Results 81 to 90 of about 1,979,897 (278)

Relationships between substrate and the mobilization of reserve with temperature during seed germination of Ormosia coarctata Jack.

open access: yesJournal of Seed Science, 2020
: Seed germination studies provide essential information for biodiversity conservation and ecological restoration programs. This work aimed to investigate the relationship between the substrates and the mobilization of reserves during germination of ...
Luciane Pereira Reis   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Diet of Phylloicus (Trichoptera: Calamoceratidae) caddisfly larvae in forest streams of western Pará, central Brazilian Amazonia

open access: yesActa Limnologica Brasiliensia, 2020
: Aim The aquatic larvae of the Phylloicus (Trichoptera: Calamoceratidae) caddisflies are typical shredders. However, the trophic classification of Phylloicus has been based on the morphology and behaviour of the larvae.
Diego Ramos Pimentel   +2 more
doaj   +1 more source

Directed enzyme evolution: climbing fitness peaks one amino acid at a time [PDF]

open access: yes, 2009
Directed evolution can generate a remarkable range of new enzyme properties. Alternate substrate specificities and reaction selectivities are readily accessible in enzymes from families that are naturally functionally diverse.
Arnold, Frances H., Tracewell, Cara A.
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Computing Substrates and Life

open access: yes, 2006
Alive matter distinguishes itself from inanimate matter by actively maintaining a high degree of inhomogenous organisation. Information processing is quintessential to this capability.
Gunji, Yukio-Pegio   +2 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Comportamiento de Malassezia furfur en medios de cultivo con base en los exudados gomosos de Spondias dulcis y Spondias mombin. Producción de lipasa extracelular

open access: yesKasmera, 2011
: The development of genus Malassezia yeasts requires special conditions. This fungus, which produces skin diseases, is generally cultivated in the Dixon medium.
Mesa C Luz Mila   +5 more
doaj  

Substrates for Expansion of Corneal Endothelial Cells towards Bioengineering of Human Corneal Endothelium

open access: yesJournal of Functional Biomaterials, 2015
Corneal endothelium is a single layer of specialized cells that lines the posterior surface of cornea and maintains corneal hydration and corneal transparency essential for vision.
Jesintha Navaratnam   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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