Results 201 to 210 of about 133,054 (344)

The spatial landscape of glial pathology and T cell response in Parkinson's disease substantia nigra. [PDF]

Nat Commun
Ma M, Paryani F, Jakubiak K, Xia S, Antoku S, Kannan A, Lee J, Madden N, Senthil Kumar S, Li J, Chen D, Hargus G, Mahajan A, Flowers X, Harms AS, Sulzer D, Goldman JE, Sims PA, Al-Dalahmah O.   +18 more
europepmc   +1 more source

Matsupexole: A novel nonergot dopamine receptor agonist with sustained efficacy in a rat model of Parkinson's disease and limited off‐target activity

British Journal of Pharmacology, EarlyView.
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki, Fumiki Oana, Masaki Oota, Yuma Handa, Osamu Kaminuma   +4 more
wiley   +1 more source

Transcranial Sonographic Characteristics of Substantia Nigra in End-Stage Renal Disease Patients with Restless Legs Syndrome: A Diagnostic Marker Study. [PDF]

Diagnostics (Basel)
Wang C, Zhan Z, Ding C, Zhang Y, Luo W.
europepmc   +1 more source

The Effect of Environmental Enrichment on Substantia Nigra Gene Expression after Traumatic Brain Injury in Rats

, 2012
Samuel S. Shin, James W. Bales, Hong Q. Yan, Anthony E. Kline, Amy K. Wagner, James Lyons‐Weiler, C. Edward Dixon   +6 more
openalex   +2 more sources

Effects of cell therapy on seizures in animal models of epilepsy: Systematic review and meta‐analysis

Epilepsia, EarlyView.
Abstract This study was undertaken to systematically evaluate the efficacy of cell therapy in reducing seizures in animal models of chronic epilepsy. Three databases, Ovid MEDLINE, Ovid Embase, and Web of Science, were searched using predetermined eligibility criteria.
Afaf S. Altalhi, Muhammad S. Javaid, Nigel C. Jones, Kim L. Powell, Patrick Kwan, Terence J. O'Brien, Ana Antonic‐Baker   +6 more
wiley   +1 more source

Evaluating Parkinson's disease biomarkers in substantia nigra following sublethal γ-radiation exposure in a large animal model. [PDF]

NPJ Parkinsons Dis
Murphy EK, Perl DP, Day RM, Iacono D.
europepmc   +1 more source

Cellular properties of convulsant-treated rat neo-cortical neurons during postnatal development [PDF]

, 1989
Hablitz, John H., Kellaway, Peter, Noebels, Jeffrey L., Sutor, Bernd   +3 more
core   +1 more source

Faculty Opinions recommendation of Firing properties and functional connectivity of substantia nigra pars compacta neurones recorded with a multi-electrode array in vitro.

, 2010
Antonio Pisani, Giuseppe Sciamanna, Enza Maria Valente   +2 more
openalex   +2 more sources

Adenosinergic Protection of Dopaminergic and GABAergic Neurons against Mitochondrial Inhibition through Receptors Located in the Substantia Nigra and Striatum, Respectively [PDF]

, 2003
Peter D. Alfinito, Sheng-Ping Wang, Lawrence Manzino, Sonia Rijhsinghani, Gail D. Zeevalk, Patricia K. Sonsalla   +5 more
openalex   +1 more source

Restoring failed inhibition in the substantia nigra pars reticulata suppresses absence seizures in rats

Epilepsia, EarlyView.
Abstract Objective For over four decades, the substantia nigra pars reticulata (SNr) has been recognized as a critical structure in the modulation of seizure activity. Pharmacological and optogenetic inhibition of the SNr produces robust seizure suppression in a range of seizure models.
Devin Palmer, Patrick A. Forcelli
wiley   +1 more source