Results 11 to 20 of about 2,773 (218)
Chronotropic action of immobilized subtilisins during the perfusion of an isolated rat heart
Сибирский научный медицинский журнал, 2022 The pharmacological experiments on isolated organs (ex vivo) are the preferred method for assessing the primary pharmacodynamics of the studied drugs, since this method is completely excluded the systemic influence of neurohumoral regulation. In the last
G. I. Baikalov +5 more
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Proceedings of the National Academy of Sciences, 1973 Subtilisin reacts at pH 6.8-7.8 with p -nitrophenyl diazoacetate to release p -nitrophenol and form diazoacetyl subtilisin. Although at pH 7.8 this derivative rapidly undergoes hydrolytic cleavage to regenerate active enzyme, the derivative can be trapped by rapidly lowering the pH to 5 ...
Y, Stefanovsky, F H, Westheimer
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Horizontal transfer of a subtilisin gene from plants into an ancestor of the plant pathogenic fungal genus Colletotrichum. [PDF]
PLoS ONE, 2013 The genus Colletotrichum contains a large number of phytopathogenic fungi that produce enormous economic losses around the world. The effect of horizontal gene transfer (HGT) has not been studied yet in these organisms.
Vinicio Danilo Armijos Jaramillo +3 more
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Hepatology, EarlyView., 2022 Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince +30 more
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New insights into the evolution and structure of Colletotrichum plant-like subtilisins (CPLSs) [PDF]
, 2013 The Colletotrichum plant-like subtilisins (CPLSs) are a family of proteins found only in species of the phytopathogenic fungus Colletotrichum. CPLSs have high similarity to plant subtilisins and our previous work has shown that they were acquired by an ...
Armijos Jaramillo, Vinicio +3 more
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Frontiers in Cellular and Infection Microbiology, 2022 Proteases are virulence factors with a recognized impact on the Leishmania spp. life cycle. This study considers a set of analyses measuring phenotypic factors of L.
Anabel Zabala-Peñafiel +10 more
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Interaction of subtilisins with serpins [PDF]
Protein Science, 1996 AbstractSerpins are well‐characterized inhibitors of the chymotrypsin family serine proteinases. We have investigated the interaction of two serpins with members of the subtilisin family, proteinases that possess a similar catalytic mechanism to the chymotrypsins, but a totally different scaffold.
T, Komiyama +3 more
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Scientific Reports, 2021 Glucantime (SbV) is the first-line treatment against American Tegumentary Leishmaniasis. Resistance cases to this drug have been reported and related to host characteristics and parasite phenotypes.
Anabel Zabala-Peñafiel +10 more
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Treatment of wool fibres with subtilisin and subtilisin-PEG [PDF]
Enzyme and Microbial Technology, 2005 Abstract In this work the diffusion of serine proteases into wool fabrics and yarns was studied. The proteases used were free subtilisin and subtilisin-PEG (the same enzyme that was covalently cross linked to polyethylene glycol). It is shown that the adsorption and diffusion is facilitated by the pre-treatment performed, being the alkaline ...
Silva, Carla J. S. M. +3 more
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Directed evolution converts subtilisin E into a functional equivalent of thermitase [PDF]
, 1999 We used directed evolution to convert Bacillus subtilis subtilisin E into an enzyme functionally equivalent to its thermophilic homolog thermitase from Thermoactinomyces vulgaris.
Arnold, Frances H., Zhao, Huimin
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