Results 81 to 90 of about 6,092 (196)

Succinyl-coenzyme A: a key metabolite and succinyl group donor in erythropoiesis

Haematologica
Not available.
openaire   +3 more sources

Histone acetyltransferase 1 promotes postinfarction inflammatory response by regulation of monocyte histone succinylation

Nature Communications
Early activation and phenotypic transformation of monocytes and macrophages are essential for inflammatory activities and tissue repair following myocardial infarction (MI).
Yutong Guo, Jie Xiong, Zhaoyue Li, Liyan Bai, Bo Wang, Bingchen Guo, Hao Tang, Guanghui Li, Yi Qiu, Lin Lv, Zengxiang Dong, Yingfeng Tu   +11 more
doaj   +1 more source

Protocol for identifying OXCT1-mediated LACTB succinylation sites in vitro

STAR Protocols
Summary: OXCT1 acts as a succinyltransferase to promote serine beta-lactamase-like protein (LACTB) K284 succinylation. Here, we present a protocol for detecting OXCT1-mediated LACTB succinylation levels and sites.
Wenhao Ma, Yuchen Sun, Huafeng Zhang
doaj   +1 more source

Ultrasonic-boosted succinylation of walnut protein isolate: Unlocking enhanced functionalities and structural insights

Food Chemistry: X
This study aims to improve the functional properties of walnut protein isolate (WPI), particularly its solubility and interfacial activity, through ultrasound-assisted succinylation. WPI was treated with succinic anhydride at concentrations of 5 %, 10 %,
Weizhuo Zhu, Liping Sun, Ying Gu, Yongliang Zhuang, Gaopeng Zhang, Xuejing Fan, Yangyue Ding   +6 more
doaj   +1 more source

Succinylation regulates boar sperm linear motility via reprogramming glucose metabolism

Succinylation is a recently identified post-translational modification (PTM) that modulates enzyme activity and metabolism. However, how it regulates metabolic reprogramming in sperm remains unclear.
Wenxian Zeng, Shanpeng Wang, Adedeji O. Adetunji, Lingjiang Min, Zhendong Zhu, Masayuki Shimada, Qi Wang   +6 more
core   +1 more source

Succinylation Is a Gain-of-Function Modification in Human Lens αB-Crystallin

, 2019
Acylation of lysine residues is a common post-translational modification of cellular proteins. Here, we show that lysine succinylation, a type of acylation, occurs in human lens proteins.
Cole Michel (6383282), Rooban B. Nahomi (6383279), Ram H. Nagaraj (335269), Alexandra Dunbar, Sandip K. Nandi (6383276), Cole Michel, Stefan Rakete, Rooban B. Nahomi, Kristofer S. Fritz, Alexandra Dunbar (6383285), Stefan Rakete (1739833), Kristofer S. Fritz (159782), Sandip K. Nandi, Ram H. Nagaraj   +13 more
core   +1 more source

Supramolecular assembly of KAT2A with succinyl-CoA for histone succinylation [PDF]

Cell Discovery, 2018
Wang, Yugang, Guo, Yusong R., Xing, Dongming, Tao, Yizhi Jane, Lu, Zhimin   +4 more
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Succinylome Analysis Reveals the Involvement of Lysine Succinylation in Metabolism in Pathogenic Mycobacterium tuberculosis

, 2015
Mycobacterium tuberculosis (Mtb), the causative agent of human tuberculosis, remains one of the most prevalent human pathogens and a major cause of mortality worldwide.
Chen, Chuangbin, Cheng, Zhongyi, Bi, Lijun, Chen, Ying, Yang, Mingkun, Ge, Feng, Mo, Ran, Gu, Jing, Wang, Xude, Wang, Yan, Deng, Jiaoyu, Ge, F (reprint author), Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China.   +11 more
core   +1 more source

Chromatin Succinylation Correlates with Active Gene Expression and Is Perturbed by Defective TCA Cycle Metabolism

iScience, 2018
Summary: Succinylation is a post-translational protein acylation modification that converts the cationic lysine side chain to an anion with large potential impacts on protein structure and function. Here we characterize the epigenome-wide distribution of
John Smestad, Luke Erber, Yue Chen, L. James Maher, III   +3 more
doaj   +1 more source

Escherichia coli succinyl coenzyme A synthetase. Inhibition of ATP-stimulated succinate—-succinyl coenzyme A exchange at low succinyl coenzyme A concentrations by an ADP trap.

Journal of Biological Chemistry, 1984
The hypothesis that Escherichia coli succinyl-CoA synthetase functions by a cooperative alternating sites mechanism is based largely on the results of [18O]phosphate exchange experiments (Bild, G. S., Janson, C. A., and Boyer, P. D. (1980) J. Biol. Chem. 255, 8109-8115).
J S, Nishimura, T, Mitchell
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