Results 221 to 230 of about 132,532 (337)

Patient Agitation in the Intensive Care Unit: A Concept Analysis

Journal of Advanced Nursing, Volume 82, Issue 2, Page 1737-1749, February 2026.
ABSTRACT Aim Exploring the concept of patient agitation in the intensive care unit. Background Patient agitation in the intensive care unit is of widespread concern and linked to negative outcomes for patients, staff, and family members. There is currently no consensus on what constitutes agitation in the intensive care context, hindering effective and
Anne Mette N. Adams, Diane Chamberlain, Charlotte Brun Thorup, Matthew J. Maiden, Cherie Waite, Hila Ariela Dafny, Kay Bruce, Tiffany Conroy   +7 more
wiley   +1 more source

Distinct spatial transcriptomic patterns of substantia Nigra in Parkinson disease and Parkinsonian subtype of multiple system atrophy. [PDF]

Acta Neuropathol Commun
Shin JH, Ruhno KE, Shin C, Kim HJ, Nam SJ, Chung SJ, Moon JH, Kim HJ.   +7 more
europepmc   +1 more source

Purkinje Cell Loss in Essential Tremor: Collective Data From 215 Brains Over a 21‐Year Period

Annals of Clinical and Translational Neurology, Volume 13, Issue 1, Page 36-48, January 2026.
ABSTRACT Objective Essential tremor is a highly prevalent movement disorder. Pathological changes observed in essential tremor cerebella center around Purkinje cells and neighboring neuronal populations. Postmortem studies have variably, but not always, shown reduced Purkinje cell counts in essential tremor compared to controls.
Chloë A. Kerridge, Roberto S. Hernandez, Nora C. Hernandez, Phyllis L. Faust, Elan D. Louis   +4 more
wiley   +1 more source

The Discovery of Phages in the Substantia Nigra and Its Implication for Parkinson's Disease. [PDF]

Research (Wash D C)
Zhao Y, Xiong C, Wang B, Li D, Liu J, Wei S, Hou Y, Zhou Y, Zheng R.   +8 more
europepmc   +1 more source

Control of oro-fasio-ligual movements by the substantia nigra pars reticulata : High-requency electrical microstimulation and GABA microinjection findings in rats

, 2005
朴 寅出
openalex   +2 more sources

Bilobalide inhibits 6-OHDA-induced activation of NF-κB and loss of dopaminergic neurons in rat substantia nigra [PDF]

, 2008
Lingyun Li, Xilin Zhao, Xi-feng Fei, Zhen‐Lun Gu, Zheng‐Hong Qin, Zhong‐Qin Liang   +5 more
openalex   +1 more source

Associations between metabolic syndrome and regional brain iron depositions and cognitive function in middle‐aged and older adults: A two multinational cohort study

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION The alterations of regional brain iron in patients with metabolic syndrome (Mets) and its relationship with cognitive function remain unclear. METHODS These analyses utilized data from two prospective cohorts, from the UK Biobank (UKB) (21,346 participants) and from Jinan, China (224 participants). We capitalized brain iron in the
Xinyue Zhang, Linfeng Yang, Na Wang, Yuanyuan Wang, Qihao Zhang, Zhenyu Cheng, Yiwen Chen, Pengcheng Liang, Meng Li, Lingfei Guo, Changhu Liang   +10 more
wiley   +1 more source

EEG Microstates Are Associated with Motor Function in Parkinson's Disease: A Cross‐Sectional Observational Study

Brain and Behavior, Volume 16, Issue 1, January 2026.
Parkinson's disease patients exhibited distinct abnormalities in microstate D, including increased mean coverage, mean duration, and incoming transition probabilities. Notably, both the coverage of microstate D and the transition probability from microstate B to D correlated with motor symptom severity, suggesting their potential as biomarkers for ...
Jiayu Cai, Yuqing Zhao, Jian Song, Xianling Xu, Jinfeng Xu, Haoran Shi, Wei Wei, Xiehua Xue   +7 more
wiley   +1 more source

Effect of age on substantia nigra subregions using neuromelanin-sensitive magnetic resonance imaging overlapping on quantitative susceptibility mapping. [PDF]

Quant Imaging Med Surg
Kuang C, Liu WV, Li L, Liu C, Zha Y.
europepmc   +1 more source

Subcortical Brain‐Age Gaps Reveal Asymmetric Aging Patterns in Parkinson's Disease With Cognitive Impairment

Brain and Behavior, Volume 16, Issue 1, January 2026.
Accelerated brain aging in Parkinson's disease is not global but a localized, asymmetric process in the left limbic‐cholinergic network. Regional brain‐age metrics offer a sensitive biomarker for detecting the specific neurodegeneration linked to cognitive decline.
Sadegh Ghaderi, Ali Fathi Jouzdani, Ali Mohammad Pourbagher‐Shahri, Sana Mohammadi   +3 more
wiley   +1 more source