Recent optical approaches for anatomical and functional dissection of neuron–astrocyte circuitry
The Journal of Physiology, EarlyView.Abstract figure legend This review summarises novel optical approaches to deciphering structural and functional wiring diagrams of neuron–astrocyte circuits in the brain. There are three groups: the anatomical proximity assay, transsynaptic viral tracing and the functional connection assay. The FRET‐based neuron–astrocyte proximity assay allows mapping
Yoshiki Hatashita, Takafumi Inoue
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Localization of Melanocortin 1 Receptor in the Substantia Nigra. [PDF]
Int J Mol SciEhara A, Ito N, Nakadate K, Tokuda N.
europepmc +1 more source
Modulation of cardiac activity by tachykinins in the rat substantia nigra [PDF]
, 2001 Andrée Lessard, Réjean Couture
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Atypical Frontotemporal Dementia Associated With SQSTM1 Gene Mutation: A Clinicopathological Case
Neuropathology, Volume 45, Issue 6, December 2025.ABSTRACT A 78‐year‐old man presented with a six‐year history of progressive memory decline, initially manifesting as recent memory impairment and mild anomia, which gradually evolved into motor clumsiness, gait disturbances, language difficulties, behavioral changes, and late‐onset parkinsonism. He had been diagnosed with Paget disease of bone (PDB) at
Christian Espinoza‐Vinces +8 more
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The effect of cannabinoid type Ⅱ receptor on the excitability of substantia nigra dopaminergic neurons. [PDF]
Front PharmacolZhao S, Liu S, Gong Y, Ma Z.
europepmc +1 more source
Differential Subcellular Localization of mGluR1a and mGluR5 in the Rat and Monkey Substantia Nigra [PDF]
, 2001 George W. Hubert +2 more
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Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline
Annals of Neurology, Volume 98, Issue 5, Page 1014-1026, November 2025.Objective To investigate how sex and age at menopause influence the interplay between Alzheimer's disease (AD) and Lewy body disease (LBD) neuropathologies, and their associations with cognitive decline. Methods We analyzed data from: (1) three Rush Alzheimer's Disease Center cohorts (i.e., the Religious Orders Study, Rush Memory and Aging Project, and
Madeline Wood Alexander +17 more
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High-resolution mapping of substantia nigra in Parkinson's disease using 7 tesla magnetic resonance imaging. [PDF]
NPJ Parkinsons DisMadelung CF +8 more
europepmc +1 more source
Dendritic Arborizations of the Rat Substantia Nigra Pars Reticulata Neurons: Spatial Organization and Relation to the Lamellar Compartmentation of Striato-Nigral Projections [PDF]
, 2001 Philippe Mailly +6 more
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Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy
Annals of Neurology, Volume 98, Issue 5, Page 991-1003, November 2025.Objective Exenatide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has neuroprotective effects in preclinical models of multiple system atrophy (MSA). We investigated these effects in a proof‐of‐concept clinical trial. Methods In this single‐center, randomized, open label trial, participants with MSA were randomly assigned (1:1) to receive ...
Nirosen Vijiaratnam +29 more
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