Immunogenicity of subunit vaccine of E2 protein against atypical porcine pestivirus in pigs. [PDF]
Huang Y +5 more
europepmc +1 more source
Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man +7 more
wiley +1 more source
VSA-2-, a novel plant-derived adjuvant for SARS-CoV-2 subunit vaccine. [PDF]
Adam A +8 more
europepmc +1 more source
ABSTRACT Background and Aims The immediate and long‐term effects of COVID‐19 pandemic on the children go beyond just being a viral infection. A child's mental health and psychological issues like irritability, anxiety, sadness, non‐attentiveness, attention deficit and hyperactive disorder needed evaluation.
Ranjan K. Mohapatra +20 more
wiley +1 more source
AntiPan: a genome-informed in silico pipeline for advancing subunit vaccine discovery against Staphylococcus aureus. [PDF]
Ibrahim MS +8 more
europepmc +1 more source
Cellular Immune Response Induced by mRNA Vaccines Against SARS‐CoV‐2
SARS‐CoV‐2 vaccine induces cellular immune response. T‐cells play a protective role for COVID‐19. ABSTRACT The disease caused by SARS‐CoV‐2 is known as COVID‐19, and it can range from mild symptoms to severe clinical manifestations, including respiratory failure, pneumonia, and organ failure. Since its emergence in 2019, more than 7 million deaths have
Valentina Tovar +4 more
wiley +1 more source
Honey Bee AMPs as a Novel Carrier Protein for the Development of a Subunit Vaccine: An Immunoinformatic Approach. [PDF]
Dinata R +3 more
europepmc +1 more source
New Perspective: Bench to Bedside Evidence of the Role of CD8+ T Cells in Alzheimer's Disease
Emerging evidence highlights a previously underappreciated role of CD8+ T cells in Alzheimer's disease (AD). Beyond amyloid‐β and tau pathology, CD8+ T‐cell subsets infiltrate the central nervous system and exhibit functional heterogeneity. Cytotoxic effector CD8+ T cells may exacerbate neuroinflammation and neuronal injury, whereas regulatory or ...
Yong Peng +10 more
wiley +1 more source
Engineered Low-Endotoxin Bacterial Biomimetic Vesicles for Enhanced Oral Dual-Antigen Subunit Vaccine Delivery. [PDF]
Shen X +11 more
europepmc +1 more source
This study integrates two decades of surveillance with genomic and structural analyses to decipher how spike protein glycosylation haplotypes drive avian coronavirus evolution. We uncover how specific glycosylation patterns associate with receptor‐binding affinity, shape global transmission dynamics, and correlate with clinical outcomes.
Hao Zhang +21 more
wiley +1 more source

