Results 91 to 100 of about 7,622 (205)
MedComm – Oncology, Volume 5, Issue 1, March 2026.Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
Scientific Reports, 2017 Lysine succinylation is a novel dynamic and evolutionarily conserved post-translational modification (PTM) that regulates various biological processes. ‘Anji Baicha’ is an albino tea variety that exhibits temperature-based variability of leaf colour and ...
Yan-Xia Xu +6 more
doaj +1 more source
The Role of One‐Carbon Metabolism in Cancer and Its Therapeutic Significance
MedComm – Oncology, Volume 5, Issue 1, March 2026.One‐Carbon metabolism in T‐cell activation and tumor competition. T‐cell activation shifts metabolic pathways, promoting anabolic metabolism and bioenergetic capacity. One‐carbon metabolism plays a crucial role in histone and DNA methylation in activated T cells.
Yuting Jiang +3 more
wiley +1 more source
Targeted and non-targeted liquid chromatography-mass spectrometric workflows for identification of transformation products of emerging pollutants in the aquatic environment [PDF]
, 2015 Identification of transformation products (TPs) of emerging pollutants is challenging, due to the vast number of compounds, mostly unknown, the complexity of the matrices and their often low concentrations, requiring highly selective, highly sensitive ...
Archontaki, Eleni +4 more
core +1 more source
Protocol for identifying OXCT1-mediated LACTB succinylation sites in vitro
STAR ProtocolsSummary: OXCT1 acts as a succinyltransferase to promote serine beta-lactamase-like protein (LACTB) K284 succinylation. Here, we present a protocol for detecting OXCT1-mediated LACTB succinylation levels and sites.
Wenhao Ma, Yuchen Sun, Huafeng Zhang
doaj +1 more source
Overexpression of mitochondrial sirtuins alters glycolysis and mitochondrial function in HEK293 cells [PDF]
, 2014 SIRT3, SIRT4, and SIRT5 are mitochondrial deacylases that impact multiple facets of energy metabolism and mitochondrial function. SIRT3 activates several mitochondrial enzymes, SIRT4 represses its targets, and SIRT5 has been shown to both activate and ...
De Moura, MB +4 more
core +2 more sources
International Journal of Nanomedicine, 2017 Md Mehedi Hasan,1 Mst Shamima Khatun,2 Md Nurul Haque Mollah,2 Cao Yong,3 Dianjing Guo1 1School of Life Sciences and the State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Shatin, New Territory, Hong Kong, People’s ...
Hasan MM +4 more
doaj
A novel mass spectrometric strategy "bEMAP" reveals Extensive O-linked protein glycosylation in Enterotoxigenic Escherichia coli [PDF]
, 2016 © The Author(s) 2016. The attachment of sugars to proteins via side-chain oxygen atoms (O-linked glycosylation) is seen in all three domains of life.
Boysen, A +5 more
core +2 more sources
BMC Veterinary ResearchBackground Peste des petits ruminants virus (PPRV) is currently the only member of the Morbillivirus caprinae species within the genus Morbillivirus of the family Paramyoxviridae.
Xuelian Meng +5 more
doaj +1 more source