Results 111 to 120 of about 3,444 (280)

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

Mobocertinib Succinate

open access: yesAmerican Journal of Health-System Pharmacy, 2021
openaire   +2 more sources

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer   +11 more
wiley   +1 more source

Second‐trimester multimetabolite panel for early preeclampsia rule‐out

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective We aimed to establish a high‐sensitivity, multimetabolite rule‐out model for the development of preeclampsia (PE), prioritizing minimizing false negatives to exclude low‐risk individuals from intensive surveillance confidently. Methods In this prospective, nested case–control study, maternal serum samples were collected between 20+0 ...
Matthews Silva Martins   +7 more
wiley   +1 more source

Effect of Ca2+ doping and annealing temperature on the structure, morphology and magnetic behavior of CaxCo1-xFe2O4/SiO2 nanocomposites

open access: yesResults in Physics
Co-doped ferrites are promising functional materials for many practical applications and their physical properties can be tailored by changing their composition. This study assesses the structure, morphology and magnetic properties of CaxCo1-xFe2O4/SiO2 (
Thomas Dippong   +4 more
doaj   +1 more source

Studies on the Thermodynamics of Ion Association in Aqueous Solutions [PDF]

open access: yes, 1961
The association in aqueous solutions between divalent transition metal cations and the anions of dicarboxylic acids has been studied. The thesis is divided into four parts.
McAuley, Alexander
core  

Succinate [PDF]

open access: yesNeurosurgery, 2015
Alp Ozpinar   +2 more
openaire   +1 more source

Two stable gut microbiome guilds predict liver tumor class and treatment responses

open access: yesiMeta, EarlyView.
Gut microbiome alterations are linked to hepatocellular carcinoma (HCC), yet taxon‐based biomarkers often lack reproducibility. Using shotgun metagenomics from 120 resectable HCC (MT) and 76 benign hepatic tumor controls (BT), we reconstructed a stable interaction‐based Two Competing Guilds model (HCC‐TCG) comprising 142 genomes organized into two ...
Yang Liu   +17 more
wiley   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

open access: yesiNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao   +3 more
wiley   +1 more source

Monocytes with trained immunity–like signatures are associated with acute anterior uveitis in ankylosing spondylitis

open access: yesInterdisciplinary Medicine, EarlyView.
In ankylosing spondylitis‐acute anterior uveitis (AS‐AAU), trained immunity monocytes (Mono‐TI) differentiate into macrophages in the eye, retaining trained immunity features. Mono‐TI cells secrete pro‐inflammatory cytokines and chemokines, including IL‐1β, TNF‐α, and CCL3.
Yimeng Sun   +13 more
wiley   +1 more source

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