Results 211 to 220 of about 133,054 (344)

GDNF receptor GFRα1 is necessary for the maintenance of dopaminergic neurons in the adult substantia nigra. [PDF]

PLoS One
Carrier-Ruiz A, Andersson A, Fernández-Suárez D, Ibáñez CF.   +3 more
europepmc   +1 more source

Transcriptional Regulation of Alpha-synuclein by GATA2 in Substantia Nigra [PDF]

, 2012
Max Horowitz
openalex  

Transcriptional regulation of human NMNAT2: insights from 3D genome sequencing and bioinformatics

The FEBS Journal, EarlyView.
NMNAT2 is a valuable drug target, as low levels increase the risk of neurodegeneration. We employed 4C‐seq to identify NMNAT2 regulatory regions in the human genome, revealing distinct interactomes of the NMNAT2 promoter in undifferentiated and neuron‐like SH‐SY5Y cells. Additionally, we uncovered NMNAT2‐associated genes and transcription factors. This
Yu Chen Chang, Sen Yang, Minyoung Cho, Kwangsik Nho, José‐Manuel Baizabal, Hui‐Chen Lu   +5 more
wiley   +1 more source

Neuromelanin Contrast Optimization and Improved Visualization of the Substantia Nigra in a 3D Gradient-Echo Sequence With Magnetization Transfer. [PDF]

NMR Biomed
Andikoetxea BG, Martín-Bastida A, Vidorreta M, Rodríguez-Oroz MC, Soustelle L, Troalen T, Fernández-Seara MA.   +6 more
europepmc   +1 more source

Seven tesla MRI of the substantia nigra in patients with rapid eye movement sleep behavior disorder

, 2017
Daniela Frosini, Mirco Cosottini, Graziella Donatelli, Mauro Costagli, Laura Biagi, Claudio Pacchetti, Michele Terzaghi, Pietro Cortelli, Dario Arnaldi, Enrica Bonanni, Michela Tosetti, Ubaldo Bonuccelli, Roberto Ceravolo   +12 more
openalex   +2 more sources

How artificial intelligence is shaping neuropsychology: A focus on cognitive assessment of neurodegenerative disorders

Journal of Neuropsychology, EarlyView.
Abstract Artificial intelligence (AI) and machine learning (ML) algorithms are revolutionising the world, and they have the potential to revolutionise neuropsychology as well. A particularly fruitful field for this revolution is the cognitive assessment of neurodegenerative disorders, such as Alzheimer's disease, Parkinson's disease, Mild Cognitive ...
Michele Scandola, Maria Esposito, Riccardo Guidotti, Daniele Romano   +3 more
wiley   +1 more source

Correction: Distinct spatial transcriptomic patterns of substantia Nigra in Parkinson disease and Parkinsonian subtype of multiple system atrophy. [PDF]

Acta Neuropathol Commun
Shin JH, Ruhno KE, Shin C, Kim HJ, Nam SJ, Chung SJ, Moon JH, Kim HJ.   +7 more
europepmc   +1 more source

The Effect of Deep Brain Stimulation on Sleep and Cognition in Patients With Parkinson's Disease

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep–wake disturbances and cognitive decline are among the most common nonmotor symptoms of Parkinson's disease (PD). Deep brain stimulation (DBS) can successfully alleviate motor symptoms. However, the impact on sleep–wake disturbances and cognitive decline, and their interaction, is yet unclear.
Monique E. H. Valk‐Geuke, Gert J. Geurtsen, Rob M. A. de Bie, Rick Schuurman, Martijn Beudel, Esmée Verwijk   +5 more
wiley   +1 more source

Corticonigral projections recruit substantia nigra pars lateralis dopaminergic neurons for auditory threat memories. [PDF]

Nat Commun
Sansalone L, Twedell EL, Evans RC, Boronat-Garcia A, Zhang R, Khaliq ZM.   +5 more
europepmc   +1 more source

Globus Pallidus Iron Relates to Cognitive Impairment in Alzheimer's Disease: Evidence From MRI‐Based Meta‐Analysis

Annals of the New York Academy of Sciences, EarlyView.
Iron is crucial for brain functioning, but excessive levels can harm brain health. While previous studies support this, meta‐analytic evidence in Alzheimer's disease (AD) is limited. We performed a meta‐analysis of 23 MRI studies with 715 AD patients and 1130 healthy controls.
Marthe Mieling, Clara Wiskow, Nico Bunzeck   +2 more
wiley   +1 more source