal, EarlyView.
NMNAT2 is a valuable drug target, as low levels increase the risk of neurodegeneration. We employed 4C‐seq to identify NMNAT2 regulatory regions in the human genome, revealing distinct interactomes of the NMNAT2 promoter in undifferentiated and neuron‐like SH‐SY5Y cells. Additionally, we uncovered NMNAT2‐associated genes and transcription factors. This
Yu Chen Chang, Sen Yang, Minyoung Cho, Kwangsik Nho, José‐Manuel Baizabal, Hui‐Chen Lu   +5 more
wiley   +1 more source

Intraarterial microbubble delivery enhances focused ultrasound induced blood brain barrier opening in the murine substantia nigra. [PDF]

Sci Rep
Li H, Lee YH, Zen X, Huang MW, Liu CW, Ho EP, Ou-Yang CH, Lin HI, Chen CA, Chang YY, Liu HL, Lin CH.   +11 more
europepmc   +1 more source

Spontaneous bodily rotations and direction of locomotion at different times after radio frequency lesions at sites in and near the substantia nigra

, 1988
Robert L. Isaacson, Anne M. Danks, A.B. Oestreicher, Jan H. Brakkee, W.H. Gispen   +4 more
openalex   +2 more sources

Compound action potentials recorded in the ventral tegmental area, substantia nigra, and periaqueductal gray following rewarding stimulation of the lateral hypothalamus in the rat [PDF]

, 1990
Iván Kiss, Peter Shizgal
openalex   +1 more source

How artificial intelligence is shaping neuropsychology: A focus on cognitive assessment of neurodegenerative disorders

Journal of Neuropsychology, EarlyView.
Abstract Artificial intelligence (AI) and machine learning (ML) algorithms are revolutionising the world, and they have the potential to revolutionise neuropsychology as well. A particularly fruitful field for this revolution is the cognitive assessment of neurodegenerative disorders, such as Alzheimer's disease, Parkinson's disease, Mild Cognitive ...
Michele Scandola, Maria Esposito, Riccardo Guidotti, Daniele Romano   +3 more
wiley   +1 more source

Neuromelanin-targeted ¹⁸F-P3BZA PET/MR imaging of the substantia nigra in rhesus macaques. [PDF]

EJNMMI Res
Feng H, Tu N, Wang K, Ma X, Zhang Z, Liu Z, Cheng Z, Bu L.   +7 more
europepmc   +1 more source

Vesicular monoamine transporter 2 (VMAT2) overexpression in inferior colliculus (IC)-innervated substantia nigra compacta (SNc) dopaminergic neurons ameliorates noise exposure-induced 6-hydroxydopamine (6-OHDA) vulnerability.

Chi Cui (10201007), Yibo Yao (16274454), Yulong Shi (459712), Jie Lei (579923), Kun Ren (6173954), Kexing Wan (6258182), Tongxia Li (13354935), Gangan Luo (16999848), Qian Xu (119888), Ming Li (91180), Xiang Peng (3092073), Xueke Yang (14648669), Jian Yang (12136), Junsong Du (22559804), Sitong Chen (170590), Bo Tian (625365), Pei Zhang (232846)   +16 more
openalex   +1 more source

Muscarinic receptor-mediated inhibition of dopaminergic excitatory input to caudate neurons from the substantia nigra.

, 1988
Hidehiko Nabatame, Masashi Sasa, Shuji Takaori, Masakuni Kameyama   +3 more
openalex   +1 more source

The Effect of Deep Brain Stimulation on Sleep and Cognition in Patients With Parkinson's Disease

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep–wake disturbances and cognitive decline are among the most common nonmotor symptoms of Parkinson's disease (PD). Deep brain stimulation (DBS) can successfully alleviate motor symptoms. However, the impact on sleep–wake disturbances and cognitive decline, and their interaction, is yet unclear.
Monique E. H. Valk‐Geuke, Gert J. Geurtsen, Rob M. A. de Bie, Rick Schuurman, Martijn Beudel, Esmée Verwijk   +5 more
wiley   +1 more source

Synergetic effect of a DSP4-induced locus coeruleus lesion and systemic LPS exacerbates substantia nigra dopaminergic neuron loss. [PDF]

Sci Rep
Şimşek F, Papová D, Henriksson E, Olmedo-Díaz S, Blyberg M, El-Habta R, Virel A, Af Bjerkén S.   +7 more
europepmc   +1 more source