Results 221 to 230 of about 133,054 (344)

Distinct spatial transcriptomic patterns of substantia Nigra in Parkinson disease and Parkinsonian subtype of multiple system atrophy. [PDF]

Acta Neuropathol Commun
Shin JH, Ruhno KE, Shin C, Kim HJ, Nam SJ, Chung SJ, Moon JH, Kim HJ.   +7 more
europepmc   +1 more source

Decision letter: Correct setup of the substantia nigra requires Reelin-mediated fast, laterally-directed migration of dopaminergic neurons

, 2018

openalex   +1 more source

Modulation of dopamine efflux in the striatum following cholinergic stimulation of the substantia nigra in intact and pedunculopontine tegmental nucleus-lesioned rats [PDF]

, 1993
Charles D. Blaha, Philip Winn
openalex   +1 more source

Recent optical approaches for anatomical and functional dissection of neuron–astrocyte circuitry

The Journal of Physiology, EarlyView.
Abstract figure legend This review summarises novel optical approaches to deciphering structural and functional wiring diagrams of neuron–astrocyte circuits in the brain. There are three groups: the anatomical proximity assay, transsynaptic viral tracing and the functional connection assay. The FRET‐based neuron–astrocyte proximity assay allows mapping
Yoshiki Hatashita, Takafumi Inoue
wiley   +1 more source

The Discovery of Phages in the Substantia Nigra and Its Implication for Parkinson's Disease. [PDF]

Research (Wash D C)
Zhao Y, Xiong C, Wang B, Li D, Liu J, Wei S, Hou Y, Zhou Y, Zheng R.   +8 more
europepmc   +1 more source

Neuroprotective Effects of Intranasal IGF-1 against Neonatal Lipopolysaccharide-Induced Neurobehavioral Deficits and Neuronal Inflammation in the Substantia Nigra and Locus Coeruleus of Juvenile Rats

, 2017
Lu‐Tai Tien, Yih‐Jing Lee, Yi Pang, Silu Lu, Jonathan W. Lee, Chih-Hsueh Tseng, Abhay Bhatt, Renate Savich, Lir‐Wan Fan   +8 more
openalex   +2 more sources

Quantitative Susceptibility Mapping in Skull Base Chordoma: In Silico Analysis and In Vivo Application Towards Indirect Hypoxia Assessment

Magnetic Resonance in Medicine, Volume 95, Issue 4, Page 2092-2105, April 2026.
ABSTRACT Purpose To evaluate quantitative susceptibility mapping (QSM) beyond the brain through realistic simulations and to explore preliminary evidence that may be indicative of hypoxia in skull base chordomas (SBC). Methods Each step of the QSM pipeline was optimized within an in silico framework consisting of (i) phase unwrapping, (ii) background ...
P. Fenech, L. Morelli, G. Parrella, S. Imparato, A. Iannalfi, S. Lillo, E. Orlandi, G. Baroni, C. Paganelli   +8 more
wiley   +1 more source

Disruption of the l‐DOPA Receptor Gpr143/OA1‐Gene in Mice Creates a Unique Mixed Psychosis‐Like Phenotype

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima, Haruko Nakamura, Motokazu Koga, Junka Koyama, Yayoi Kimura, Maya N. Vasishth, Evan Y. Snyder, Masashi Asai, Kenta Sakai, Daiki Masukawa   +9 more
wiley   +1 more source

Effect of age on substantia nigra subregions using neuromelanin-sensitive magnetic resonance imaging overlapping on quantitative susceptibility mapping. [PDF]

Quant Imaging Med Surg
Kuang C, Liu WV, Li L, Liu C, Zha Y.
europepmc   +1 more source

High‐mobility Group Protein 1/ Receptor for Advanced Glycation End Products/ Nuclear Factor‐κB Signalling Pathway Contributes to the Pathogenic Process of Striatal Neuron Impairment in the Rat Model of Parkinson's Disease

Brain and Behavior, Volume 16, Issue 2, February 2026.
In Parkinson's disease, the death of dopamine neurons in the substantia nigra, resulting in a decrease in dopamine levels in the striatum. This leads to striatal damage through the HMGB1/RAGE/NF‐κB signaling pathway, thereby inducing motor and cognitive dysfunction.
Yaofeng Zhu, Zean Du, Liping Sun, Ziyun Huang, Linju Jia, Tao Chen, Xuefeng Zheng, Wanlong Lei   +7 more
wiley   +1 more source