A single dose investigational subunit vaccine for human use against Nipah virus and Hendra virus
npj Vaccines, 2021 Nipah and Hendra viruses are highly pathogenic bat-borne paramyxoviruses recently included in the WHO Blueprint priority diseases list. A fully registered horse anti-Hendra virus subunit vaccine has been in use in Australia since 2012.
Thomas W. Geisbert +11 more
doaj +2 more sources
Advances in Oral Subunit Vaccine Design [PDF]
Vaccines, 2020 Many pathogens invade the host at the intestinal surface. To protect against these enteropathogens, the induction of intestinal secretory IgA (SIgA) responses is paramount.
Hans Van der Weken, E. Cox, B. Devriendt
semanticscholar +5 more sources
Efficacy Evaluation of an E2 Subunit Vaccine Against Highly Virulent Classical Swine Fever Virus Strain [PDF]
VaccinesBackground/Objectives: Classical swine fever (CSF) is listed by the World Organisation for Animal Health as a highly devastating and contagious pig disease, causing severe economic losses to the swine industry.
Yu-Chieh Chen +5 more
doaj +2 more sources
Scientific Reports, 2018 Malaria fever has been pervasive for quite a while in tropical developing regions causing high morbidity and mortality. The causal organism is a protozoan parasite of genus Plasmodium which spreads to the human host by the bite of hitherto infected ...
Rajan Kumar Pandey +2 more
doaj +2 more sources
Immunoinformatic design of a COVID-19 subunit vaccine using entire structural immunogenic epitopes of SARS-CoV-2 [PDF]
Scientific Reports, 2020 Coronavirus disease 2019 (COVID-19) is an acute pneumonic disease, with no prophylactic or specific therapeutical solution. Effective and rapid countermeasure against the spread of the disease’s associated virus, SARS-CoV-2, requires to incorporate the ...
Esmaeil Behmard +3 more
openalex +2 more sources
Fusion membrane proteins derived subunit vaccine candidates effectively protect against Mycoplasma bovis challenge in mice [PDF]
BMC Veterinary ResearchMycoplasma bovis (M. bovis) is the causative agent of bovine mycoplasmosis, a disease that can lead to respiratory issues, otitis media, mastitis, and arthritis in cattle and causes huge economic losses to the cattle breeding industry.
Yong Xuan Wang +8 more
doaj +2 more sources
Vaccine profile of herpes zoster (HZ/su) subunit vaccine
Expert Review of Vaccines, 2017 Introduction: Herpes zoster (HZ) causes an often severe and painful rash in older people and may be complicated by prolonged pain (postherpetic neuralgia; PHN) and by dissemination in immune-compromised patients.
Anthony L. Cunningham, Thomas Heineman
doaj +3 more sources
Multi-Stage Tuberculosis Subunit Vaccine Candidate LT69 Provides High Protection against Mycobacterium tuberculosis Infection in Mice. [PDF]
PLoS ONE, 2015 Effective tuberculosis (TB) vaccine should target tubercle bacilli with various metabolic states and confer long-term protective immunity. In this study, we constructed a novel multi-stage TB subunit vaccine based on fusion protein ESAT6-Ag85B-MPT64(190 ...
Hongxia Niu +11 more
doaj +5 more sources
A QS21+ CpG-Adjuvanted Rabies Virus G Subunit Vaccine Elicits Superior Humoral and Moderate Cellular Immunity [PDF]
VaccinesBackground: Rabies remains a fatal zoonotic disease caused by rabies virus (RABV), posing substantial global health challenges. Current vaccine production faces challenges in manufacturing efficiency and cost-effectiveness. The RABV glycoprotein (RABV-G)
Han Cao +7 more
doaj +2 more sources
The subunit vaccine of Lumpy skin disease virus elicits significant humoral and cell-mediated immune responses in mice [PDF]
Front Vet SciXiaoxiao Gu +7 more
openalex +2 more sources