Results 231 to 240 of about 76,030 (307)

Substantia nigra (illustration)

, 2014
openaire   +1 more source

The effect of cannabinoid type Ⅱ receptor on the excitability of substantia nigra dopaminergic neurons. [PDF]

Front Pharmacol
Zhao S, Liu S, Gong Y, Ma Z.
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Expression of Genes Encoding Receptors for Classical Neurotransmitters, Neuropeptides and Hormones in the Substantia Nigra, Especially in Dopaminergic Neurons, in Intact Mice and Mouse Models of Parkinson's Disease. [PDF]

Cells
Troshev D, Pavlova E, Bogdanov V, Ugrumov M.   +3 more
europepmc   +1 more source

Factor Analysis of the Neurological Evaluation Scale (NES) and Corresponding Brain Function and Structures

International Journal of Methods in Psychiatric Research, Volume 35, Issue 1, March 2026.
ABSTRACT Objective Neurological soft signs (NSS) are minor, non‐localizable neurological abnormalities. This study aimed to investigate the factor structure of the Neurological Evaluation Scale. Material and Methods A total of 355 subjects (233 patients and 122 general population subjects). NSS were assessed using the NES.
Konstantinos N. Fountoulakis, Calypso Mitkani, Theocharis Kyziridis, Panagiotis Panagiotidis, Eva‐Maria Tsapakis   +4 more
wiley   +1 more source

Autologous Peripheral Nerve Tissue Grafts Implanted into the Nucleus Basalis of Meynert and Substantia Nigra at the Time of Bilateral Deep Brain Stimulation in Parkinson Disease: A Report of 2 Cases. [PDF]

Neurosurg Pract
Daly SR, Quintero JE, Koehl L, Wallace E, Guduru Z, Gurwell JA, Hines T, Hixson J, Hulou S, Slevin JT, Schmitt FA, Gerhardt GA, van Horne CG.   +12 more
europepmc   +1 more source

Disruption of the l‐DOPA Receptor Gpr143/OA1‐Gene in Mice Creates a Unique Mixed Psychosis‐Like Phenotype

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima, Haruko Nakamura, Motokazu Koga, Junka Koyama, Yayoi Kimura, Maya N. Vasishth, Evan Y. Snyder, Masashi Asai, Kenta Sakai, Daiki Masukawa   +9 more
wiley   +1 more source

High-resolution mapping of substantia nigra in Parkinson's disease using 7 tesla magnetic resonance imaging. [PDF]

NPJ Parkinsons Dis
Madelung CF, Løkkegaard A, Fuglsang SA, Marques MM, Boer VO, Madsen KH, Hejl AM, Meder D, Siebner HR.   +8 more
europepmc   +1 more source

A unified 3D reconstruction of microscopy and MRI in a brain showing Alzheimer's disease‐related neuropathology

Brain Pathology, Volume 36, Issue 2, March 2026.
Post mortem MRI was combined with neuropathological assessments at 600 μm intervals throughout the brain. Through this approach, a three dimensional account of an entire human brain with an intermediate Alzheimer's disease neuropathologic change was created.
Anneke Alkemade, Pierre‐Louis Bazin, Evgeniya Kirilina, Kerrin Pine, Andreas Herrler, Ronald L. A. W. Bleijs, J. Max Kros, Lysanne Groenewegen, Sanne M. M. Vermorgen, Laura E. Jonkman, Dick F. Swaab, Rawien Balesar, Nikolaus Weiskopf, Birte U. Forstmann   +13 more
wiley   +1 more source

Contribution of glutamatergic projections to neurons in the nonhuman primate substantia nigra pars reticulata for reactive inhibition. [PDF]

Proc Natl Acad Sci U S A
Yoshida A, Hikosaka O.
europepmc   +1 more source