Results 11 to 20 of about 81,530 (252)
Vaccine profile of herpes zoster (HZ/su) subunit vaccine
Expert Review of Vaccines, 2017 Introduction: Herpes zoster (HZ) causes an often severe and painful rash in older people and may be complicated by prolonged pain (postherpetic neuralgia; PHN) and by dissemination in immune-compromised patients.
Anthony L. Cunningham, Thomas Heineman
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Subunit vaccines for Acinetobacter baumannii
Frontiers in Immunology, 2023 Acinetobacter baumannii is a gram-negative bacterium and a crucial opportunistic pathogen in hospitals. A. baumannii infection has become a challenging problem in clinical practice due to the increasing number of multidrug-resistant strains and their prevalence worldwide. Vaccines are effective tools to prevent and control A. baumannii infection.
Ning Yang +6 more
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Advances in Oral Subunit Vaccine Design [PDF]
Vaccines, 2020 Many pathogens invade the host at the intestinal surface. To protect against these enteropathogens, the induction of intestinal secretory IgA (SIgA) responses is paramount. While systemic vaccination provides strong systemic immune responses, oral vaccination is the most efficient way to trigger protective SIgA responses.
Hans Van der Weken +2 more
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Journal of General Virology, 1983 Conclusions The secondary and tertiary structures of the rabies virus spike G protein are important for its ability to induce VN antibodies and confer immunity to the host. For a subunit peptide vaccine to be as effective as the native spike G protein, it would appear that the amino acid sequence comprising the antigenic determinant for VN antibody ...
W H, Wunner +3 more
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PLoS ONE, 2012 Recent studies have demonstrated the effectiveness of vaccine delivery to the skin by vaccine-coated microneedles; however there is little information on the effects of adjuvants using this approach for vaccination.
William C Weldon +8 more
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Raising Expectations For Subunit Vaccine [PDF]
The Journal of Infectious Diseases, 2014 Multidose regimens are recommended for all prophylactic subunit vaccines. Recent findings from clinical trials of an human papillomavirus virus-like particle vaccine suggest that it may be possible to develop effective single-dose subunit vaccines.
John T, Schiller, Douglas R, Lowy
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npj Vaccines, 2022 Protein or peptide-based subunit vaccines have generated excitement and renewed interest in combating human cancer or COVID-19 outbreak. One major concern for subunit vaccine application is the weak immune responses induced by protein or peptides ...
Ning Yang +6 more
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PLoS ONE, 2023 Subunit vaccines feature critical advantages over other vaccine platforms such as stability, price, and minimal adverse effects. To maximize immunological protection of subunit vaccines, adjuvants are considered as main components that are formulated ...
Sedthawut Laotee +15 more
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Future Path Toward TB Vaccine Development: Boosting BCG or Re-educating by a New Subunit Vaccine
Frontiers in Immunology, 2018 Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb), kills 5,000 people per day globally. Rapid development and spread of various multi drug-resistant strains of Mtb emphasize that an effective vaccine is still the most ...
Nancy Gupta +5 more
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Viral Subunits for Rabies Vaccination [PDF]
Nature, 1969 RECENT work with adenovirus1, Sindbis virus2 and the viruses causing influenza3, measles4, vesicular stomatitis5 and German measles6 has shown that subunits of the viruses can stimulate the production of neutralizing antibodies, and in some cases can be used as vaccines.
J, Crick, F, Brown
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