Results 211 to 220 of about 71,981 (295)

Pathways underlying selective neuronal vulnerability in Alzheimer's disease: Contrasting the vulnerable locus coeruleus to the resilient substantia nigra. [PDF]

Alzheimers Dement
Ehrenberg AJ, Sant C, Pereira FL, Li SH, Buxton J, Langlois S, Trinidad M, Oh I, Leite REP, Rodriguez RD, Paes VR, Pasqualucci CA, Seeley WW, Spina S, Suemoto CK, Temple S, Kaufer D, Grinberg LT.   +17 more
europepmc   +1 more source

Orexinergic neurons contribute to autonomic cardiovascular regulation for locomotor exercise

The Journal of Physiology, EarlyView.
Abstract figure legend This study unveiled the essential role of the orexinergic nervous system in the central circuitry that transmits central command signals for locomotor exercise. We observed the excitation of orexinergic neurons by voluntary locomotor exercise in rats.
Emi Narai, Yuki Yoshimura, Takaho Honaga, Hiroyuki Mizoguchi, Akihiro Yamanaka, Takeshi Y. Hiyama, Tatsuo Watanabe, Satoshi Koba   +7 more
wiley   +1 more source

Evaluation of Substantia Nigra morphology in Parkinson's Disease. [PDF]

Medicine (Baltimore)
Durmaz Çelik N, Yaman Kula A, Toprak U, Saylısoy S, Topal A, Özkan S.   +5 more
europepmc   +1 more source

GluN2C/D‐containing NMDA receptors enhance temporal summation and increase sound‐evoked and spontaneous firing in the inferior colliculus

The Journal of Physiology, EarlyView.
Abstract figure legend Here, we find that GluN2D‐containing NMDA receptors (NMDARs) are expressed by most vasoactive intestinal peptide neurons in the inferior colliculus (IC). These receptors are less susceptible to Mg2+ blockade compared to GluN2A/B‐containing NMDARs, allowing ions to flow at resting membrane potential.
Audrey C. Drotos, Rachel L. Zarb, Victoria Booth, Michael T. Roberts   +3 more
wiley   +1 more source

Substantia nigra alterations in mice modeling Parkinson's disease. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Rozhkova IN, Okotrub SV, Brusentsev EY, Rakhmanova TA, Lebedeva DA, Kozeneva VS, Shavshaeva NA, Khotskin NV, Amstislavsky SY.   +8 more
europepmc   +1 more source

Recent optical approaches for anatomical and functional dissection of neuron–astrocyte circuitry

The Journal of Physiology, EarlyView.
Abstract figure legend This review summarises novel optical approaches to deciphering structural and functional wiring diagrams of neuron–astrocyte circuits in the brain. There are three groups: the anatomical proximity assay, transsynaptic viral tracing and the functional connection assay. The FRET‐based neuron–astrocyte proximity assay allows mapping
Yoshiki Hatashita, Takafumi Inoue
wiley   +1 more source

Evidence for direct dopaminergic connections between substantia nigra pars compacta and thalamus in young healthy humans. [PDF]

Front Neural Circuits
Cirillo G, Caiazzo G, Franza F, Cirillo M, Papa M, Esposito F.   +5 more
europepmc   +1 more source

Characterization of NTS‐to‐VTA projection neurons reveals higher‐order synaptic organization and distinct responsiveness to cholecystokinin

The Journal of Physiology, EarlyView.
Abstract figure legend Here we construct an anatomical map of brainstem projections to the ventral tegmental area (VTA) and investigate the neurochemical and neurophysiological nature of these VTA‐projecting nucleus of the solitary tract (NTS) neurons.
Caitlin R. Ritchey, David J. Rossi, James H. Peters   +2 more
wiley   +1 more source

Retraction Note: Neuromelanin-targeted 18 F-P3BZA PET/MR imaging of the substantia nigra in rhesus macaques. [PDF]

EJNMMI Res
Feng H, Tu N, Wang K, Ma X, Zhang Z, Liu Z, Cheng Z, Bu L.   +7 more
europepmc   +1 more source

Microglial Activation and Inflammatory Responses in Parkinson's Disease Models Are Attenuated by TRPM2 Depletion

Glia, Volume 73, Issue 10, Page 2035-2056, October 2025.
Main Points Trpm2 partial and complete knockout reduce neuroinflammation in male and female mice. Microglial morphological changes are not found in Trpm2 knockout 6‐OHDA‐induced mice. TRPM2 is involved in microglial phagocytosis and IL1β, IL6, and iNOS expression. ABSTRACT Inflammation, and particularly microglial cells, has become a central feature in
Ana Flávia F. Ferreira, Zhong‐Ping Feng, Hong‐Shuo Sun, Luiz Roberto G. Britto   +3 more
wiley   +1 more source