Results 71 to 80 of about 3,444 (280)

Single‐Mitochondrion ATP Profiling Directs Discovery of Targetable OXPHOS Dependency in Cancers

Advanced Science, EarlyView.
MitoATP‐nFCM integrates nano‐flow cytometry with fluorogenic probes (ATP/membrane potential) and antibodies to quantify mitochondrial metabolites and protein expression at single‐organelle resolution, exposing oxidative phosphorylation (OXPHOS)‐driven metabolic rewiring in cancers.
Xu Xiao, Cheng Lu, Hao Chen, Jing Zhou, Yunyun Hu, Haonan Di, Guoqiang Su, Xiaomei Yan   +7 more
wiley   +1 more source

The Audio Frequency Conductance Study of Some Metal Succinate Salts in Aqueous Medium at Different Temperatures (Part I: Magnesium, Manganese (II), Barium and Copper Succinates)

Journal of Chemistry, 2013
The audio electrical conductances of aqueous solutions of magnesium, manganese II, barium, and copper succinates have been measured at various temperatures in the range of 298.15 K to 313.15 K, using an audio frequency conductance bridge.
Kosrat N. Kaka, Anis A. Al-Najar, Wali M. Hamad   +2 more
doaj   +1 more source

Enzymes involved in the anaerobic oxidation of n-alkanes: from methane to long-chain paraffins

Frontiers in Microbiology, 2013
Anaerobic microorganisms play key roles in the biogeochemical cycling of methane and non-methane alkanes. To date, there appear to be at least three proposed mechanisms of anaerobic methane oxidation (AOM). The first pathway is mediated by consortia of
Amy V. Callaghan
doaj   +1 more source

ETV4 Promotes Colorectal Cancer Progression by Reprogramming Asparagine Metabolism to Remodel the Stromal Microenvironment

Advanced Science, EarlyView.
ETV4 coordinates a dual transcriptional program by upregulating MET and asparagine synthetase (ASNS). The resulting asparagine (Asn) secretion acts as a metabolic signal, reprogramming hepatic stellate cells (HSCs) and primary cancer‐associated fibroblasts (CAFs) toward an inflammatory phenotype. These activated stromal cells release HGF to sustain the
Dujiang Fu, Meijia Zhang, Maoping Cai, Miao Wang, Ziao Huang, Zesheng Lin, Yixin Liu, Wang Qian, Guopeng Chen, Yuxing Liang, Dongyi Wei, Jing xie, Picheng Yan, Yuanyuan Qu, Yongchang Wei   +14 more
wiley   +1 more source

Synthesis and characterization of novel poly(butylene succinate-co-2-methyl-1,3-propylene succinate)s

eXPRESS Polymer Letters, 2011
Poly(butylene succinate) (PBSu), poly(2-methyl-1,3-propylene succinate) (PMPSu), and PBSu-rich copolyesters were synthesized using an effective catalyst, titanium tetraisopropoxide.
doaj   +1 more source

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, EarlyView.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Application of luciferase assay for ATP to antimicrobial drug susceptibility [PDF]

, 1977
The susceptibility of bacteria, particularly those derived from body fluids, to antimicrobial agents is determined in terms of an ATP index measured by culturing a bacterium in a growth medium.
Barza, M. J., Chappelle, E. W., Picciolo, G. L., Tuttle, S. A., Vellend, H., Weinstein, L.   +5 more
core   +1 more source

Role of carboxylate ion and metal oxidation state on the morphology and magnetic properties of nanostructured metal carboxylates and their decomposition products [PDF]

, 2008
Sub-micron rods and spheres of cobalt succinate sesquihydrate and iron succinate trihydrate/pentahydrate respectively have been synthesized by the reverse micellar route. These precursors are an excellent source for the synthesis of metal and metal oxide
Ahmad, Tokeer, Das, Dipankar, Ganguli, Ashok K., Ganguly, Aparna, Kundu, Rituparna, Lofland, Samuel E., Ramanujachary, Kandalam V., Vasanthacharya, N. Y.   +7 more
core   +1 more source

Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes

Advanced Science, EarlyView.
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang, Ning Lu, Xin‐Xiu Lin, Xu‐Hui Fang, Yi‐Hui Li, Qing‐Peng Luo, Yu‐Ting Peng, Gil Mor, Ai‐Hua Liao   +8 more
wiley   +1 more source

Versatile transformations of hydrocarbons in anaerobic bacteria: substrate ranges and regio- and stereochemistry of activation reactions

Frontiers in Microbiology, 2015
Anaerobic metabolism of hydrocarbons proceeds either via addition to fumarate or by hydroxylation in various microorganisms, e.g. sulfate-reducing or denitrifying bacteria, which are specialized in utilizing n-alkanes or alkylbenzenes as growth ...
René eJarling, Simon eKühner, Eline eBasílio Janke, Andrea eGruner, Marta eDrozdowska, Bernard T. Golding, Ralf eRabus, Ralf eRabus, Heinz eWilkes, Heinz eWilkes   +9 more
doaj   +1 more source