Results 201 to 210 of about 123,595 (337)

Cannabidiol dose dependently reduces alcohol intake in mice via a non‐5‐HT1A receptor mechanism: Exploration of other potential receptor targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Binge drinking is a risky pattern of alcohol intake and a major predictor of alcohol use disorder (AUD). Current AUD medications have limited efficacy and poor patient compliance, calling for more effective therapeutics.
Connie J. Badolato   +4 more
wiley   +1 more source

Activation of Group I Metabotropic Glutamate Receptors Produces a Direct Excitation and Disinhibition of GABAergic Projection Neurons in the Substantia Nigra Pars Reticulata [PDF]

open access: bronze, 2001
Michael J. Marino   +5 more
openalex   +1 more source

Experimental Parkinsonism induced by tetanus toxin injected into basal ganglia

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Local inhibitory circuits and long‐range inhibitory projections within the interconnected basal ganglia nuclei are critical for control of voluntary movement and pathophysiology of different extrapyramidal movement disorders.
Patrik Meglić   +6 more
wiley   +1 more source

The Aging Substantia Nigra is Characterized by ROS Accumulation Potentially Resulting in Increased Neuroinflammation and Cytoskeletal Remodeling. [PDF]

open access: yesAdv Biol (Weinh)
Eggers B   +10 more
europepmc   +1 more source

Attenuation of Paraquat-Induced Dopaminergic Toxicity on the Substantia Nigra by (−)-Deprenyl in Vivo [PDF]

open access: green, 2001
Horng‐Huei Liou   +4 more
openalex   +1 more source

The Application of Polymeric Nanoparticles as Drug Delivery Carriers to Cells in Neurodegenerative Diseases

open access: yesCell Proliferation, EarlyView.
Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin   +4 more
wiley   +1 more source

Aging and MPTP Sensitivity Depend on Molecular and Ultrastructural Signatures of Astroglia and Microglia in Mice Substantia Nigra. [PDF]

open access: yesCell Mol Neurobiol
Abhilash PL   +7 more
europepmc   +1 more source

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